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{{SubstanceBox/2-C-T7}}
{{SubstanceBox/2-C-T7}}


'''2,5-Dimethoxy-4-propylthiophenethylamine''' (abbreviated '''2C-T-7'''; also known as '''Blue Mystic''' and '''7th Heaven''' among others) is a synthetic [[Psychoactive class::psychedelic]] substance of the [[Chemical class::phenethylamine]] chemical class that produces [[psychedelic]] and [[entactogenic]] effects when [[routes of administration|administered]]. It is a member of the [[2C-x]] family of psychedelic phenethylamines, all of which are derivatives of [[mescaline]].
'''2,5-Dimethoxy-4-propylthiophenethylamine''' (also known as '''2C-T-7''', '''Blue Mystic''' and '''7th Heaven''', among others) is a synthetic [[Psychoactive class::psychedelic]] substance of the [[Chemical class::phenethylamine]] chemical class that produces [[psychedelic]] and [[entactogenic]] effects when [[routes of administration|administered]]. It is a member of the [[2C-x]] family of psychedelic phenethylamines, all of which are derivatives of [[mescaline]].


2C-T-7 was first synthesized by [[Alexander Shulgin]] and documented in his book [[PiHKAL]] ("Phenethylamines I Have Known and Loved").<ref>https://erowid.org/library/books_online/pihkal/pihkal.shtml | [[PiHKAL]] </ref>
2C-T-7 was first synthesized by [[Alexander Shulgin]] and documented in his book [[PiHKAL]] ("Phenethylamines I Have Known and Loved").<ref>https://erowid.org/library/books_online/pihkal/pihkal.shtml | [[PiHKAL]] </ref>
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==Subjective effects==
==Subjective effects==
{{Preamble/SubjectiveEffects}}
{{Preamble/SubjectiveEffects}}
===Physical effects===
{{effects/base
*'''[[Effect::Stimulation]]''' - In terms of its effects on the physical energy levels of the tripper 2C-T-7 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other [[phenethylamines]] such as [[2C-B]], [[2C-E]] and [[2C-P]].  
 
|{{effects/physical|
*'''[[Effect::Stimulation]]''' - In terms of its effects on the physical energy levels of the user, 2C-T-7 is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of other [[phenethylamines]] such as [[2C-B]], [[2C-E]] and [[2C-P]].
*'''[[Effect::Spontaneous physical sensations]]''' - The "body high" of 2C-T-7 is intense, but in comparison to [[2C-E]] or [[2C-B]], it can be considered mild though is still capable of becoming very powerful and highly physically euphoric. It is similar yet distinct from the "body high" experienced on [[2C-E]], [[2C-B]], and [[LSD]]. The sensation itself can be described as intense and will manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves. 
*'''[[Effect::Bodily control enhancement]]''' - Although this component is capable of manifesting itself in a distinct and noticeable fashion, for most users it does not generally seem to be as apparent or intense as the same component found within [[LSD]] and [[2C-B]].
*'''[[Effect::Bodily control enhancement]]''' - Although this component is capable of manifesting itself in a distinct and noticeable fashion, for most users it does not generally seem to be as apparent or intense as the same component found within [[LSD]] and [[2C-B]].
*'''[[Effect::Changes in felt bodily form]]'''
*'''[[Effect::Changes in felt bodily form]]'''
*'''[[Effect::Tactile enhancement]]'''
*'''[[Effect::Tactile enhancement]]'''
*'''[[Effect::Excessive yawning]]'''
*'''[[Effect::Temperature regulation suppression]]'''
*'''[[Effect::Spatial disorientation]]'''
**'''[[Effect::Increased bodily temperature]]'''
*'''[[Effect::Pupil dilation]]'''
*'''[[Effect::Watery eyes]]'''
 
