Warning
This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.

Tryptamine (compound)

From PsychonautWiki Archive
Jump to navigation Jump to search
Tryptamine (compound)
{{{SkeletalImageWidth}}}
{{{SkeletalImageWidth}}}
Chemical Nomenclature
Common names Indolylethylamine
Systematic name 2-(1H-indol-3-yl)ethanamine
Class Membership
Chemical class Arylethylamine / Indole
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.












DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions


For the chemical class based on the tryptamine structure, see Substituted tryptamine.

Tryptamine is a monoamine alkaloid found in animals, plants and fungi.[citation needed] It contains an indole ring structure, and is structurally similar to the amino acid tryptophan, from which the name derives. Tryptamine is found in trace amounts in the brains of mammals and is hypothesized to play a role as a neuromodulator or neurotransmitter.[1]

Chemistry

The tryptamine molecule is an indole alkaloid comprised of an indole ring attached to a monoamine (single nitrogen group-containing) chain. It is a derivative of the amino acid tryptophan.

Pharmacology

Tryptamine is hypothesized to play a role as a neuromodulator or neurotransmitter.[1] Similar to other trace amines, tryptamine binds to human trace amine-associated receptor 1 (TAAR1) as an agonist.[2]

See also

References

  1. ↑ 1.0 1.1 Jones, R. S. G. (January 1982). "Tryptamine: a neuromodulator or neurotransmitter in mammalian brain?". Progress in Neurobiology. 19 (1–2): 117–139. doi:10.1016/0301-0082(82)90023-5. ISSN 0301-0082. 
  2. ↑ Khan, M. Z., Nawaz, W. (October 2016). "The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system". Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 83: 439–449. doi:10.1016/j.biopha.2016.07.002. ISSN 1950-6007. 
Retrieved from "https://psy.st/index.php?title=Tryptamine_(compound)&oldid=490241"