DOx

DOx refers to a group of amphetamines originally studied by Alexander Shulgin. Most of the DOx chemicals were first synthesized by Shulgin in the 1970s and later published in his book PiHKAL. The DOx chemicals are highly potent and dose-sensetive and are considered more intense than their counterpart 2C-x family.

Examples

• DOB
• DOC
• DOI
• DOM

Health effects, potential addiction and tolerance

The DOx chemicals, as with many other serotonergic psychedelics, should not be taken in combination with SSRIs (selective serotonin reuptake inhibitors) or tricyclic antidepressants in general to avoid serotonin syndrome, a potentially life-threatening condition in which an abundance of serotonin is built up the body, causing many physical and cognitive health problems.

Legal issues

• USA: In the US, the DOx chemicals are listed as Schedule I substances under the American Food and Drug Administration Safety and Innovation Act of 2012 and under the Federal Analog Act.
• Australia: Australia has a blanket ban over all substituted phenethylamines including the entire 2C-X family.
• Switzerland: 2C-B, 2C-I, 2C-T-2 and 2C-T-7 are illegal to possess, produce and sell.

See also

• Responsible use
• 2C-x
• 25x-NBOMe
• Psychedelics
• Phenethylamines