Zolpidem: Difference between revisions
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==Pharmacology== | ==Pharmacology== | ||
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Zolpidem binds to GABA<sub>A</sub> receptor sites (close to benzodiazepine site) and facilitates chloride channel opening. | Zolpidem binds to GABA<sub>A</sub> receptor sites (close to benzodiazepine site) and facilitates chloride channel opening. | ||
==Subjective effects== | ==Subjective effects== | ||
The effects listed below are based upon the [[subjective effects index]] and personal experiences of [[PsychonautWiki]] [[Special:TopUsers|contributors]]. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects. | The effects listed below are based upon the [[subjective effects index]] and personal experiences of [[PsychonautWiki]] [[Special:TopUsers|contributors]]. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects. | ||
Revision as of 18:23, 20 March 2016
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Template:SubstanceBox/zolpidemZolpidem (Brand names Ambien, Intermezzo, Edluar, and Zolpimist[1]) is a non-benzodiazepine hypnotic used in the treatment of insomnia. [1][2] It is an imidazopyridine agonist of the GABAA receptor.[3]
Chemistry
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This chemistry section is incomplete. You can help by adding to it. |
Pharmacology
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This pharmacology section is incomplete. You can help by adding to it. |
Zolpidem binds to GABAA receptor sites (close to benzodiazepine site) and facilitates chloride channel opening.
Subjective effects
The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.
Physical effects
The physical effects of zolpidem can be broken down into several components.
These are described below and generally include:
- Nausea
- Motor control loss
- Dizziness
- Sedation
- Tactile suppression
- Respiratory depression
- Appetite enhancement
- Muscle relaxation
Cognitive effects
The cognitive effects of zolpidem can be broken down into several components.
It contains cognitive effects which generally include:
- Disinhibition
- Anxiety suppression
- Language suppression
- Information processing suppression
- Thought deceleration
- Amnesia
- Compulsive redosing
Visual effects
The visual effects of zolpidem can be broken down into several components.
- Double vision
- Acuity suppression
- Visual disconnection
- Vaguely defined hallucinations
Auditory effects
Toxicity and harm potential
Lethal dosage
It is strongly recommended that one use harm reduction practices when using this drug.
Tolerance and addiction potential
Legal issues
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This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it. |