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{{SubstanceBox/Trazodone}}
{{SubstanceBox/Trazodone}}


'''Trazodone''', first sold as '''Oleptro''', is an antidepresant of the [[Serotonin#Antagonists|serotonin antagonist]] and [[reuptake inhibitor]] (SARI) class, approved as a prescription medicine for major depressive disorder in adults. Trazodone has [[mCPP|''meta''-Chlorophenylpiperazine]] or  [[mCPP|"chlorophenylpiperazine"]] as an active metabolite that contributes to trazodone's pharmacology. <ref> 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole | http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1982.tb04701.x/abstract;jsessionid=9006CB66248FC2F30E99D5AEAB847661.f04t01</ref>
'''Trazodone''', first sold as '''Oleptro''', is an antidepresant of the [[Serotonin#Antagonists|serotonin antagonist]] and [[reuptake inhibitor]] (SARI) class, approved as a prescription medicine for major depressive disorder in adults. Trazodone produces [[mCPP|''meta''-Chlorophenylpiperazine]] ([[mCPP|"chlorophenylpiperazine"]]) as an active metabolite; it contributes to trazodone's pharmacology. <ref> 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole | http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1982.tb04701.x/abstract;jsessionid=9006CB66248FC2F30E99D5AEAB847661.f04t01</ref>
[[File:Trazodone (mCPP moiety labelled).svg|300px|thumbnail|right|Trazodone. Notice the [[mCPP]] moiety.]]
[[File:Trazodone (mCPP moiety labelled).svg|300px|thumbnail|right|Trazodone. Notice the [[mCPP]] moiety.]]


Revision as of 19:17, 20 June 2019

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Summary sheet: Trazodone
Trazodone
Chemical Nomenclature
Common names Trazodone
Substitutive name Desyrel, Molipaxin, Oleptro, Trazorel, Trittico
Class Membership
Psychoactive class Sedative, Antidepressant
Chemical class Triazolopyridine, phenylpiperazine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



⇣ Oral
Dosage
Threshold x - x mg
Light x - x mg
Common x - x mg
Strong x - x mg
Heavy x - x mg
Duration
Total x hours
Onset 1 hour









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.


Trazodone, first sold as Oleptro, is an antidepresant of the serotonin antagonist and reuptake inhibitor (SARI) class, approved as a prescription medicine for major depressive disorder in adults. Trazodone produces meta-Chlorophenylpiperazine ("chlorophenylpiperazine") as an active metabolite; it contributes to trazodone's pharmacology. [1]

Trazodone. Notice the mCPP moiety.

Discussion

References

  1. ↑ 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole | http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.1982.tb04701.x/abstract;jsessionid=9006CB66248FC2F30E99D5AEAB847661.f04t01
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