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'''Theobromine''' ('''3,7-dimethyl-1H-purine-2,6-dione''' or '''xantheose''') is a bitter, white [[Psychoactive class::stimulant]] drug of the [[xanthine]] class that is closely related to [[caffeine]]. It is one of the main metabolites of [[caffeine]] and is the main alkaloid of [[theobroma cacao]] and its preparations: cocoa and chocolate. It is similar to [[caffeine]] in both its chemical structure and effects but weaker in its antagonism of adenosine receptors.
'''Theobromine''' ('''3,7-dimethyl-1H-purine-2,6-dione''' or '''xantheose''') is a bitter, white [[Psychoactive class::stimulant]] drug of the [[xanthine]] class that is closely related to [[caffeine]]. It is one of the main metabolites of [[caffeine]] and is the main alkaloid of [[theobroma cacao]] and its preparations: cocoa and chocolate. It is similar to [[caffeine]] in both its chemical structure and effects but weaker in its antagonism of adenosine receptors.
Theobromine dilates blood vessels and causes a slight increase in cerebral blood flow, but it is not known if this has any effect on cognition. Cocoa Extract, which contains large amounts of Theobromine has been found to increase cerebral oxygenation in young people, but there was no measured increase in cognition<ref>https://pubmed.ncbi.nlm.nih.gov/16794461/</ref>
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Theobromine (3,7-dimethyl-1H-purine-2,6-dione or xantheose) is a bitter, white stimulant drug of the xanthine class that is closely related to caffeine. It is one of the main metabolites of caffeine and is the main alkaloid of theobroma cacao and its preparations: cocoa and chocolate. It is similar to caffeine in both its chemical structure and effects but weaker in its antagonism of adenosine receptors.
Theobromine dilates blood vessels and causes a slight increase in cerebral blood flow, but it is not known if this has any effect on cognition. Cocoa Extract, which contains large amounts of Theobromine has been found to increase cerebral oxygenation in young people, but there was no measured increase in cognition[1]
Theobromine's pharmacology is very similar to the pharmacology of caffeine. Like caffeine, theobromine mainly functions as an adenosine receptor antagonist, and also acts as a non-selective inhibitor of phosphodiesterase (PDE).
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
Physical effects
If applicable, a brief paragraph summary of the substance's physical effects may be included here.
You may select physical effects to add below here.
Stimulation - Theobromine induces stimulation similar to, but weaker than the stimulation induced by caffeine.
If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.
You may select from a list of cognitive effects to add below here.
Anxiety - Theobromine causes decrease in anxiety and increased confidence at lower to moderate doses but can cause this effect at higher doses, causing nervousness and tremors.
There are currently no anecdotal reports which describe the effects of this compound within our experience index.
Toxicity and harm potential
This toxicity and harm potential section is a stub.
As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.
Warning:Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).
Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.
