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==Pharmacology==
==Pharmacology==
{{Main|Serotonergic psychedelic}}
{{Further|Serotonergic psychedelic}}
4-AcO-DiPT likely acts as a [[Serotonin#The_5-HT_system|5-HT<sub>2A</sub>]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from 4-AcO-DiPT's efficacy at the 5-HT<sub>2A</sub> receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.
4-AcO-DiPT likely acts as a [[Serotonin#The_5-HT_system|5-HT<sub>2A</sub>]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from 4-AcO-DiPT's efficacy at the 5-HT<sub>2A</sub> receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.


Revision as of 08:29, 5 March 2017

4-AcO-DiPT
Chemical Nomenclature
Common names 4-AcO-DiPT, 4-Acetoxy-DiPT, Ipracetin, Aces
Substitutive name 4-Acetoxy-N,N-diisopropyltryptamine
Systematic name 3-[2-(Diisopropylamino)ethyl]-1H-indol-4-yl acetate
Class Membership
Psychoactive class Psychedelic
Chemical class Tryptamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



⇣ Oral
Dosage
Threshold 3 mg
Light 5 - 15 mg
Common 15 - 30 mg
Strong 30 - 45 mg
Heavy 45 mg +
Duration
Total 3 - 4 hours
Onset 15 - 40 minutes
Come up 20 - 40 minutes
Peak 1.5 - 2 hours
Offset 1 - 1.5 hours
After effects 2 - 6 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions
Summary sheet: 4-AcO-DiPT

4-acetoxy-N,N-diisopropyltryptamine (abbreviated 4-AcO-DiPT; also known as 4-Acetoxy-DiPT and Ipracetin) is a synthetic psychedelic tryptamine.

It is described online as being similar to psilocin combined with 2C-B and has a uniquely short duration of 2 - 4 hours. It is around as potent as 4-HO-DiPT with an active dose reported at between 15 and 40 mg.[1]

Chemistry

4-AcO-DiPT, or 4-acetoxy-N,N-diisopropyltryptamine, is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-AcO-DiPT is substituted at R4 of its indole heterocycle with an acetoxy (AcO) functional group CH3COO−. It also contains two (di) isopropyl chains bound to the terminal amine RN of its tryptamine backbone (DiPT).

4-AcO-DiPT is the N-substituted isopropyl homologue of 4-HO-DMT (Psilocin). 4-AcO-DiPT is the acetate ester analogue of DiPT and the N-substituted diisopropyl analogue of 4-AcO-DMT.[2]

Pharmacology

Further information: Serotonergic psychedelic

4-AcO-DiPT likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from 4-AcO-DiPT's efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

It is worth noting that 4-AcO-DiPT is reported to feel identical to its 4-HO-DiPT counterpart.[1] This is in the same manner that 4-AcO-DMT/4-HO-DMT, 4-AcO-MET/4-HO-MET, and 4-AcO-DET/4-HO-DMT all feel subjectively identical to their counterpart, suggesting that 4-AcO compounds are deacetylated into 4-HO compounds.

Subjective effects

 This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Cognitive effects

Visual effects

Enhancements

Distortions

Geometry

Hallucinatory states

Auditory effects

Toxicity and harm potential

Main articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational 4-AcO-DiPT use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 4-AcO-DiPT is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 4-AcO-DiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

4-AcO-DiPT is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of 4-AcO-DiPT are built almost immediately after ingestion. Afterwards, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 4-AcO-DiPT presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 4-AcO-DiPT all psychedelics will have a reduced effect.

  • United Kingdom - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.[3]
  • Denmark - 4-AcO-DiPT is a Schedule B controlled substance in Denmark.[4]
  • Japan - 4-Acetoxy-DiPT is a controlled substance in Japan.[5]
  • Sweden - 4-AcO-DiPT is illegal to sell or possess in Sweden.[6]
  • United States - 4-Acetoxy-DiPT is an unscheduled substance in the United States. Due to similarities to other scheduled tryptamines such as psilocin and 5-MeO-DiPT, possession may be prosecuted under the Federal Analog Act in the United States.

See also

References

  1. ↑ 1.0 1.1 4-acetoxy-DiPT Primer (Erowid) | https://www.erowid.org/chemicals/4_acetoxy_dipt/4_acetoxy_dipt_primer.shtml
  2. ↑ 4-Acetoxy-DiPT - PubChem | https://pubchem.ncbi.nlm.nih.gov/compound/24801868
  3. ↑ Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted
  4. ↑ https://www.retsinformation.dk/Forms/R0710.aspx?id=137169
  5. ↑ ホーム > 政策について > 分野別の政策一覧 > 健康・医療 > 医薬品・医療機器 > 薬物乱用防止に関する情報 | http://www.mhlw.go.jp/bunya/iyakuhin/yakubuturanyou/scheduled-drug/list.html
  6. ↑ Svensk författningssamling | http://www.notisum.se/rnp/sls/sfs/20050026.pdf
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