===Uncomfortable physical side effects===
*'''[[Effect::Abnormal heartbeat]]'''
*'''[[Effect::Abnormal heartbeat]]'''
*'''[[Effect::Dehydration]]'''
*'''[[Effect::Dehydration]]'''
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*'''[[Effect::Muscle spasms]]'''
*'''[[Effect::Muscle spasms]]'''
*'''[[Effect::Muscle cramps]]'''
*'''[[Effect::Muscle cramps]]'''
*'''[[Effect::Nausea]]''' -  Mild to extreme nausea is commonly reported when consumed in moderate to high dosages, and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.
*'''[[Effect::Nausea]]''' -  Mild to extreme nausea is commonly reported when consumed in moderate to high dosages, and either passes once the user has vomited or gradually fades by itself as the peak sets in.
*'''[[Effect::Stomach bloating]]'''
*'''[[Effect::Stomach bloating]]'''
*'''[[Effect::Stomach cramps]]'''
*'''[[Effect::Stomach cramps]]'''
*'''[[Effect::Teeth grinding]]'''
*'''[[Effect::Teeth grinding]]'''
*'''[[Effect::Temperature regulation suppression]]'''
*'''[[Effect::Excessive yawning]]'''
 
*'''[[Effect::Pupil dilation]]'''
===Tactile effects===
*'''[[Effect::Watery eyes]]'''
*'''[[Effect::Spontaneous physical sensations]]''' - The "body high" of 2C-T-7 is intense, but in comparison to [[2C-E]] or [[2C-B]], it can be considered mild though is still capable of becoming very powerful and highly physically euphoric. It is similar yet distinct from the "body high" experienced on [[2C-E]], [[2C-B]], and [[LSD]]. The sensation itself can be described as intense and will manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.
*'''[[Effect::Tactile enhancement]]'''
*'''[[Effect::Tactile hallucinations]]'''
 
===Cognitive effects===
The head space of 2C-T-7 is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.
 
The total sum of these cognitive components regardless of the setting generally includes:


*'''[[Effect::Emotionality enhancement]]'''
}}
*'''[[Effect::Thought acceleration]]'''
{{effects/visual|
*'''[[Effect::Novelty enhancement]]'''
*'''[[Effect::Time distortion]]'''
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Analysis enhancement]]'''
*'''[[Effect::Personal bias suppression]]'''
*'''[[Effect::Conceptual thinking]]'''
*'''[[Effect::Memory suppression]]'''
**'''[[Effect::Ego death]]'''
*'''[[Effect::Immersion enhancement]]'''
*'''[[Effect::Thought loops]]'''
*'''[[Effect::Feelings of interdependent opposites]]'''
*'''[[Effect::Delusions]]'''
*'''[[Effect::Unity and interconnectedness]]'''
*'''[[Effect::Wakefulness]]'''


===Visual effects===
====[[Visual effects - Psychedelics#Enhancements|Enhancements]]====
====[[Visual effects - Psychedelics#Enhancements|Enhancements]]====
*'''[[Effect::Visual acuity enhancement]]'''
*'''[[Effect::Visual acuity enhancement]]'''
Line 107: Line 83:
*'''[[Effect::Internal hallucinations]]''' (''[[effect::autonomous entities]]''; ''[[effect::settings, sceneries, and landscapes]]''; ''[[effect::alterations in perspective]]'' and ''[[effect::scenarios and plots]]'') - This effect is very consistent in dark environments at appropriately high dosages. They can be comprehensively described through their [[Visual_effects:_Internal_hallucinations#Variations|variations]] as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, [[Geometry|geometry]]-based in style and almost exclusively of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental nature in their overall theme.
*'''[[Effect::Internal hallucinations]]''' (''[[effect::autonomous entities]]''; ''[[effect::settings, sceneries, and landscapes]]''; ''[[effect::alterations in perspective]]'' and ''[[effect::scenarios and plots]]'') - This effect is very consistent in dark environments at appropriately high dosages. They can be comprehensively described through their [[Visual_effects:_Internal_hallucinations#Variations|variations]] as lucid in believability, interactive in style, new experiences in content, autonomous in controllability, [[Geometry|geometry]]-based in style and almost exclusively of a personal, religious, spiritual, science-fiction, fantasy, surreal, nonsensical or transcendental nature in their overall theme.


===Auditory effects===
}}
|{{effects/cognitive|
The head space of 2C-T-7 is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high dosages.
 
