DOx

The general structure for a DOx compound

DOx refers to a group of psychedelic amphetamines originally synthesized and studied by Alexander Shulgin in his investigation of psychoactive phenethylamines. Shulgin created most of these substances in the 1970s and later published his findings in his book PiHKAL. The DOx chemicals are highly potent, dose-sensitive, long-lasting and are considered more intense and difficult to use than their counterpart 2C-x family, with strong visuals and an intense body load that can be accompanied by a strong sense of stimulation.

List of DOx compounds

Compound	R4	Structure
ALEPH	SCH3
ALEPH-2	SCH2CH3
ALEPH-7	SCH2CH2CH3
DOB	Br
DOC	Cl
DOE	CH2CH3
DOI	I
DOM	CH3

Health effects, potential addiction and tolerance

This toxicity and harm potential section is a stub. As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.

The DOx chemicals, as with many other serotonergic psychedelics, should not be taken in combination with SSRIs (selective serotonin reuptake inhibitors) or tricyclic antidepressants in general to avoid serotonin syndrome, a potentially life-threatening condition in which an abundance of serotonin builds up past the body's ability to catabolize it, causing many physical and cognitive health problems.

Legal issues

• USA: In the US, some of the DOx chemicals are listed as Schedule I substances and all others under the Federal Analog Act.
• Australia: Australia has a blanket ban over all substituted phenethylamines including the entire DOx family.
• Switzerland: DOM, DOB and DOE are illegal to possess, produce and sell.

See also

• Responsible use
• 2C-x
• 25x-NBOMe
• Psychedelics
• Phenethylamines