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{{SubstanceBox/DPT}}
{{SubstanceBox/DPT}}


'''N,N-Dipropyltryptamine''' (also known as, '''Dipropyltryptamine''' '''DPT''',  or '''"the Light"''') is a synthetic [[psychoactive class::psychedelic]] of the [[chemical class::tryptamine]] chemical class that produces powerful, short-lived visionary [[psychedelic]] effects similar to, but often considered to be more "challenging" or overwhelming than those of [[DMT]], when [[Routes of administration|administered]]. It is a structural homolog of [[DMT]] that is known to be uniquely similar in its hallucinogenic intensity, albeit with a moderately longer duration, and a greater reported tendency to feel "sinister", "unsettling", and "dysphoric."
'''N,N-Dipropyltryptamine''' (also known as, '''Dipropyltryptamine''' '''DPT''',  or '''"the Light"''') is a synthetic [[psychoactive class::psychedelic]] of the [[chemical class::tryptamine]] chemical class that produces powerful, short-lived visionary [[psychedelic]] effects similar to, but often considered to be more "challenging" or overwhelming than those of [[DMT]], when [[Routes of administration|administered]]. It is a structural homolog of [[DMT]] that is often reported to be uniquely similar in its hallucinogenic intensity, albeit with a moderately longer duration, and a tendency to feel "sinister", "unsettling", and "artificial" relative to DMT and other psychedelic [[tryptamines]].


DPT was first reported in 1973, where it was researched in low doses as an adjunct to therapy for alcoholism.<ref>International Pharmacopsychiatry. 1973;8(1):104.</ref> It has also been researched in high doses to induce peak experiences for terminal cancer patients.<ref>“The Peak Experience Variable in DPT-Assisted Psychotherapy with Cancer Patients”
DPT was first reported in 1973, where it was researched in low doses as an adjunct to therapy for alcoholism.<ref>International Pharmacopsychiatry. 1973;8(1):104.</ref> It has also been researched in high doses to induce peak experiences for terminal cancer patients.<ref>“The Peak Experience Variable in DPT-Assisted Psychotherapy with Cancer Patients”

Revision as of 06:28, 30 May 2017

Summary sheet: DPT
DPT
Chemical Nomenclature
Common names DPT, Dipropyltryptamine, The Light
Substitutive name N,N-Dipropyltryptamine
Systematic name 3-[2-(Dipropylamino)ethyl]indole
Class Membership
Psychoactive class Psychedelic
Chemical class Tryptamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.


Smoked
Dosage
Threshold 10 mg
Light 15 - 20 mg
Common 20 - 50 mg
Strong 50 - 100 mg
Heavy 100 mg +
Duration
Total 30 - 90 minutes
Onset 0 - 1 minutes
After effects 2 - 4 hours
Oral
Dosage
Threshold 50 mg
Light 75 - 150 mg
Common 150 - 250 mg
Strong 250 - 350 mg
Heavy 350 mg +
Duration
Total 2 - 4 hours
Onset 20 - 60 minutes
After effects 2 - 3 hours



Insufflated
Dosage
Threshold 5 mg
Light 20 - 50 mg
Common 50 - 100 mg
Strong 100 - 200 mg
Heavy 200 mg +
Duration
Total 3 - 5 hours
Onset 5 - 20 minutes
Peak 30 - 45 minutes
After effects 2 - 4 hours






DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions


N,N-Dipropyltryptamine (also known as, Dipropyltryptamine DPT, or "the Light") is a synthetic psychedelic of the tryptamine chemical class that produces powerful, short-lived visionary psychedelic effects similar to, but often considered to be more "challenging" or overwhelming than those of DMT, when administered. It is a structural homolog of DMT that is often reported to be uniquely similar in its hallucinogenic intensity, albeit with a moderately longer duration, and a tendency to feel "sinister", "unsettling", and "artificial" relative to DMT and other psychedelic tryptamines.

DPT was first reported in 1973, where it was researched in low doses as an adjunct to therapy for alcoholism.[1] It has also been researched in high doses to induce peak experiences for terminal cancer patients.[2] It has gained some notoriety for its adoption as the primary sacrament for the "Temple of the True Inner Light" in the United States, a Christian off-shoot organization who believe in psychedelic use and refer to it as "the true flesh of God."[3]

DPT is commonly consumed via insufflation or orally. Many report the experience of insufflation to be very painful which, with the rapidness of onset, does not give the user much time to acclimate themselves to its powerful effects. It can also be administered intramuscularly or via vaporization after conversion to the oily freebase, and this appears to be the preferred route of administration in research settings. Smoking DPT freebase is reported to be the preferred route used by the Temple of True Inner Light.

Very little data exists about the pharmacological properties, metabolism, and toxicity of DPT, and it has relatively little history of human usage. It has long been available on the research chemicals market as a legal, grey-market alternative to DMT, and commercially distributed through online vendors. Due to the mentally jarring and disturbing hallucinatory states it can produce, many reports also suggest that this substance may be overly difficult to use safely for those who are not already very experienced with hallucinogens. Therefore it is highly advised to approach this unusually powerful psychedelic substance with the proper amount of precaution and harm reduction practices if choosing to use it.

