Bronchodilation

Some psychostimulant drugs that have an amphetamine-like mode of action, such as amphetamine,[1] methamphetamine, and cocaine,[2] have bronchodilating effects and were used often for asthma due to the lack of effective β2-agonists for use as bronchodilator, but are now rarely, if ever, used medically for their bronchodilation effect. Caffeine is also an effective bronchodilator; In clinical tests on adults with athsma, at fairly low doses (5mg/kg of body weight), caffeine has been shown to provide a small improvement in lung function, such that it needs to be controlled for in diagnostic tests.