Talk:Thebaine

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Summary sheet: Thebaine

Thebaine
Chemical Nomenclature
Common names	DMT, Dimethyltryptamine, Dmitri
Substitutive name	N,N-Dimethyltryptamine
Systematic name	2-(1H-Indol-3-yl)-N,N-dimethylethanamine
Class Membership
Psychoactive class	Psychedelic
Chemical class	Tryptamine
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Bioavailability x% - y% Threshold x - mg Light x - y mg Common x - y mg Strong x - y mg Heavy x mg + Duration Total x - y hours Onset x - y minutes Come up x - y minutes Peak x - y hours Offset x - y hours After effects x - y hours ⇣ Sublingual Dosage Bioavailability x% - y% Threshold x - mg Light x - y mg Common x - y mg Strong x - y mg Heavy x mg + Duration Total a - b hours Onset a - b minutes Come up a - b minutes Peak a - b hours Offset a - b hours After effects a - b hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

History and culture

This History and culture section is a stub. As a result, it may contain incomplete or wrong information. You can help by expanding it.

Chemistry

Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid naturally occurring in opium poppies.

Pharmacology

thebaine is chemically similar to both morphine and codeine, but has stimulatory rather than depressant effects. At high doses, it causes convulsions similar to strychnine poisoning. The synthetic enantiomer (+)-thebaine does show analgesic effects apparently mediated through opioid receptors, unlike the inactive natural enantiomer (−)-thebaine.[3] While thebaine is not used therapeutically, it is the main alkaloid extracted from Papaver bracteatum (Iranian opium / Persian poppy) and can be converted industrially into a variety of compounds, including hydrocodone, hydromorphone, oxycodone, oxymorphone, nalbuphine, naloxone, naltrexone, buprenorphine and etorphine. Butorphanol can also be derived from thebaine.[4]

Subjective effects

This subjective effects section is a stub. As such, it is still in progress and may contain incomplete or wrong information. You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

• • Stimulation
  Thebaine produces moderate stimulation at high doses which can result in an inability to sleep and restlessness, the stimulation caused by thebaine can be described as uncomfortable rather than euphoric.
  • Increased Perspiration
  • Sleeplessness
  Thebaine can cause a user to be unable to sleep due to its stimulant properties.

Visual effects

• If applicable, a brief paragraph summary of the substance's visual effects may be included here. You may select visual effects to add below here.

  Enhancements

  • Visual acuity effect1

  Distortions

  • Visual distortion effect1

  Geometry

  If applicable, a brief paragraph summary describing the visual geometry produced by the substance may be included here.

  Hallucinatory states

  If applicable, a brief summary of the substance's visual effects profile may be written here.

  • Hallucinatory states1

Cognitive effects

• If applicable, a brief paragraph summary of the substance's cognitive effects may be included here. You may select from a list of cognitive effects to add below here.
  • Cognitive effect1
  • Cognitive effect2
  • Cognitive effect3

Auditory effects

• If applicable, a brief paragraph summary of the substance's auditory effects may be included here. You may select from a list of auditory effects to add below here.
  • Auditory effect1
  • Auditory effect2

Multi-sensory effects

• If applicable, a brief paragraph summary of the substance's multisensory effects may be included here. You may select from a list of multisensory effects to add below here.
  • Multisensory effect1
  • Multisensory effect2

Transpersonal effects

• If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here. You may select from a list of transpersonal effects to add below here.
  • Transpersonal effect1
  • Transpersonal effect2

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

• Erowid Experience Vaults: SUBSTANCE

Toxicity and harm potential

Thebaine is very toxic and high doses produce symptoms similar to strychnine poisoning. It is strongly recommended that one use harm reduction practices when using this substance.

Tolerance and addiction potential

Thebaine is considered of low abuse potential due to its toxic effects on the body.

Dangerous interactions

This dangerous interactions section is a stub. As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status

Thebaine is controlled under international law, is listed as a Class A drug under the Misuse of Drugs Act 1971 in the United Kingdom, is controlled as an analog of a Schedule II drug per the Analog Act in the United States, and is controlled with its derivatives and salts, as a Schedule I substance of the Controlled Drugs and Substances Act in Canada.[5] The 2013 US Drug Enforcement Administration (DEA) aggregate manufacturing quota for thebaine (ACSCN 9333) was unchanged from the previous year at 145 metric tons.

See also

• Responsible use

External links

(List along order below)

• SUBSTANCE (Wikipedia)
• SUBSTANCE (Erowid Vault)
• SUBSTANCE ([PiHKAL or TiHKAL] / Isomer Design)

Literature

• APA formatted reference

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