*'''[[Effect::Emotionality enhancement]]'''
*'''[[Effect::Thought acceleration]]'''
*'''[[Effect::Novelty enhancement]]'''
*'''[[Effect::Time distortion]]'''
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Analysis enhancement]]'''
*'''[[Effect::Personal bias suppression]]'''
*'''[[Effect::Conceptual thinking]]'''
*'''[[Effect::Memory suppression]]'''
**'''[[Effect::Ego death]]'''
*'''[[Effect::Immersion enhancement]]'''
*'''[[Effect::Thought loops]]'''
*'''[[Effect::Delusions]]'''
*'''[[Effect::Wakefulness]]'''
 
}}
{{effects/auditory|
*'''[[Effect::Auditory enhancement|Enhancements]]'''
*'''[[Effect::Auditory enhancement|Enhancements]]'''
*'''[[Effect::Auditory distortion|Distortions]]'''
*'''[[Effect::Auditory distortion|Distortions]]'''
*'''[[Effect::Auditory hallucinations|Hallucinations]]'''
*'''[[Effect::Auditory hallucinations|Hallucinations]]'''


}}
{{effects/transpersonal|
*'''[[Effect::Unity and interconnectedness]]'''
}}
}}
===Experience reports===
===Experience reports===
There are currently no anecdotal reports which describe the effects of this compound within our [[experience index]]. Additional experience reports can be found here:
There are currently no anecdotal reports which describe the effects of this compound within our [[experience index]]. Additional experience reports can be found here:
* [https://www.erowid.org/experiences/subs/exp_2CT7.shtml Erowid Experience Vaults: 2C-T-7]
* [https://www.erowid.org/experiences/subs/exp_2CT7.shtml Erowid Experience Vaults: 2C-T-7]


==Potentially dangerous interactions==
==Toxicity and harm potential==
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
There have been at least three reported deaths related to 2C-T-7 use as of August 2007, mainly at insufflated doses of 30 mg or more{{citation needed}} or combined with stimulants such as MDMA,{{citation needed}} as well as a number of very uncomfortably intense effects and hospitalizations due to the insufflation of 2C-T-7.<ref name="T74">2C-T-7 Overdoses & Delirium | https://www.erowid.org/chemicals/2ct7/2ct7_effects.shtml#overdose</ref>
 
It is strongly discouraged to administer 2C-T-7 non-orally because this can cause vomiting, numerous negative side effects, or death at high doses. In Erowid's Fall 2000 2C-T-7 survey, it was reported that the [[insufflation]] of 2C-T-7 resulted in more negative side effects than oral administration.{{citation needed}}
 
It is strongly recommended that one use [[responsible drug use|harm reduction practices]], such as [[volumetric dosing]], when using this substance to ensure the accurate administration of the intended dose.
 
===Tolerance and addiction potential===
2C-T-7 is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating.
 
Tolerance to the effects of 2C-T-7 are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 2C-T-7 presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 2C-T-7 all psychedelics will have a reduced effect.
 
===Dangerous interactions===
If 2C-T-7 does have [[MAOI]] effects as commonly speculated, this could indicate that 2C-T-7 is more likely to induce [[serotonin syndrome]] or general [[neurotransmitter]] overload (especially at high dosages) than other [[serotonergic psychedelic]]s.<ref>Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors:  Biological Activities, CoMFA Analysis, and Active Site Modeling | http://pubs.acs.org/doi/abs/10.1021/jm0493109</ref> This may make it dangerous to combine it with other [[MAOI]]s, [[stimulant]]s and certain substances which releases neurotransmitters such as [[serotonin]] or [[dopamine]]. These substances include but are not limited to:
If 2C-T-7 does have [[MAOI]] effects as commonly speculated, this could indicate that 2C-T-7 is more likely to induce [[serotonin syndrome]] or general [[neurotransmitter]] overload (especially at high dosages) than other [[serotonergic psychedelic]]s.<ref>Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors:  Biological Activities, CoMFA Analysis, and Active Site Modeling | http://pubs.acs.org/doi/abs/10.1021/jm0493109</ref> This may make it dangerous to combine it with other [[MAOI]]s, [[stimulant]]s and certain substances which releases neurotransmitters such as [[serotonin]] or [[dopamine]]. These substances include but are not limited to:
{|
{|
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|}
|}


