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{{SubstanceBox/2C-P}}
{{SubstanceBox/2C-P}}


'''2,5-Dimethoxy-4-propylphenethylamine''' (commonly known as '''2C-P''') is a synthetic [[Psychoactive class::psychedelic]] of the [[Chemical class::phenethylamine]] chemical class that produces a long-lived, highly dose-sensitive array of [[psychedelic]] effects when [[Routes of administration|administered]]. It is a member of the [[2C-x]] family and was first synthesized and documented by [[Alexander Shulgin]] in his book [[PiHKAL]] ("Phenethylamines I Have Known and Loved")<ref>https://erowid.org/library/books_online/pihkal/pihkal.shtml | [[PiHKAL]] </ref>.
'''2,5-Dimethoxy-4-propylphenethylamine''' (also known as '''2C-P''') is a lesser-known [[Psychoactive class::psychedelic]] of the [[chemical class::phenethylamine]] class. 2C-P is a relatively obscure member of the [[2C-x]] family of psychedelic phenethylamines and is known to be one of the most potent, longest-lived, and dose-sensitive of the series.  


Along with other alkylated [[2C-x]] substances like [[2C-E]], this compound is known particularly for its unusually long duration, powerful, sometimes overwhelming visuals, and intense "body load" (such as persisting [[nausea]], [[muscle tension]] and general bodily discomfort). It is often described by users as a substance which is very similar to that of [[2C-E]] yet distinct in its own effects.  
2C-P was first synthesized and tested for human activity by [[Alexander Shulgin]], who documented his findings in the 1991 book [[PiHKAL]] ("Phenethylamines I Have Known and Loved")<ref>https://erowid.org/library/books_online/pihkal/pihkal.shtml | [[PiHKAL]] </ref>. The reports found in the 2C-P PiHKAL entry remark on its depth and long onset and duration of action, with the commentary section describing 16 mg as a clear overdose with physical consequences. The commentary also notes the small window separating an adequate dose from an excessive dose, suggesting it is relatively easy to overdose on.


Today, 2C-P is either used as a [[recreational drug use | recreational substance]] or an [[entheogen]], rarely sold on the streets and almost exclusively obtained as a grey area [[research chemical]] through online vendors.  
User reports following the publication of PiHKAL tend to characterize 2C-P in terms of its unusually long duration, powerful, sometimes overwhelming visuals, and intense "body load" (such as persisting [[nausea]], [[muscle tension]] and general bodily discomfort). 2C-P's head space and visuals have been described as possessing more similarities to alkylated 2C's like [[2C-E]] than halogenated members like [[2C-B]] or [[2C-I]]. Some reports suggest it may be easier to experience agitation and delirium on 2C-P than other 2C's, perhaps owing to the ease in which it can be mishandled. As a result, it is considered to have a questionable safety profile.


This substance may be overly intense for those who are not already experienced with psychedelics due its often powerful effects and unusually long duration. For this reason, it is strongly recommended that one use [[harm reduction practices]] if choosing to use with this substance.
Due its powerful effects and unusually long duration, 2C-P may be overly intense and difficult to use safely for those who are not already experienced with [[hallucinogens]]. It is strongly advised to use [[harm reduction practices]] if using this substance. Dosing practices like "eye-balling" (i.e. not using a reliable milligram scale) or non-oral routes of administration should especially be avoided.


