Warning
This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.

Phencyclidines: Difference between revisions

From PsychonautWiki Archive
Jump to navigation Jump to search
← Older editNewer edit →
>Oskykins
>Oskykins
Line 18: Line 18:
==Toxicity and Harm Potential==
==Toxicity and Harm Potential==
===Psychosis===
===Psychosis===
Certain phencyclidines, including [[3-MeO-PCP]] and [[PCP]], have been reported to cause [[psychosis]] and mania at a significantly higher rate than other [[dissociatives]] like [[ketamine]], [[diphenidine]], or [[MXE]]. There are a significant amount of reports in the medical literature and throughout online forums which describe states of psychosis, mania, delirium, and/or catatonia after abusing these drugs.<ref name="three">The Big & Dandy 3-MeO-PCP Thread - Part 2 (Bluelight) | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2</ref><ref name="two">The Big & Dandy 3-MeO-PCP Thread - Mad Manic Meo 3nity | http://www.bluelight.org/vb/threads/760934-The-Big-amp-Dandy-3-MeO-PCP-Thread-Mad-Manic-Meo-3nity</ref><ref name="one">The Big & Dandy 3-MeO-PCP Thread - Part 1 (Bluelight) | http://www.bluelight.org/vb/threads/454099-The-Big-amp-Dandy-3-MeO-PCP-Thread-%28Part-1%29</ref> In some cases, it has resulted in hospitalization and occasionally has taken up to a week or more to resolve.<ref>The Big & Dandy 3-MeO-PCP Thread - Part 2 | Page 18 | 10-08-2014 09:10  | Post #448 by Sekio (Administrator) | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2?p=12523821&viewfull=1#post12523821</ref><ref>The Big & Dandy 3-MeO-PCP Thread - Part 2 | Page 20 | 30-08-2014 14:08 | Post #481 by Chocodoobie | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2?p=12559322&viewfull=1#post12559322</ref><ref>The Big & Dandy 3-MeO-PCP Thread - Part 3 | Page 1 |  23-06-2015 11:53 | Post #5 by Confield | http://www.bluelight.org/vb/threads/760934-The-Big-amp-Dandy-3-MeO-PCP-Thread-Mad-Manic-Meo-3nity?p=13108675&viewfull=1#post13108675</ref><ref>https://www.erowid.org/experiences/exp.php?ID=103972 | NumbnDumb. "So Strong I'm Shocked: An Experience with 3-MeO-PCP (ID 103972)". Erowid.org. Jan 24, 2016. erowid.org/exp/103972</ref>
Certain phencyclidines, including [[3-MeO-PCP]] and [[PCP]], have been reported to cause [[psychosis]] and mania at a significantly higher rate than other [[dissociatives]] like [[ketamine]], [[diphenidine]], or [[MXE]]. There are a significant amount of reports in the medical literature and throughout online forums which describe states of psychosis, mania, delirium, and/or catatonia after abusing these drugs.<ref name="three">The Big & Dandy 3-MeO-PCP Thread - Part 2 (Bluelight) | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2</ref><ref name="two">The Big & Dandy 3-MeO-PCP Thread - Mad Manic Meo 3nity | http://www.bluelight.org/vb/threads/760934-The-Big-amp-Dandy-3-MeO-PCP-Thread-Mad-Manic-Meo-3nity</ref><ref name="one">The Big & Dandy 3-MeO-PCP Thread - Part 1 (Bluelight) | http://www.bluelight.org/vb/threads/454099-The-Big-amp-Dandy-3-MeO-PCP-Thread-%28Part-1%29</ref> In one initial human trial of [[PCP]], it was reported that one-sixth of the patients who had received anaesthetic doses became psychotic.<ref name="five">http://archives.drugabuse.gov/pdf/monographs/21.pdf | Luisada, Paul V., M.D. "The Phencyclidine Psychosis: Phenomenology and Treatment." Phencyclidine (PCP) Abuse: An Appraisal. Rockville, Maryland: National Institute on Drug Abuse, 1978. pg. 241.</ref> Similar results (although less severe) were reported during trials using subanesthetic doses of PCP for pain relief.<ref name="four">Tasman, Allan, Jerald Kay, and Jeffrey A. Lieberman. Psychiatry. Chichester: John Wiley & Sons, 2003. Google Books. Wiley. Web. <https://books.google.com/books?id=l2KRBgAAQBAJ&pg=PT4957&lpg=PT4957&dq=Greifenstein+et+al.+1958%29.&source=bl&ots=s5CFdAfMzc&sig=GzsOq_N-V1qtahxyyHnKMJceEj0&hl=en&sa=X&ved=0ahUKEwji0pWTjNLKAhUBaD4KHTfqD0sQ6AEIHDAA#v=onepage&q=Greifenstein%20et%20al.%201958%29.&f=false>.</ref>  
 
