This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
For common legal drug precursors that can be converted to psychoactive substances, see: Conversion of CBD to THC by heat, with citric acid, or with zeolite.
This page includes the world's most widely consumed psychoactive substances, ranging from coffee to psilocybin mushroom mycelium.
Psilocybin mushroom colonization: The colonization or mycelium stage of psilocybin mushroom growth contains much lower levels of the psychoactive compounds psilocybin and psilocin compared to the mature mushroom fruiting bodies. However, the mycelium can still be potent enough for medicinal or therapeutic use. The legal status of psilocybin mushrooms and their various growth stages is ambiguous and varies widely across jurisdictions. While spores and cultivation kits for these fungi are generally permitted in most nations, the legal status becomes murkier as the mushrooms mature.
Example of legal status of psilocybin mushroom mycelium:
Legal
Chile
Mexico
Sweden
Illegal
US "If the mushroom spores (or any other material) do not contain psilocybin or psilocin (or any other controlled substance or listed chemical), the material is considered not controlled", and "if at any time the material contains a controlled substance such as psilocybin or psilocin (for example, upon germination), the material would be considered a controlled substance under the CSA" - DEA’s Drug & Chemical Evaluation Section Chief Terrence Boos.
