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Template:SubstanceBox/Buprenorphine

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Revision as of 03:32, 10 January 2022 by >Shayanzarrin (It is common knowledge that sublingual absorption of buprenorphine lasts for 24 hours, and that peak effects are reached in 90 minutes)
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SubstanceBox/Buprenorphine
Chemical Nomenclature
Common names Buprenex, Subutex, Butrans, Cizdol, Addnok, Transtec
Systematic name (2S)-2-[(5R,6R,7R,14S)-9α-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3,3-dimethylbutan-2-ol
Class Membership
Psychoactive class Opioid
Chemical class Morphinan
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.





Sublingual
Dosage
Bioavailability 30%[1]
Threshold <0.3 mg
Light 0.3 - 0.6 mg
Common 0.6 - 1.3 mg
Strong 1.3 - 2.4 mg
Heavy 2.4 mg +
Duration
Total 18-24 hours
Onset 40 - 80 minutes
Peak 1.5-2 hours
After effects 1 - 3 days
Insufflated
Dosage
Bioavailability 48%[2]
Threshold < 0.2 mg
Light 0.2 - 0.4 mg
Common 0.4 - 0.8 mg
Strong 0.8 - 1.5 mg
Heavy 1.5 mg +
Duration
Total 8 - 14 hours
Onset 30 - 60 minutes
Peak 4 - 8 hours
After effects 1 - 3 days






DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

  1. Bioavailability of sublingual buprenorphine. (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/9048270
  2. The systemic availability of buprenorphine administered by nasal spray. (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/2576057