In one initial human trial of [[PCP]], it was reported that one-sixth of the patients who had received anaesthetic doses became psychotic.<ref name="one">http://archives.drugabuse.gov/pdf/monographs/21.pdf | Luisada, Paul V., M.D. "The Phencyclidine Psychosis: Phenomenology and Treatment." Phencyclidine (PCP) Abuse: An Appraisal. Rockville, Maryland: National Institute on Drug Abuse, 1978. pg. 241.</ref> In some cases, it took up to a week or more to resolve. Similar results (although less severe) were reported during trials using subanesthetic doses of PCP for pain relief.<ref name="two">Tasman, Allan, Jerald Kay, and Jeffrey A. Lieberman. Psychiatry. Chichester: John Wiley & Sons, 2003. Google Books. Wiley. Web. <https://books.google.com/books?id=l2KRBgAAQBAJ&pg=PT4957&lpg=PT4957&dq=Greifenstein+et+al.+1958%29.&source=bl&ots=s5CFdAfMzc&sig=GzsOq_N-V1qtahxyyHnKMJceEj0&hl=en&sa=X&ved=0ahUKEwji0pWTjNLKAhUBaD4KHTfqD0sQ6AEIHDAA#v=onepage&q=Greifenstein%20et%20al.%201958%29.&f=false>.</ref>
 
 
 
There are numerous reports in the medical literature and throughout online forums, which have identified an increased risk of developing psychotic symptoms when using phencyclidines, arylcyclohexylamines and other NMDA antagonists.
 
This risk appears to be increased when other substances such as psychedelics, stimulants, and deliriants are combined; and when the drug is used habitually over the course of several days.
 
Because of this, it is advised that the use of phencyclidines should be kept to a respectable minimum, and that combinations should only be explored by experienced travellers who have carefully and steadily increased their dose over time, fully understand and are prepared for the risks. As always, a sitter is recommended when exploring any new substance or dosage.
 
Phencyclidines appear to cause trouble more reliably than other NMDA antagonists, likely because of its structural [[piperidine]] ring, and because of their potency and duration.


In some cases, 3-MeO-PCP and PCP use has resulted in hospitalization and has occasionally taken up to a week or more to resolve.<ref name="four"></ref><ref>The Big & Dandy 3-MeO-PCP Thread - Part 2 | Page 18 | 10-08-2014 09:10  | Post #448 by Sekio (Administrator) | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2?p=12523821&viewfull=1#post12523821</ref><ref>The Big & Dandy 3-MeO-PCP Thread - Part 2 | Page 20 | 30-08-2014 14:08 | Post #481 by Chocodoobie | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2?p=12559322&viewfull=1#post12559322</ref><ref>The Big & Dandy 3-MeO-PCP Thread - Part 3 | Page 1 |  23-06-2015 11:53 | Post #5 by Confield | http://www.bluelight.org/vb/threads/760934-The-Big-amp-Dandy-3-MeO-PCP-Thread-Mad-Manic-Meo-3nity?p=13108675&viewfull=1#post13108675</ref><ref>https://www.erowid.org/experiences/exp.php?ID=103972 | NumbnDumb. "So Strong I'm Shocked: An Experience with 3-MeO-PCP (ID 103972)". Erowid.org. Jan 24, 2016. erowid.org/exp/103972</ref>
===References===
===References===
{| class="wikitable mw-collapsible mw-collapsed"
{| class="wikitable mw-collapsible mw-collapsed"

Revision as of 20:35, 1 February 2016

Structure of phencyclidine

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

Phencyclidines refers to a class of compounds which typically produce dissociative anaesthesia.