==Chemistry==
==Chemistry==
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|{{effects/physical|
|{{effects/physical|
*'''[[Effect::Stimulation]]''' - In terms of its effects on the physical energy levels of the user 2C-P is usually considered to be very energetic and stimulating in a fashion that is quite comparable to that of [[2C-B]], [[2C-I]] and other substances within the [[2C-x]] family, being encouraged instead of forced.
*'''[[Effect::Stimulation]]''' - 2C-P is considered to be very energetic and stimulating in a fashion that is comparable to that of [[2C-B]], [[2C-I]] and other substances within the [[2C-x]] family, being encouraged instead of forced.
*'''[[Effect::Spontaneous physical sensations]]''' - In comparison to [[2C-E]] or [[2C-B]], the "body high" of 2C-P can be considered as mild although still capable of becoming very powerful and highly physically euphoric. It is similar yet distinct from the "body high" experienced on [[2C-E]], [[2C-B]], and [[LSD]]. The sensation itself can be described as intense and will manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves. This is coupled by an equally intense yet slightly uncomfortable energetic pins and needles sensation that constantly encompasses a person’s entire body as well as a slight warm glow that manifests itself much less consistently than the other two physical components. All of these are capable of becoming very physically euphoric.  
*'''[[Effect::Spontaneous bodily sensations]]''' - In comparison to [[2C-E]] or [[2C-B]], the "body high" of 2C-P can be considered as mild although still capable of becoming very powerful and highly physically euphoric. It is similar yet distinct from the "body high" experienced on [[2C-E]], [[2C-B]], and [[LSD]]. The sensation itself can be described as intense and will manifest itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves. This is coupled by an equally intense yet slightly uncomfortable energetic pins and needles sensation that constantly encompasses a person’s entire body as well as a slight warm glow that manifests itself much less consistently than the other two physical components. All of these are capable of becoming very physically euphoric.  
*'''[[Effect::Tactile enhancement]]''' - This particular component is particularly prominent but capable of going in both pleasurable and uncomfortable directions. This can result in pleasurable tactile sensations but also enhances bodily aches and pains which one may not have previously been aware of to the point of extreme discomfort.
*'''[[Effect::Tactile enhancement]]''' - This effect is particularly prominent but capable of going in both pleasurable and uncomfortable directions. This can result in pleasurable tactile sensations but also enhances bodily aches and pains which one may not have previously been aware of to the point of extreme discomfort.
*'''[[Effect::Bodily control enhancement]]'''
*'''[[Effect::Bodily control enhancement]]'''
*'''[[Effect::Temperature regulation suppression]]'''{{citation needed}} - In terms of its effects on body temperature 2C-P is capable of causing large increases and decreases in temperature in a dose dependent manner. This can become extremely uncomfortable if not dangerous at larger doses due to the fever-like delirium it can induce.
*'''[[Effect::Temperature regulation suppression]]'''{{citation needed}} - 2C-P is reported to be able to cause large perceived increases and decreases in temperature in a dose dependent manner. This can become extremely uncomfortable if not dangerous at larger doses due to the fever-like delirium that is sometimes reported.
**'''[[Effect::Increased bodily temperature]]'''  
**'''[[Effect::Increased bodily temperature]]'''  
*'''[[Effect::Increased heart rate]]'''{{citation needed}}
*'''[[Effect::Increased heart rate]]'''{{citation needed}}
*'''[[Effect::Increased blood pressure]]'''{{citation needed}}
*'''[[Effect::Increased blood pressure]]'''{{citation needed}}
*'''[[Effect::Nausea]]''' -  Mild to extreme nausea is consistently reported when consumed in moderate to high dosages and either passes once the user has vomited or gradually fades by itself as the peak sets in.
*'''[[Effect::Nausea]]''' -  Mild to extreme nausea is consistently reported when consumed in moderate to high dosages and either passes once the user has vomited or gradually fades by itself as the peak sets in.
*'''[[Effect::Increased libido]]''' - A commonly felt physical component of the 2C-P trip is the way in which it heightens and enhances sexual arousal. When experienced, this sensation is not overwhelming or out of control but simply remains something that the user is constantly aware of. If sexual activities of any kind are engaged in, they are found to be immensely more pleasurable beyond anything that could be possible sober with orgasm becoming difficult to reach but completely possible to obtain. When obtained, the orgasm itself is capable of temporarily increasing the effects of the drug. This is most commonly experienced as visual effects dramatically increasing in a short yet powerful burst.  
*'''[[Effect::Increased libido]]''' - A common theme found in many 2C-P reports is the way in which it can heighten and enhance sexual arousal. When experienced, this sensation is not overwhelming or out of control but simply remains something that the user is constantly aware of. If sexual activities of any kind are engaged in, they are have been reported to be immensely more pleasurable than anything that can be achieved in a sober state.
*'''[[Effect::Pupil dilation]]'''
*'''[[Effect::Pupil dilation]]'''
*'''[[Effect::Teeth grinding]]'''
*'''[[Effect::Teeth grinding]]''' - A very common effect of 2C-P, and more pronounced with 2C-P than other 2C's or psychedelic substances in general. Can become very uncomfortable, especially with higher doses.