History and culture

This History and culture section is a stub.

As a result, it may contain incomplete or wrong information. You can help by expanding it.

Chemistry

DPT, or N,N-dipropyltryptamine, is a synthetic indole molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. DPT contains two propyl groups carbon chains bound to the terminal amine RN of its tryptamine backbone.

DPT has a number of substituted analogs such as 4-HO-DPT or 4-AcO-DPT.

Pharmacology

Further information: Serotonergic psychedelic

DPT's psychedelic effects are believed to come from its efficacy at the 5-HT2A and 5-HT1A receptor as a partial agonist.[4]

The role of these interactions and how they result in the psychedelic experience continues to remain subject to ongoing scientific inquiry.

Subjective effects

This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

At light to moderate doses, users often report a slight sense of anaesthetization and relaxation. As the dose increases, hyper-awareness of one's heart rate and breathing increases and body tremors and loss of muscle control are often reported. The effects of DPT can range from strong euphoria and sensuality to nausea, panic, and intense states dysphoria even within the same experience.

Cognitive effects

Visual effects

Enhancements

Distortions

The visual geometry of DPT can be described through its variations as intricate in complexity, both abstract and concrete in form, more digital than organic in feel, choppy and only loosely structured in organization, brightly lit, multicolored in scheme, sharp in its edges, fast in speed, simultaneously smooth and glitching in motion, immersive in depth, and consistent in intensity. At higher doses, it is more likely to result in states of level 8A visual geometry over level 8B.

Hallucinatory states

DPT produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of any other commonly used psychedelic. These effects include:

It should be noted that these effects are the rarest and least reproducible those that can occur during a psychedelic experience. They are considered unique in that that simply taking more of the substance does not necessarily increase the chance they will occur, and are said to rely more on contextual factors such as the user's set and setting rather than the substance or dose itself. Their fullest manifestations are sometimes called "peak", "transcendent" or "transformative" experiences; however, they can still occur on a conceptual or cognitive level that can leave a lasting positive impact on the user.

Experience reports

Anecdotal reports which describe the effects of this compound within our experience index include:

Additional experience reports can be found here:

Toxicity and harm potential

The toxicity and long-term health effects of recreational DPT do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because DPT is a research chemical with very little history of human usage. Anecdotal evidence from people within the community who have tried DPT suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this substance.

Tolerance and addiction potential

DPT is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of DPT are not built.[5]

Legality

This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

  • Latvia: DPT is a Schedule I drug.[6]
  • New Zealand: DPT is an analogue of DMT, so is a Class C controlled drug in New Zealand.[7]
  • Sweden - Following its sale as a designer drug, DPT was made illegal in Sweden on 26 January 2016.[8]
  • United Kingdom: DPT is a Class A drug in the United Kingdom as a result of the tryptamine catch-all clause.[9]
  • United States: DPT is unscheduled in the United States. It may be considered an analogue of DET, a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or industrial intents and purposes could be prosecuted as crimes under the Federal Analogue Act.[citation needed] DPT is a Schedule I controlled substance in the states of Florida, Maine, and Oklahoma making it illegal to buy, sell, or possess.[10] [11]

See also

References

  1. International Pharmacopsychiatry. 1973;8(1):104.
  2. “The Peak Experience Variable in DPT-Assisted Psychotherapy with Cancer Patients” Journal of Psychedelic Drugs. 1977;9(1):1–10.
  3. Temple of the True Inner Light | http://psychede.tripod.com/
  4. William E. Fantegrossi, Chad J. Reissig, Elyse B. Katz, Haley L. Yarosh, Kenner C. Rice, Jerrold C. Winterb. Hallucinogen-like effects of N,N-dipropyltryptamine (DPT): possible mediation by serotonin 5-HT1A and 5-HT2A receptors in rodents. Pharmacol Biochem Behav. 2008 January; 88(3): 358–365.
  5. Tolerance and cross-tolerance to head twitch behavior elicited by phenethylamine- and tryptamine-derived hallucinogens in mice. | https://www.ncbi.nlm.nih.gov/pubmed/25271256
  6. Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (Triptamīni) | http://likumi.lv/doc.php?id=121086
  7. http://www.legislation.govt.nz/act/public/1975/0116/latest/whole.html#DLM436576
  8. (in Swedish) Folkhälsomyndigheten. | https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2016/januari/31-nya-substanser-klassas-som-narkotika-eller-halsofarlig-vara/
  9. Misuse of Drugs Act 1971 (Legislation.gov.uk) |http://www.legislation.gov.uk/ukpga/1971/38/schedule/2/part/I#reference-M_F_c7632653-ddad-4420-f307-e3da1e36d30e
  10. http://leg.state.fl.us/statutes/index.cfm?App_mode=Display_Statute&URL=0800-0899/0893/0893.html | Florida Statutes - Chapter 893 - DRUG ABUSE PREVENTION AND CONTROL
  11. http://www.oscn.net/applications/oscn/DeliverDocument.asp?CiteID=98866