Benzydamine

Benzydamine
Chemical Nomenclature
Common names	Benzydamine, Tantum Verde
Substitutive name	Benzydamine
Systematic name	3-(1-Benzyl-1H-indazol-3-yloxy)-N,N-dimethylpropan-1-amine
Class Membership
Psychoactive class	Deliriant / Stimulant
Chemical class	Indazole
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Threshold 150 mg Light 300 - 500 mg Common 500 - 1000 mg Strong 1000 - 2000 mg Heavy 2000 mg + Duration Total 5 - 8 hours Onset 20 - 60 minutes Peak 3 - 6 hours Offset 3 - 8 hours After effects 24 - 72 hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Interactions

Summary sheet: Benzydamine

Benzydamine (also known as Difflam or Tantum Verde) is a topical anaesthetic of the indazole alkaloid chemical class. It is sometimes found in small doses in over-the-counter products used to treat sore throats. In Germany and Poland, it is sold as a vaginal douching agent under the brand name Tantum Rosa. This product is also easily accessible across the world through the use of online stores such as eBay.

Alternatively, benzydamine can be used as a powerful psychoactive hallucinogen for recreational purposes. In high doses, it acts as a unique deliriant and CNS stimulant. Such use, particularly among teenagers, has been reported in Poland, Brazil and Romania.

Chemistry

Benzydamine, or 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine, is a synthetic benzyl-indazole molecule. Benzydamine contains a benzene and pyrazole ring fused to form a bicyclic indazole group. A benzyl substituent C₆H₅CH₂- is bound to R₁ of the indazole ring. This indazole ring is also substituted at R₃ with an ether chain consisting of the oxygen group bonded to a propyl amine chain. The terminal amine R_N of this structure is substituted with two methyl groups (dimethyl). Benzydamine is produced as a hydrochloride salt.

Pharmacology

Benzydamine is a locally acting nonsteroidal anti-inflammatory drug with local anaesthetic and analgesic properties. Unlike other NSAIDs, it does not inhibit cyclooxygenase or lipooxygenase and is not ulcerogenic.

In terms of the pharmacology behind its hallucinogenic effects, this aspect of benzydamine remains unstudied and is subject to much speculation.

Subjective effects

This subjective effects section is a stub. As such, it is still in progress and may contain incomplete or wrong information. You can help by expanding or correcting it.

Physical effects

• Stimulation - Insomnia and residual stimulation lasting up to 72 hours after the initial experience may occur on this substance.
• Abnormal heartbeat
• Tactile suppression
• Increased heart rate

Visual effects

• External hallucinations (autonomous entities; settings, sceneries, and landscapes; alterations in perspective and scenarios and plots)
• Visual acuity suppression
• Drifting
• Visual haze
• Geometry

Cognitive effects

• Anxiety
• Euphoria
• Depression
• Time distortion
• Thought acceleration
• Delusions

Auditory effects

• Hallucinations
• Distortion

Toxicity and harm potential

Main article: Research chemicals § Toxicity and harm potential

The vaginal douching agents such as Tantum Rosa and other products consistently contain large amounts of salt which, if consumed, can cause serious kidney damage.

The toxicity and long-term health effects of recreational benzydamine use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because benzydamine is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried benzydamine suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

Extraction

Benzydamine is usually extracted from Tantum Rosa douching agents which are available online. In order to consume the substance safely, one must first remove the dangerous levels of salt contained within the sachet. This can be done by dissolving the substance in a small amount of water (25ml/sachet) and filtering through a paper filter. The salt will dissolve in water to create a saturated solution. The powder left on the filter can then be dried and consumed by either eating or dissolving it in liquid and drinking. It is not advised to drink the water used to dissolve the salt.

Legal issues

Benzydamine is legal and available in over-the-counter preparations in most parts of the world.

• 
  Difflam spray
• 
  Tantum Rosa
• 
  Difflam mouth gel

See also

• Responsible use
• Deliriants
• Stimulants
• Diphenhydramine
• DXM

External links

• Benzydamine (Wikipedia)
• Benzydamine (Taimapedia)
• Benzydamine (Bluelight)
• Benzydamine (Drugs Forum)
• Benzydamine (Reddit)