Talk:Cabergoline
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Cabergoline is a chemical of the lysergamide and ergopeptine classes of drugs. It is a derivative of LSD or more specifically AL-LAD and shares many effects with related, non-psychedelic compounds such as ergotamine, ergonovine or lisuride. It is occasionally prescribed to treat symptoms of high prolactin levels and managing Parkinson's disease.
Cabergoline is not predominantly psychedelic but rather excerts its effects strongest at the Dopamine D2 receptor as an agonist and comparitavely little on the Serotonin 5-HT2A receptor, as a partial agonist.
Cabergoline has little recreational value exclusively due to its unique property of reducing or eliminating the male refractory period, thereby allowing men to experience multiple ejaculatory orgasms in rapid succession.[1][2]
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- ↑ Krüger TH, Haake P, Haverkamp J, et al. (December 2003). "Effects of acute prolactin manipulation on sexual drive and function in males". Journal of Endocrinology. 179 (3): 357–65. CiteSeerX 10.1.1.484.4005. doi:10.1677/joe.0.1790357. PMID 14656205.
- ↑ Hollander, Adam B.; Pastuszak, Alexander W.; Lipshultz, Larry I. (2016). "Cabergoline in the Treatment of Male Orgasmic Disorder—A Retrospective Pilot Analysis". Journal of Sexual Medicine. 4 (4): e28–e33. doi:10.1016/j.esxm.2015.09.001. PMC 4822480. PMID 26944776.