Depression
Depression can be described as a state of low mood and aversion to activity that can affect a person's general sense of well-being in a negative manner. Depressed people often feel sad, anxious, empty, hopeless, worried, helpless, worthless, guilty, irritable, hurt, or restless. They may have problems concentrating, remembering details, or making decisions and may contemplate or attempt to commit suicide.
In the context of hallucinogen usage, this effect is triggered by certain substances as a temporary effect which can be considered as the polar opposite of cognitive euphoria.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 2-Aminoindane
- 2-FA
- 2-FEA
- 2-FMA
- 3,4-CTMP
- 3-FA
- 3-FEA
- 3-FMA
- 3-FPM
- 3-MMC
- 4-FA
- 4-FMA
- 4F-EPH
- 4F-MPH
- 5-APB
- 5-MAPB
- 6-APB
- 6-APDB
- A-PHP
- A-PVP
- Alcohol
- Amphetamine
- Baclofen
- Benzydamine
- Butylone
- Caffeine
- Cocoa
- Cyclazodone
- Datura
- Desoxypipradrol
- Dichloropane
- Diphenhydramine
- ETH-CAT
- Ephylone
- Ethylone
- Ethylphenidate
- F-Phenibut
- Fenethylline
- Hexedrone
- Isopropylphenidate
- Lisdexamfetamine
- MCPP
- MDA
- MDAI
- MDEA
- MDMA
- MDPV
- Meclofenoxate
- Mephedrone
- Methcathinone
Experience reports
Anecdotal reports which describe this effect within our experience index include:
- Experience:30mg - Psychostimulant egodeath
- Experience:Hawaiian Baby Woodrose (5 seeds) - Five seeds from hell