}}
}}
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*'''[[Effect::After images]]'''
*'''[[Effect::After images]]'''
*'''[[Effect::Symmetrical texture repetition]]'''
*'''[[Effect::Symmetrical texture repetition]]'''
*'''[[Effect::Colour shifting]]'''
*'''[[Effect::Color shifting]]'''
*'''[[Effect::Scenery slicing]]'''
*'''[[Effect::Scenery slicing]]'''
*'''[[Effect::Depth perception distortions]]'''
*'''[[Effect::Depth perception distortions]]'''


====[[Effect::Geometry]]====
====[[Effect::Geometry]]====
The visual geometry that is present throughout this trip can be described as more similar in appearance to that of [[Psilocetin|4-AcO-DMT]] or [[ayahuasca]] than that of [[LSD]], [[2C-B]] or [[2C-I]]. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in colour, sharp in their edges and equally rounded and angular in their corners. It gives off a contradictory natural and synthetic feel that at higher dosages are significantly more likely to result in states of [[Effect::8B Geometry|Level 8B]] visual geometry over [[Level 8A]]. There seems to be visual geometry that is distinct from [[2C-E]], [[psilocin]] and [[ayahuasca]] and can be described as faster moving and more intense in proportion to cognitive and physical effects than [[2C-E]].
The visual geometry present can be described as being more similar in appearance to that of [[Psilocetin|4-AcO-DMT]] or [[ayahuasca]] than that of [[LSD]], [[2C-B]] or [[2C-I]]. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colorful in scheme, glossy in color, sharp in their edges and equally rounded and angular in their corners. It gives off a contradictory natural and synthetic feel that at higher dosages are significantly more likely to result in states of [[Effect::8B Geometry|Level 8B]] visual geometry over [[Level 8A]]. There seems to be visual geometry that is distinct from [[2C-E]], [[psilocin]] and [[ayahuasca]] and can be described as faster moving and more intense in proportion to cognitive and physical effects than [[2C-E]].


====Hallucinatory states====
====Hallucinatory states====
2C-P produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the [[phenethylamines|phenethylamine]] family. These effects include:
2C-P produces a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other 2C-x [[phenethylamines]] such as [[2C-B]] or [[2C-I]]. These effects include:


*'''[[Effect::Machinescapes]]'''  
*'''[[Effect::Machinescapes]]'''  
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|{{effects/cognitive|
|{{effects/cognitive|
The cognitive effects of 2C-P have been described as both insightful and relatively normal in their thought processes up to moderate dosages, after which their confusing, and disorienting effects can increase considerably.
The cognitive effects of 2C-P have been described as both insightful and relatively normal in their thought processes up to moderate dosages, after which their confusing, and disorienting effects can increase considerably.
The total sum of these cognitive components regardless of the setting generally includes:


*'''[[Effect::Analysis enhancement]]'''
*'''[[Effect::Analysis enhancement]]'''
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==Toxicity and harm potential==
==Toxicity and harm potential==
{{toxicity}}
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
{{further|Research chemicals#Toxicity and harm potential|Responsible use #Hallucinogens}}
The toxicity and long-term health effects of recreational 2C-P use do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because 2C-P is a [[research chemical]] with very little history of human usage.  
The toxicity and long-term health effects of recreational 2C-P use do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because 2C-P is a [[research chemical]] with very little history of human usage.  


Anecdotal reports from human users suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption.
Anecdotal reports suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com/ Independent research] should always be done to ensure that a combination of two or more substances is safe before consumption.


It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance.
It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this substance.


===Tolerance and addiction potential===
===Tolerance and addiction potential===
2C-P is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating.  
As a [[serotonergic psychedelic]], 2C-P is considered to have a [[Addiction potential::low potential for abuse and dependence]].


Tolerance to the effects of 2C-P are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 2C-P presents cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 2C-P all psychedelics will have a reduced effect.
Tolerance to the effects of 2C-P are built [[Time to full tolerance::almost immediately after ingestion]]. After that, it takes about [[Time to half tolerance::3 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::7 days]] to be back at baseline (in the absence of further consumption). 2C-P produces cross-tolerance with [[Cross-tolerance::all [[psychedelic]]s]], meaning that after the consumption of 2C-P all psychedelics will have a reduced effect.