Chemistry

Pharmacology

Examples

Toxicity and Harm Potential

Psychosis

Certain phencyclidines, including 3-MeO-PCP and PCP, have been reported to cause psychosis and mania at a significantly higher rate than other dissociatives like ketamine, diphenidine, or MXE. There are a significant amount of reports in the medical literature and throughout online forums which describe states of psychosis, mania, delirium, and/or catatonia after abusing these drugs.[1][2][3] In one initial human trial of PCP, it was reported that one-sixth of the patients who had received anaesthetic doses became psychotic.[4] Similar results (although less severe) were reported during trials using subanesthetic doses of PCP for pain relief.[5]

In some cases, 3-MeO-PCP and PCP use has resulted in hospitalization and has occasionally taken up to a week or more to resolve.[5][6][7][8][9]

References

Substance Source Circumstance (total dose / duration) Consequences
PCP Bluelight thread title 1 gram over 3 days Shit got fucked up
etc etc etc etc

See also

References

  1. ↑ The Big & Dandy 3-MeO-PCP Thread - Part 2 (Bluelight) | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2
  2. ↑ The Big & Dandy 3-MeO-PCP Thread - Mad Manic Meo 3nity | http://www.bluelight.org/vb/threads/760934-The-Big-amp-Dandy-3-MeO-PCP-Thread-Mad-Manic-Meo-3nity
  3. ↑ The Big & Dandy 3-MeO-PCP Thread - Part 1 (Bluelight) | http://www.bluelight.org/vb/threads/454099-The-Big-amp-Dandy-3-MeO-PCP-Thread-%28Part-1%29
  4. ↑ http://archives.drugabuse.gov/pdf/monographs/21.pdf | Luisada, Paul V., M.D. "The Phencyclidine Psychosis: Phenomenology and Treatment." Phencyclidine (PCP) Abuse: An Appraisal. Rockville, Maryland: National Institute on Drug Abuse, 1978. pg. 241.
  5. ↑ 5.0 5.1 Tasman, Allan, Jerald Kay, and Jeffrey A. Lieberman. Psychiatry. Chichester: John Wiley & Sons, 2003. Google Books. Wiley. Web. <https://books.google.com/books?id=l2KRBgAAQBAJ&pg=PT4957&lpg=PT4957&dq=Greifenstein+et+al.+1958%29.&source=bl&ots=s5CFdAfMzc&sig=GzsOq_N-V1qtahxyyHnKMJceEj0&hl=en&sa=X&ved=0ahUKEwji0pWTjNLKAhUBaD4KHTfqD0sQ6AEIHDAA#v=onepage&q=Greifenstein%20et%20al.%201958%29.&f=false>.
  6. ↑ The Big & Dandy 3-MeO-PCP Thread - Part 2 | Page 18 | 10-08-2014 09:10 | Post #448 by Sekio (Administrator) | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2?p=12523821&viewfull=1#post12523821
  7. ↑ The Big & Dandy 3-MeO-PCP Thread - Part 2 | Page 20 | 30-08-2014 14:08 | Post #481 by Chocodoobie | http://www.bluelight.org/vb/threads/697059-The-Big-amp-Dandy-3-MeO-PCP-Thread-Part-2?p=12559322&viewfull=1#post12559322
  8. ↑ The Big & Dandy 3-MeO-PCP Thread - Part 3 | Page 1 | 23-06-2015 11:53 | Post #5 by Confield | http://www.bluelight.org/vb/threads/760934-The-Big-amp-Dandy-3-MeO-PCP-Thread-Mad-Manic-Meo-3nity?p=13108675&viewfull=1#post13108675
  9. ↑ https://www.erowid.org/experiences/exp.php?ID=103972 | NumbnDumb. "So Strong I'm Shocked: An Experience with 3-MeO-PCP (ID 103972)". Erowid.org. Jan 24, 2016. erowid.org/exp/103972
Retrieved from "http://psy.st/w/index.php?title=Phencyclidines&oldid=51540"