Dextroamphetamine

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Summary sheet: Dextroamphetamine

Dextroamphetamine
Chemical Nomenclature
Common names	Dextroamphetamine, Dexamphetamine, D-amphetamine,Dexedrine, Dex, Attentin
Substitutive name	D-Amphetamine
Systematic name	(2S)-1-phenylpropan-2-amine
Class Membership
Psychoactive class	Stimulant
Chemical class	Phenethylamine
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Bioavailability 20-25-75%+ Threshold 3.75 mg Light 3.75 - 10 mg Common 10 - 16 mg Strong 16 - 30 mg Heavy 30 mg + Duration Total 6 - 8 hours Onset 15 - 30 minutes Come up 30 - 60 minutes Peak 2.5 - 4 hours Offset 2 - 3 hours After effects 3 - 6 hours ⇣ Insufflated Dosage Threshold 3 mg Light 3 - 7.5 mg Common 7.5 - 12 mg Strong 12 - 21.5 mg Heavy 21.5 mg + Duration Total 3 - 6 hours Onset 1 - 5 minutes Come up 5 - 15 minutes Peak 1 - 2 hours Offset 1.5 - 3 hours After effects 2 - 4 hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Interactions
Alcohol
GHB
GBL
Opioids
Cannabis
Caffeine
Ketamine
Methoxetamine
Psychedelics
Cocaine
DXM
PCP
25x-NBOMe
2C-T-x
5-MeO-xxT
DOx
Tramadol
aMT
MAOIs

Dextroamphetamine (also known as Dexamphetamine, D-Amphetamine, Dex, or by brand names including Adderall, Dexedrine) is a stimulant substance and one of the two optical isomers of amphetamine.

Dextroamphetamine is the more potent isomer of the two, but the effects are also slightly different in character. The small difference in affinity affects the mechanism resulting in a more mentally focused stimulation rather than physical, thus creating a stimulant that is more fit for functionally/therapeutically useful drug rather than a recreational stimulant. Therefore, the dextrorotatory enantiomer is preferred in treatment of attention deficit hyperactivity disorder, whereas a racemic mixture like amphetamine is found when sold on the streets.

It is highly advised to use harm reduction practices if using this substance.

Chemistry

With regular synthesis, the resulting product will always be a racemic mixture. An enantiopure can be obtained through a biological synthesis route, where certain proteins form only one of the two isomers or through isolation of one isomer from a previously racemic mixture. Financially it would be beneficial to use the biological process, since it requires only little materials, but instead can be performed by bacteria that can be genetically altered to perform the synthesis for you. Those bacteria multiply by themselves, thus automatically creating a long-term production solution.

History and culture

In 1935, 3 years after amphetamine became widely marketed, the medical community became aware of the stimulant properties of amphetamine, specifically dextroamphetamine, and in 1937 Smith, Kline, and French introduced tablets under the tradename Dexedrine. Dexedrine is used to treat narcolepsy, attention disorders, and obesity. Additionally, it is used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant.

Legal status

Internationally, amphetamine (and its isomers dextroamphetamine and levoamphetamine) are Schedule II controlled substances under the United Nations 1971 Convention on Psychotropic Substances.

See also

• Responsible use
• Stimulant
• Amphetamine

External links

• Dextroamphetamine (Wikipedia)
• Dextroamphetamine (Erowid Vault)