This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.
DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
N-Methyl-N-isopropyltryptamine (also known as MiPT) is an obscure synthetic psychedelic substance of the tryptamine chemical class that reportedly produces mild and indistinct psychedelic effects when administered.
MiPT was first synthesized and documented by Alexander Shulgin in his book TiHKAL ("Tryptamines I Have Known and Loved"). In it, he lists the dosage as 10 - 25 mg (oral) with a 3 - 4 hour duration. The documented reports vary in their description and generally tend to describe it as more of a mild sensory amplifier than a substance capable of the profound sensory distortions and alterations psychedelics are known to produce.[1]
Today, MiPT remains relatively uncommon and is either used recreationally or as an entheogenic substance. It is almost exclusively acquired as a grey-area research chemical through online vendors. Very little data exists about the pharmacological properties, metabolism, and toxicity of MiPT, and it has little history of human usage. Because of this, it is highly advised to approach this poorly understood psychedelic substance with the proper amount of precaution and harm reduction practices if choosing to use it.
Like with most psychedelic tryptamines, MiPT is thought to act principally as a 5-HT2Apartial agonist. The psychedelic effects are believed to come from MiPT's binding efficacy at the 5-HT2A receptors.
However, the role of these interactions and how it results in the psychedelic experience continues to remain elusive.
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
The sensory effects of MiPT are said to be similar to those of DiPT but with less intensity at the same dose, and without the same bias towards producing auditory distortions.
The cognitive effects of MiPT are reported to be mild for a psychedelic, yet relatively prominent compared to the minor sensory alterations it produces. Rather than producing distinct sensory distortions, it is reported instead to act as a mild sensory amplifier, with an emphasis on altering perceptual and cognitive patterns in a traditional psychedelic fashion.
Enhancements - MiPT has been reported to notably enhance auditory sensation, which stands in contrast to the relatively weak visual changes it produces.
There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:
The toxicity and long-term health effects of recreational MiPT use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because MiPT is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried MiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.
MiPT is not habit-forming and the desire to use it can actually decrease with regular consumption. Like with most psychedelics, it is most often thought to be self-regulating.
Tolerance to the effects of MiPT are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). MiPT presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of MiPT all psychedelics will have a reduced effect.
Legality
Due to its relative obscurity, the possession and sale of MiPT is unscheduled in most countries.
United Kingdom - MiPT is a Class A drug in the United Kingdom as a result of the tryptamine catch-all clause.[2]
United States - MiPT is unscheduled in the United States. It may be considered an analogue of DMT, which is a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.[citation needed]
