2-FMA
| 2-FMA | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical Nomenclature | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Common names | 2-FMA | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Substitutive name | 2-Fluoromethamphetamine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Systematic name | 1-(2-Fluorophenyl)-N-methylpropan-2-amine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Class Membership | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Psychoactive class | Stimulant | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Chemical class | Amphetamine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Routes of Administration | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Alcohol | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GHB | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GBL | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Opioids | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cannabis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Caffeine | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Ketamine | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Methoxetamine | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Psychedelics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cocaine | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DXM | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PCP | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 25x-NBOMe | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 2C-T-x | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 5-MeO-xxT | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| DOx | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| aMT | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| MAOIs | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
This article is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it. |
2-Fluoromethamphetamine (2-FMA) is a substituted amphetamine with stimulant and nootropic effects. It is rarely found on the streets but commonly sold as a grey area research chemical through online vendors.[1][2]
Chemistry
Pharmacology
Although 2-FMA has not been formally studied, it is safe to assume that just like other substituted amphetamines, it most likely acts as both a dopamine and norepinephrine reuptake inhibitor. This means it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters in the brain, by binding to, and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft. This allows dopamine and norepinephrine to accumulate within the brain, resulting in stimulating and euphoric effects.
Subjective effects
In comparison to other substituted amphetamines, 2-FMA is particularly free of side effects such as nausea, high blood pressure and anxiety. It is considered to be extremely functional and an effective nootropic for performing tasks general productivity of any sort.
The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely if ever occur all at once but heavier dosages will increase the chances and are more likely to induce a full range of effects.
Physical effects
Cognitive effects
- Thought acceleration
- Focus enhancement
- Wakefulness
- Information processing enhancement
- Motivation enhancement
Toxicity and Harm Potential
The toxicity and long term health effects of recreational 2-FMA use does not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 2-FMA is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychedelic community who have tried 2-FMA suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).
Tolerance and Addiction Potential
Tolerance develops rapidly with repeated usage, so periods of extended use require increasing doses of the drug in order to achieve the same effect. Addiction is a serious risk with heavy recreational use of any substituted amphetamine and compulsive re-dosing is extremely common.
Psychosis
Abuse of amphetamines at high dosages for prolonged periods of time can result in a stimulant psychosis that may present with a variety of symptoms (e.g., paranoia, hallucinations, delusions).[3] A Cochrane Collaboration review on treatment for amphetamine, dextroamphetamine, and methamphetamine abuse-induced psychosis states that about 5–15% of users fail to recover completely.[4][5] The same review asserts that, based upon at least one trial, antipsychotic medications effectively resolve the symptoms of acute amphetamine psychosis.[6] Psychosis very rarely arises from therapeutic use.[7][8]
Legal Issues
2-FMA is currently a grey area compound within all parts of the world. This means that it is not known to be specifically illegal within any countries but that people may still be charged for its possession under certain circumstances.
See Also
References
- ↑ Isomeric fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs). | http://www.ncbi.nlm.nih.gov/pubmed/15639609
- ↑ Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, alpha-phthalimidopropiophenone and N-ethylcathinone | http://www.ncbi.nlm.nih.gov/pubmed/20074881
- ↑ Treatment for amphetamine psychosis | http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003026.pub3/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+Saturday%2C+15+March+from+10%3A00-12%3A00+GMT+%2806%3A00-08%3A00+EDT%29+for+essential+maintenance
- ↑ Treatment for amphetamine psychosis | http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003026.pub3/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+Saturday%2C+15+March+from+10%3A00-12%3A00+GMT+%2806%3A00-08%3A00+EDT%29+for+essential+maintenance
- ↑ Hofmann FG (1983). A Handbook on Drug and Alcohol Abuse: The Biomedical Aspects (2nd ed.). New York: Oxford University Press. p. 329. ISBN 9780195030570.
- ↑ Treatment for amphetamine psychosis | http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003026.pub3/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+Saturday%2C+15+March+from+10%3A00-12%3A00+GMT+%2806%3A00-08%3A00+EDT%29+for+essential+maintenance
- ↑ Stimulant Misuse: Strategies to Manage a Growing Problem | http://www.acha.org/prof_dev/ADHD_docs/ADHD_PDprogram_Article2.pdf
- ↑ http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021303s026lbl.pdf