4-AcO-MiPT

4-AcO-MiPT
Chemical Nomenclature
Common names	4-AcO-MiPT, Mipracetin, O-Acetylmiprocin
Substitutive name	4-Acetoxy-N-isopropyl-N-methyltryptamine
Systematic name	[3-[2-[Isopropyl(methyl)amino]ethyl]-1H-indol-4-yl] acetate
Class Membership
Psychoactive class	Psychedelic
Chemical class	Tryptamine
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Threshold 5 mg Light 10 - 15 mg Common 15 - 20 mg Strong 20 - 35 mg Heavy 35 mg + Duration Total 4 - 8 hours Onset 20 - 60 minutes Come up 1 - 2 hours Peak 1.5 - 3 hours Offset 1 - 2 hours After effects 2 - 4 hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Interactions

Summary sheet: 4-AcO-MiPT

4-AcO-MiPT (also known as 4-Acetoxy-N-methyl-N-isopropyltryptamine or Mipracetin) is a synthetically produced psychedelic substance of the tryptamine class. It is the acetylated form of 4-HO-MiPT (also known as Miprocin) and is a higher homolog of 4-AcO-DMT, 4-AcO-MET and 4-AcO-DET. Like the aforementioned compounds, it is commonly hypothesized to act principally as a prodrug for their respective hydroxylated counterparts (e.g. 4-HO-DMT, 4-HO-MET and 4-HO-DET), although there is on-going debate as to whether they possess their own intrinsic activity.

There is very little information on the human pharmacology or toxicity of 4-AcO-MiPT, although analytical methods have been developed for its detection. Today it is either used recreationally or as an entheogenic compound and is typically acquired through the use of online research chemical vendors. It remains relatively uncommon and has very little history of human usage.

Chemistry

4-AcO-MiPT, or 4-Acetoxy-N-isopropyl-N-methyltryptamine, is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R₃ to an amino group via an ethyl side chain. 4-AcO-MiPT is substituted at R₄ of its indole heterocycle with an acetoxy (AcO) functional group CH₃COO−. It also contains isopropyl and methyl chains bound to the terminal amine R_N of its tryptamine backbone (MiPT).

4-AcO-MiPT is the N-substituted methisopropyl homologue of 4-HO-DMT (Psilocin). 4-AcO-MiPT is the acetate ester analog of DMT and the N-substituted methisopropyl analogue of 4-AcO-DMT.

Pharmacology

Main article: Serotonergic psychedelic

Like with most psychedelic tryptamines, 4-AcO-MiPT is thought to act principally as a 5-HT_2A partial agonist. The psychedelic effects are believed to come from 4-AcO-MiPT's binding efficacy at the 5-HT_2A receptors.

However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective effects

This subjective effects section is a stub. As such, it is still in progress and may contain incomplete or wrong information. You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

• Spontaneous tactile sensations
• Increased heart rate
• Nausea
• Pupil dilation

Cognitive effects

• Conceptual thinking
• Cognitive euphoria
• Delusions
• Emotion enhancement
• Immersion enhancement
• Increased music appreciation
• Memory suppression
  • Ego death
• Novelty enhancement
• Personal bias suppression
• Thought loops
• Time distortion
• Unity and interconnectedness

Visual effects

Enhancements

• Colour enhancement
• Pattern recognition enhancement
• Visual acuity enhancement

Distortions

• Drifting (melting, breathing, morphing and flowing)
• Colour shifting
• Depth perception distortions
• Perspective distortions
• Symmetrical texture repetition
• Tracers
• After images
• Brightness alteration
• Diffraction

Geometry

Hallucinatory states

• Transformations
• Internal hallucinations (autonomous entities; settings, sceneries, and landscapes; alterations in perspective and scenarios and plots)

Auditory effects

• Enhancements
• Distortions
• Hallucinations

Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

• Erowid Experience Vaults: 4-AcO-MiPT

Toxicity and harm potential

Main articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational 4-AcO-MiPT use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 4-AcO-MiPT is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 4-AcO-MiPT suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

4-AcO-MiPT is not habit-forming and the desire to use it can actually decrease with regular consumption. Like with most psychedelics it is most often thought to be self-regulating.

Tolerance to the effects of 4-AcO-MiPT are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 4-AcO-MiPT presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 4-AcO-MiPT all psychedelics will have a reduced effect.

Legal issues

This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it.

Due to its relative obscurity, the possession and sale of 4-AcO-MiPT is unscheduled in most countries.

• United Kingdom - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.
• Sweden - Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-AcO-MiPT as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-acetoxi-N,N-metylisopropyltryptamin (4-AcO-MIPT), making it illegal to sell or possess.

See also

• Responsible use
• Research chemical
• 4-AcO-DMT
• 4-AcO-MET
• Tryptamine

External links

• 4-AcO-MiPT (Wikipedia)
• 4-AcO-MiPT (Erowid)
• 4-AcO-MiPT (Bluelight)
• 4-AcO-MiPT (TripSit)