==Toxicity and harm potential==
==Legality==
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
*'''Australia''' - In Australia, 2C-T-2 and 2C-T-7 are covered by the country's analog drug laws.{{citation needed}}
There have been at least three reported deaths related to 2C-T-7 use as of August 2007, mainly at insufflated doses of 30 mg or more{{citation needed}} or combined with stimulants such as MDMA,{{citation needed}} as well as a number of very uncomfortably intense effects and hospitalizations due to the insufflation of 2C-T-7.<ref name="T74">2C-T-7 Overdoses & Delirium | https://www.erowid.org/chemicals/2ct7/2ct7_effects.shtml#overdose</ref>
 
It is strongly discouraged to administer 2C-T-7 non-orally because this can cause vomiting, numerous negative side effects, or death at high doses. In Erowid's Fall 2000 2C-T-7 survey, it was reported that the [[insufflation]] of 2C-T-7 resulted in more negative side effects than oral administration.{{citation needed}}
 
It is strongly recommended that one use [[responsible drug use|harm reduction practices]], such as [[volumetric dosing]], when using this substance to ensure the administration of the intended dose.
 
===Tolerance and addiction potential===
2C-T-7 is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating.
 
Tolerance to the effects of 2C-T-7 are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 2C-T-7 presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 2C-T-7 all psychedelics will have a reduced effect.
 
==Legal issues==
*'''Brazil''' - Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.<ref>http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7</ref>
*'''Brazil''' - Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.<ref>http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7</ref>
*'''United Kingdom''' - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref>
*'''Canada:''' 2C-T-7 is considered Schedule III as it is a derivative of 2,5-dimethoxyphenethylamine.<ref>Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28</ref>
*'''United States''' - On September 20, 2002, 2C-T-7 was classified as a Schedule I substance in the United States by an emergency ruling by the DEA. On March 18, 2004, the DEA published a final rule in the Federal Register which permanently placed 2C-T-7 in Schedule I.
*'''China''' - As of October 2015 2C-T-7 is a controlled substance in China.<ref>{{cite web | url=http://www.sfda.gov.cn/WS01/CL0056/130753.html | title=关于印发《非药用类麻醉药品和精神药品列管办法》的通知 | publisher=China Food and Drug Administration | date=27 September 2015 | language=Chinese | accessdate=1 October 2015}}</ref>
*'''Germany''' - 2C-T-7 is scheduled in Germany.{{citation needed}}
*'''Latvia''' - 2C-T-7 is a Schedule I controlled substance in Latvia.<ref>Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086</ref>
*'''Latvia''' - 2C-T-7 is a Schedule I controlled substance in Latvia.<ref>Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086</ref>
*'''Germany''' - 2C-T-7 is scheduled in Germany.
*'''Netherlands''' - The Netherlands was the first country in the world to ban 2C-T-7 after being sold in smart shops for a short period. After 2C-T-2 was first banned, 2C-T-7 quickly appeared on the market but was soon banned as well. 2C-T-7 is a list I drug of the Opium Law.{{citation needed}}
*'''Australia''' - In Australia, 2C-T-2 and 2C-T-7 are covered by the country's analog drug laws.
*'''Sweden''' - The drug is Schedule I in Sweden.<ref>http://www.lakemedelsverket.se/upload/lvfs/LVFS_2004-3.pdf</ref> 2C-T-7 was first classified as a health hazard under the act "Lagen om förbud mot vissa hälsofarliga varor" (translated as "the Act on the Prohibition of Certain Goods Dangerous to Health") that made it illegal to sell or possess as of April 1, 1999.{{citation needed}}
*'''Canada:''' 2C-T-7 is considered Schedule III as it is a derivative of 2,5-dimethoxyphenethylamine.<ref>Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28</ref>
*'''Netherlands''' - The Netherlands was the first country in the world to ban 2C-T-7 after being sold in smart shops for a short period. After 2C-T-2 was first banned, 2C-T-7 quickly appeared on the market but was soon banned as well. 2C-T-7 is a list I drug of the Opium Law.
*'''Sweden''' - The drug is Schedule I in Sweden.<ref>http://www.lakemedelsverket.se/upload/lvfs/LVFS_2004-3.pdf</ref> 2C-T-7 was first classified as a health hazard under the act "Lagen om förbud mot vissa hälsofarliga varor" (translated as "the Act on the Prohibition of Certain Goods Dangerous to Health") that made it illegal to sell or possess as of April 1, 1999.
*'''Switzerland:''' Possession, production and sale is illegal.<ref>http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html</ref>
*'''Switzerland:''' Possession, production and sale is illegal.<ref>http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html</ref>
*'''China''' - As of October 2015 2C-T-7 is a controlled substance in China.<ref>{{cite web | url=http://www.sfda.gov.cn/WS01/CL0056/130753.html | title=关于印发《非药用类麻醉药品和精神药品列管办法》的通知 | publisher=China Food and Drug Administration | date=27 September 2015 | language=Chinese | accessdate=1 October 2015}}</ref>
*'''United Kingdom''' - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref>
*'''United States''' - On September 20, 2002, 2C-T-7 was classified as a Schedule I substance in the United States by an emergency ruling by the DEA. On March 18, 2004, the DEA published a final rule in the Federal Register which permanently placed 2C-T-7 in Schedule I.{{citation needed}}


