5-MeO-DiBF

5-MeO-DiBF
Chemical Nomenclature
Common names	5-MeO-DiBF
Systematic name	2-(5-Methoxy-1-benzofuran-3-yl)-N,N-diisopropyllethanamine
Class Membership
Psychoactive class	Psychedelic
Chemical class	Benzofuran
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Threshold 20 mg Light 50 - 80 mg Common 80 - 110 mg Strong 110 - 140 mg Heavy 140 mg + Duration Total 4 - 6 hours Peak 30 - 60 minutes DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Interactions

Summary sheet: 5-MeO-DiBF

5-MeO-DiBF (2-(5-Methoxy-1-benzofuran-3-yl)-N,N-diisopropyllethanamine) is a psychedelic drug in a class of compounds commonly known as benzofurans. It has structural and pharmacodynamic properties similar to the drug known as 5-MeO-DiPT.

This compound has little to no history of human usage prior to its September 2015 release as a grey area compound on the online research chemical market.

Chemistry

5-MeO-DiBF, or 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-diisopropyllethanamine, is a synthetic heterocyclic alkaloid molecule of the benzofuran class. Benzofuran is a bicyclic structure formed by the fusion of a benzene ring and a furan ring, a five member aromatic ring containing an oxygen substituent. The structure of 5-MeO-DiBF is comprised of its benzofuran group attached at R₃ to an amino group via an ethyl side chain. It is substituted at R₅ of the benzofuran heterocycle with a methoxy (MeO) functional group CH₃O−; it also contains two isopropyl chains bound to the terminal amine R_N of its tryptamine backbone (DiBF).

The benzofuran group of 5-MeO-DiBF is closely related in structure to the indole found in tryptamines; benzofuran contains an oxygen group at the same location that indole contains a nitrogen. As such, 5-MeO-DiBF is closely related in structure to the psychedelic tryptamine 5-MeO-DiPT. 5-MeO-DiBF is the benzofuran analogue of 5-MeO-DiPT.

Pharmacology

Main article: Serotonergic psychedelic

5-MeO-DiBF likely acts as a 5-HT_2A partial agonist. The psychedelic effects are believed to come from its efficacy at the 5-HT_1A and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

This compound is several times less potent as a serotonin agonist than 5-MeO-DiPT. It has relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical effects

• Increased heart rate
• Muscle spasms
• Nausea - This effect is particularly mild compared to other psychedelics.
• Perception of decreased weight
• Pupil dilation
• Spontaneous tactile sensations - The "body high" of 5-MeO-DiBF can be described as a motionless, constant, sharp and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the come up and hits its limit once the peak has been reached.
• Stimulation
• Tactile enhancement
• Temperature regulation suppression

Cognitive effects

The head space of 5-MeO-DiBF is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high doses.

The total sum of these cognitive components (regardless of the setting) generally includes:

• Analysis enhancement
• Conceptual thinking
• Emotion enhancement
• Increased libido
• Increased music appreciation
• Memory suppression
  • Ego death
• Novelty enhancement
• Personal bias suppression
• Rejuvenation
• Thought acceleration
• Thought connectivity
• Time distortion
• Wakefulness

Visual effects

Enhancements

• Colour enhancement
• Pattern recognition enhancement
• Acuity enhancement

Distortions

• Drifting (melting, flowing, breathing and morphing) - In comparison to other psychedelics, this effect can be described as simplistic, slow and smooth in motion, static in appearance and unrealistic in style.
• Colour shifting
• Symmetrical texture repetition
• Tracers

Geometry

The visual geometry that is present throughout the experience can be described as more similar in appearance to that of 5-MeO-DALT or AMT than that of LSD, 2C-B or 2C-I. It can be comprehensively described as unstructured in its organization, synthetic in geometric style, intricate in complexity, small in size, slow and smooth in motion, colourful in scheme, glossy in colour, equally blurred and sharp in its edges and equally rounded and angular in its corners. It gives off a synthetic feel that is less impressive than most of the "classical" psychedelics at any level. It has yet to be confirmed whether this compound results in either level 8A or level 8B geometry at heavy doses.

Auditory effects

• Enhancements
• Distortions
• Hallucinations

Toxicity and harm potential

Main articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational 5-MeO-DiBF use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 5-MeO-DiBF is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 5-MeO-DiBF suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

5-MeO-DiBF is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of 5-MeO-DiBF are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 5-MeO-DiBF presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 5-MeO-DiBF all psychedelics will have a reduced effect.

Legal issues

This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it.

5-MeO-DiBF is currently thought to be a legal grey area drug in many parts of the world. However, although it is easily accessible through the use of online research chemical vendors, this does not guarantee anyone to be immune from legal prosecution should they be found in possession of this substance as the legality is likely to vary from country to country.

• United Kingdom - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.

See also

• Responsible use
• Psychedelic
• Tryptamine
• 5-MeO-MiPT
• 5-MeO-DiPT
• 5-MeO-DMT

External links

• 5-MeO-DiBF (Wikipedia)
• 5-MeO-DiBF (Tripsit)
• 5-MeO-DiBF (UK Chemical Research)
• 5-MeO-DiBF (BlueLight)