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25x-NBOMe: Difference between revisions

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{{Template:Warning/25x-NBOMe}}
{{GenericPanel/warning
| title=Many drugs in the [[NBOMe|NBOMe series]] have been fatal at heavy doses.<ref name="one">25I-NBOMe (2C-I-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2ci_nbome/2ci_nbome_death.shtml</ref><ref name="two">25C-NBOMe (2C-C-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2cc_nbome/2cc_nbome_death.shtml</ref><ref name="three">Other or Unknown NBOMe Compound Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/nbome/nbome_death.shtml</ref>
| content=It is strongly discouraged to take large amounts of this substance or to [[Routes of administration#Insufflation|insufflate]] (snort) it. Please see [[25x-NBOMe#Toxicity and harm potential|this section]] for more details.
}}
'''25x-NBOMe''' is the general form of the NBOMe series of psychedelic [[phenethylamines]]. The series has nearly no history of human use prior to 2010 when some of the first compounds became available for purchase from online [[research chemical]] vendors.  
'''25x-NBOMe''' is the general form of the NBOMe series of psychedelic [[phenethylamines]]. The series has nearly no history of human use prior to 2010 when some of the first compounds became available for purchase from online [[research chemical]] vendors.  



Revision as of 21:04, 31 May 2016

Many drugs in the NBOMe series have been fatal at heavy doses.[1][2][3]

It is strongly discouraged to take large amounts of this substance or to insufflate (snort) it. Please see this section for more details.

25x-NBOMe is the general form of the NBOMe series of psychedelic phenethylamines. The series has nearly no history of human use prior to 2010 when some of the first compounds became available for purchase from online research chemical vendors.

It is often sold as LSD, but one key difference between 25x-NBOMe and LSD is that NBOMe is only active when taken through a sublingual or insufflated route. This means that in order to get the full effects, 25x-NBOMe blotter paper must be lightly chewed on for 20+ minutes and never immediately swallowed. Insufflation, however, is not recommended; reports of people suffering dangerous and often fatal overdoses due to this route of administration have been surfacing.

Chemistry

In a comparison of 25x-NBOMe and 2C-x chemicals, each 25x-NBOMe molecule is a serotonergic N-benzyl derivative of the corresponding 2C-x molecule. This change in structure results in an increase in potency. It differs from the corresponding 2C-x structurally through a substitution on the amine (NH2) with a 2-methoxybenzyl (BOMe) group. The addition of this BOMe group also causes most of the compounds to have relatively the same duration, regardless of how long the 2C-x counterpart lasts.

Examples

References

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  1. 25I-NBOMe (2C-I-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2ci_nbome/2ci_nbome_death.shtml
  2. 25C-NBOMe (2C-C-NBOMe) Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/2cc_nbome/2cc_nbome_death.shtml
  3. Other or Unknown NBOMe Compound Fatalities / Deaths by Erowid | https://www.erowid.org/chemicals/nbome/nbome_death.shtml