==See also==
==See also==

Revision as of 01:37, 10 July 2017

Serious injury or death may occur if 2C-T-7 is insufflated or combined with certain substances and medications (e.g. MAOIs or RIMAs)[1][2][3]

It is strongly discouraged to insufflate (snort), eyeball, administer non-orally, or combine this substance with certain other substances. Please see this section for more details.

Summary sheet: 2C-T-7

Template:SubstanceBox/2-C-T7

2,5-Dimethoxy-4-propylthiophenethylamine (also known as 2C-T-7, Blue Mystic and 7th Heaven, among others) is a synthetic psychedelic substance of the phenethylamine chemical class that produces psychedelic and entactogenic effects when administered. It is a member of the 2C-x family of psychedelic phenethylamines, all of which are derivatives of mescaline.

2C-T-7 was first synthesized by Alexander Shulgin and documented in his book PiHKAL ("Phenethylamines I Have Known and Loved").[4]

It is considered by the community as a highly unpredictable dose sensitive psychedelic that has gained a reputation for its strong, potentially blinding visuals and intense body load that can manifest as fever-like delirium in extreme cases. Many reports indicate that the physical effects are too severe for those who are not already experienced with psychedelics or who have pre-existing medical conditions.

This particular substance is part of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine compounds, all of which -- with the exception of mescaline -- he developed, synthesized and tested on himself. They can be found within the first book of PiHKAL, and are as follows: Mescaline, DOM, 2C-B, 2C-E, 2C-T-2 and 2C-T-7.[5]

Chemistry

Generic structure of a phenethylamine molecule

2C-T-7, or 2,5-dimethoxy-4-propylthiophenethylamine, is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain.

2C-T-7 belongs to the 2C family of phenethylamines, which contain methoxy functional groups CH3O- attached to carbons R2 and R5 of the benzene ring. 2C-T-7 is also substituted at R4 with a propyl thioether group.

2C-T-7 is analogous to 2C-T-2; the two differ by the length of the alkane chain in their thioether functional group.[6]

Pharmacology

Further information: Serotonergic psychedelic

2C-T-7's psychedelic effects have been shown to come from its efficacy at the 5-HT2A receptor as a partial agonist.[7] However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

As the 2,5-desmethoxy derivative of 2C-T-7 has been shown to be a moderate monoamine oxidase An inhibitor, this substance is widely thought to have MAOI effects.

