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Template:SubstanceBox/Buprenorphine: Difference between revisions

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>Unity
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>Kenan
m Text replacement - "'''WARNING:''' Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. <u>See responsible use section.</u><br> '''DISCLAIMER:''' PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy." to ""
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     |InsufflatedROA_Bioavailability=48%
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     |SublingualROA_Caption='''WARNING:''' Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. <u>[[responsible drug use|See responsible use section]].</u><br> '''[[Disclaimer|DISCLAIMER]]:''' PW's [[dosage]] information is gathered from users and [[Network|resources]] for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
     |SublingualROA_Caption=
     |SublingualROA_Bioavailability= 30%
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     |SublingualROA_Threshold=<0.3 mg
     |SublingualROA_Threshold=<0.3 mg

Revision as of 04:32, 25 January 2017

SubstanceBox/Buprenorphine
Chemical Nomenclature
Common names Buprenex, Subutex, Butrans, Cizdol
Systematic name (2S)-2-[(5R,6R,7R,14S)-9α-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3,3-dimethylbutan-2-ol
Class Membership
Psychoactive class Opioid
Chemical class Morphinan
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.





Sublingual
Dosage
Bioavailability 30%
Threshold <0.3 mg
Light 0.3 - 0.6 mg
Common 0.6 - 1.3 mg
Strong 1.3 - 2.4 mg
Heavy 2.4 mg +
Duration
Total 10 - 18 hours
Onset 40 - 80 minutes
Peak 4 - 8 hours
After effects 1 - 3 days
Insufflated
Dosage
Bioavailability 48%
Threshold < 0.2 mg
Light 0.2 - 0.4 mg
Common 0.4 - 0.8 mg
Strong 0.8 - 1.5 mg
Heavy 1.5 mg +
Duration
Total 8 - 14 hours
Onset 30 - 60 minutes
Peak 4 - 8 hours
After effects 1 - 3 days






DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.