Warning
This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.

HXE: Difference between revisions

From PsychonautWiki Archive
Jump to navigation Jump to search
>Psychonaut007
Added more information about HXE
>Psychonaut007
m Changes MXiPr for HXE
Line 101: Line 101:
{{toxicity}}
{{toxicity}}


The toxicity and long-term health effects of recreational MXiPr use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because MXiPr has very little history of human usage.
The toxicity and long-term health effects of recreational HXE use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because MXiPr has very little history of human usage.


It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.

Revision as of 19:51, 14 April 2021


This page has not been fully approved by the PsychonautWiki administrators.

It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.

Summary sheet: HXE
HXE
Chemical Nomenclature
Common names DMT, Dimethyltryptamine, Dmitri
Substitutive name N,N-Dimethyltryptamine
Systematic name 2-(1H-Indol-3-yl)-N,N-dimethylethanamine
Class Membership
Psychoactive class Psychedelic
Chemical class Tryptamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



Oral
Dosage
Bioavailability x"x" is not a number.% - y"y" is not a number.%[1]
Threshold x"x" is not a number. - mg
Light x"x" is not a number. - y"y" is not a number. mg
Common x"x" is not a number. - y"y" is not a number. mg
Strong x"x" is not a number. - y"y" is not a number. mg
Heavy x"x" is not a number. mg +
Duration
Total x"x" is not a number. - y"y" is not a number. hours
Onset x"x" is not a number. - y"y" is not a number. minutes
Come up x"x" is not a number. - y"y" is not a number. minutes
Peak x"x" is not a number. - y"y" is not a number. hours
Offset x"x" is not a number. - y"y" is not a number. hours
After effects x"x" is not a number. - y"y" is not a number. hours


Sublingual
Dosage
Bioavailability x"x" is not a number.% - y"y" is not a number.%
Threshold x"x" is not a number. - mg
Light x"x" is not a number. - y"y" is not a number. mg
Common x"x" is not a number. - y"y" is not a number. mg
Strong x"x" is not a number. - y"y" is not a number. mg
Heavy x"x" is not a number. mg +
Duration
Total a"a" is not a number. - b"b" is not a number. hours
Onset a"a" is not a number. - b"b" is not a number. minutes
Come up a"a" is not a number. - b"b" is not a number. minutes
Peak a"a" is not a number. - b"b" is not a number. hours
Offset a"a" is not a number. - b"b" is not a number. hours
After effects a"a" is not a number. - b"b" is not a number. hours







DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions


3-HO-2'-Oxo-PCE (commonly known as HXE) is a dissociative substance of the arylcyclohexylamine class that produces ketamine-like dissociative effects when administered. It is structurally related to MXE, ketamine, and PCE.

Limited data exists about the pharmacological properties, metabolism, and toxicity of HXE in humans, and it has a limited history of human use. It is highly advised to use harm reduction practices if using this substance.

History and culture

HXE first appeared for sale on the online research chemical market in late 2020.

Chemistry

HXE or 2-(Ethylamino)-2-(3-hydroxyphenyl)cyclohexan-1-one is classed as an Arylcyclohexylamine

Pharmacology

Very little is known about the pharmacology about this substance, however as an arylcyclohexamine it is reasonable to assume that it is an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. Dissociatives close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually an almost identical equivalent of the famous “k-hole.”

Subjective effects

This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Visual effects

Cognitive effects

Auditory effects

Multi-sensory effects

Transpersonal effects

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

Toxicity and harm potential

This toxicity and harm potential section is a stub.

As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it.
Note: Always conduct independent research and use harm reduction practices if using this substance.

The toxicity and long-term health effects of recreational HXE use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because MXiPr has very little history of human usage.

It is strongly recommended that one use harm reduction practices when using this substance.

Lethal dosage

Tolerance and addiction potential

Dangerous interactions

This dangerous interactions section is a stub.

As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

See also

{{#l:HXE.svg}}

Literature

  • APA formatted reference

Please see the citation formatting guide if you need assistance properly formatting citations.

References

  1. APA formatted citation.


Please see the citation formatting guide if you need assistance properly formatting citations.

References