Subjective effects

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Visual effects

Cognitive effects

Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

Toxicity and harm potential

There have been at least three reported deaths related to 2C-T-7 use as of August 2007, mainly at insufflated doses of 30 mg or more[citation needed] or combined with stimulants such as MDMA,[citation needed] as well as a number of very uncomfortably intense effects and hospitalizations due to the insufflation of 2C-T-7.[8]

It is strongly discouraged to administer 2C-T-7 non-orally because this can cause vomiting, numerous negative side effects, or death at high doses. In Erowid's Fall 2000 2C-T-7 survey, it was reported that the insufflation of 2C-T-7 resulted in more negative side effects than oral administration.[citation needed]

It is strongly recommended that one use harm reduction practices, such as volumetric dosing, when using this substance to ensure the accurate administration of the intended dose.

Tolerance and addiction potential

2C-T-7 is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of 2C-T-7 are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 2C-T-7 presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 2C-T-7 all psychedelics will have a reduced effect.

Dangerous interactions

If 2C-T-7 does have MAOI effects as commonly speculated, this could indicate that 2C-T-7 is more likely to induce serotonin syndrome or general neurotransmitter overload (especially at high dosages) than other serotonergic psychedelics.[9] This may make it dangerous to combine it with other MAOIs, stimulants and certain substances which releases neurotransmitters such as serotonin or dopamine. These substances include but are not limited to:

Legality

  • Australia - In Australia, 2C-T-2 and 2C-T-7 are covered by the country's analog drug laws.[citation needed]
  • Brazil - Possession, production and sale is illegal as it is listed on Portaria SVS/MS nº 344.[10]
  • Canada: 2C-T-7 is considered Schedule III as it is a derivative of 2,5-dimethoxyphenethylamine.[11]
  • China - As of October 2015 2C-T-7 is a controlled substance in China.[12]
  • Germany - 2C-T-7 is scheduled in Germany.[citation needed]
  • Latvia - 2C-T-7 is a Schedule I controlled substance in Latvia.[13]
  • Netherlands - The Netherlands was the first country in the world to ban 2C-T-7 after being sold in smart shops for a short period. After 2C-T-2 was first banned, 2C-T-7 quickly appeared on the market but was soon banned as well. 2C-T-7 is a list I drug of the Opium Law.[citation needed]
  • Sweden - The drug is Schedule I in Sweden.[14] 2C-T-7 was first classified as a health hazard under the act "Lagen om förbud mot vissa hälsofarliga varor" (translated as "the Act on the Prohibition of Certain Goods Dangerous to Health") that made it illegal to sell or possess as of April 1, 1999.[citation needed]
  • Switzerland: Possession, production and sale is illegal.[15]
  • United Kingdom - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.[16]
  • United States - On September 20, 2002, 2C-T-7 was classified as a Schedule I substance in the United States by an emergency ruling by the DEA. On March 18, 2004, the DEA published a final rule in the Federal Register which permanently placed 2C-T-7 in Schedule I.[citation needed]

See also

References

  1. "Third Confirmed 2C-T-7 Death". Erowid. April 10, 2001. 
  2. "A Reported 2C-T-7 Death". Erowid. July 2003. 
  3. "Second Reported 2C-T-7 Death". Erowid. April 2, 2001. 
  4. https://erowid.org/library/books_online/pihkal/pihkal.shtml | PiHKAL
  5. https://erowid.org/library/books_online/pihkal/pihkal.shtml | PiHKAL
  6. http://isomerdesign.com/PiHKAL/read.php?id=43
  7. Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats | http://link.springer.com/article/10.1007%2Fs00213-005-0009-4
  8. 2C-T-7 Overdoses & Delirium | https://www.erowid.org/chemicals/2ct7/2ct7_effects.shtml#overdose
  9. Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors:  Biological Activities, CoMFA Analysis, and Active Site Modeling | http://pubs.acs.org/doi/abs/10.1021/jm0493109
  10. http://portal.anvisa.gov.br/documents/10181/3115436/%281%29RDC_130_2016_.pdf/fc7ea407-3ff5-4fc1-bcfe-2f37504d28b7
  11. Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28
  12. "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015. 
  13. Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086
  14. http://www.lakemedelsverket.se/upload/lvfs/LVFS_2004-3.pdf
  15. http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html
  16. Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted