Addiction suppression
Template:Proofread Addiction suppression can be described as the experience of a total or partial removal of a psychological addiction to a specific substance. This can occur as an effect which lasts long after the compound wears off or it can last only while it is still active. Addiction suppression is a rare component and is most commonly associated with psychedelics[1], psilocin[2], LSD[3] and ibiogaine[4] and N-Acetylcysteine.[5]
In terms of psychedelics, this effect seems to be triggered by a combination of analysis enhancement, personal bias suppression and general introspection. However, NAC seems to have a more direct effect that occurs as a result of its action on glutaminergic and dopaminergic pathways which is thought to reverse brain functions which have become disturbed by heavy drug addiction.[6]
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 1cP-LSD
- 3-MeO-PCP
- 5-MeO-DMT
- Ayahuasca
- Baclofen
- Cannabidiol
- Citicoline
- Clonidine
- Ibogaine
- Kava
- Ketamine
- LSD
- N-Acetylcysteine
- Psilocin
- Psilocybin mushrooms
- Theanine
See also
References
- ↑ Psychedelics: entering a new age of addiction therapy | http://www.pharmaceutical-journal.com/news-and-analysis/features/psychedelics-entering-a-new-age-of-addiction-therapy/20066899.article#fn_link_1
- ↑ Pilot Study of the 5-HT2AR Agonist Psilocybin in the Treatment of Tobacco Addiction | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286320/
- ↑ Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials | http://www.ncbi.nlm.nih.gov/pubmed/22406913
- ↑ Mind-altering drug could offer life free of heroin (New Scientist) | https://www.newscientist.com/article/mg21929313-900-mind-altering-drug-could-offer-life-free-of-heroin/
- ↑ Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking | http://www.ncbi.nlm.nih.gov/pubmed/16000629
- ↑ Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking | http://www.ncbi.nlm.nih.gov/pubmed/16000629