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'''Cotinine''' (also known as '''(5S)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one''' and '''Scotine''') is the main metabolite of [[nicotine]].
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{{SummarySheet}}
{{SubstanceBox/Cotinine}}
'''Cotinine''' (also known as '''(5S)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one''' and '''Scotine''') is a [[stimulant]] alkaloid and the main metabolite of [[nicotine]].
==Pharmacology==
==Pharmacology==
Cotinine binds to many nicotinic [[acetylcholine]] receptors at a lower potency than nicotine.
Cotinine binds to many nicotinic [[acetylcholine]] receptors at a lower potency than nicotine. It has a biological half-life of 20 hours.{{citation needed|date=November 2020}}
===Metabolism===
Cotinine has a biological half-life of 20 hours.
==Subjective effects==
==Subjective effects==
{{EffectStub}}
{{Preamble/SubjectiveEffects}}
{{Preamble/SubjectiveEffects}}
{{effects/base
===Physical effects===
|{{effects/physical|
*'''[[Effect::Stimulation]]'''
*'''[[Effect::Stimulation]]'''
*'''[[Effect::Appetite suppression]]'''
*'''[[Effect::Appetite suppression]]'''
}}
===Cognitive effects===
|{{effects/cognitive|
*'''[[Effect::Focus enhancement]]'''
*'''[[Effect::Focus enhancement]]'''
*'''[[Effect::Memory enhancement]]'''
*'''[[Effect::Memory enhancement]]'''
*'''[[Effect::Motivation enhancement]]'''
*'''[[Effect::Motivation enhancement]]'''
*'''[[Effect::Thought acceleration]]'''
*'''[[Effect::Thought acceleration]]'''
}}
}}
==See also==
==See also==
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[[Category:Stimulant]]
[[Category:Stimulant]]
[[Category:Pyrrolidine]]
[[Category:Pyrrolidine]]
[[Category:Stub]]
[[Category:Proofread]]
Latest revision as of 22:19, 13 November 2020
This article is in the 'Talk' namespace because it is an unfinished draft. This section is used to host drafts for unpublished articles as well as discussions for published ones. If you'd like to use this area to discuss this draft, please do so in the 'Discussion' section at the very bottom of the page. This notice will be removed once this draft has been approved for publication by an administrator.
It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.