===Dangerous interactions===
===Dangerous interactions===
Line 127: Line 126:


==Legal status==
==Legal status==
Possession and sale of 2C-P is unscheduled in most countries.  
2C-P is currently unscheduled in most countries. This means it exists in a legal grey area in that it is not specifically illegal in most countries but individuals may still be charged for its possession under certain circumstances such as under analogue laws and with the intent to sell or consume.  


*'''United Kingdom''' - 2C-P is a Class A drug in the United Kingdom as a result of the phenethylamine catch-all clause.<ref>United Kingdom. (1977). Misuse of Drugs Act 1971 (S.I. 1977/1243). London: The Stationery Office Limited. Retrieved July 5, 2017, from http://www.legislation.gov.uk/uksi/1977/1243/made</ref>
*'''United States:''' 2C-P is a Schedule I drug.<ref>http://www.justice.gov/ola/views-letters/112/093011-ltr-re-hr1254-synthetic-drug-control-act-2011.pdf</ref>
*'''Austria:''' 2C-P is illegal to possess, produce and sell under the NPSG. (Neue-Psychoaktive-Substanzen-Gesetz Österreich){{citation needed}}
*'''Austria:''' 2C-P is illegal to possess, produce and sell under the NPSG. (Neue-Psychoaktive-Substanzen-Gesetz Österreich){{citation needed}}
*'''Canada:''' 2C-P would be considered Schedule III as it is a derivative of 2,5-dimethoxyphenethylamine.<ref>Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28</ref>
*'''China:''' As of October 2015, 2C-P is a controlled substance in China.<ref>{{cite web | url=http://www.sfda.gov.cn/WS01/CL0056/130753.html | title=关于印发《非药用类麻醉药品和精神药品列管办法》的通知 | publisher=China Food and Drug Administration | date=27 September 2015 | language=Chinese | accessdate=1 October 2015}}</ref>
*'''Denmark:''' 2C-P is added to the list of Schedule B controlled substances.<ref>https://www.retsinformation.dk/Forms/R0710.aspx?id=137169</ref>
*'''Denmark:''' 2C-P is added to the list of Schedule B controlled substances.<ref>https://www.retsinformation.dk/Forms/R0710.aspx?id=137169</ref>
*'''Germany''': On December 13, 2014 2C-P was added to the controlled substance act ("BtMG"), making it illegal to produce, sell or possess.<ref>Achtundzwanzigste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften (28. BtMÄndV)| http://www.buzer.de/gesetz/11392/a189949.htm</ref>
*'''Germany''': On December 13, 2014 2C-P was added to the controlled substance act ("BtMG"), making it illegal to produce, sell or possess.<ref>Achtundzwanzigste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften (28. BtMÄndV)| http://www.buzer.de/gesetz/11392/a189949.htm</ref>
*'''Latvia:''' 2C-P is a Schedule I controlled substance.<ref>Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086</ref>
*'''Latvia:''' 2C-P is a Schedule I controlled substance.<ref>Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086</ref>
*'''Switzerland:''' Possession, production and sale is illegal.<ref>http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html</ref>
*'''Switzerland:''' Possession, production and sale is illegal.<ref>http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html</ref>
*'''China''' - As of October 2015 2C-P is a controlled substance in China.<ref>{{cite web | url=http://www.sfda.gov.cn/WS01/CL0056/130753.html | title=关于印发《非药用类麻醉药品和精神药品列管办法》的通知 | publisher=China Food and Drug Administration | date=27 September 2015 | language=Chinese | accessdate=1 October 2015}}</ref>
*'''United Kingdom:''' 2C-P is a Class A drug in the United Kingdom as a result of the phenethylamine catch-all clause.<ref>United Kingdom. (1977). Misuse of Drugs Act 1971 (S.I. 1977/1243). London: The Stationery Office Limited. Retrieved July 5, 2017, from http://www.legislation.gov.uk/uksi/1977/1243/made</ref>
*'''Canada:''' 2C-P would be considered Schedule III as it is a derivative of 2,5-dimethoxyphenethylamine.<ref>Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28</ref>
*'''United States:''' 2C-P is a Schedule I drug.<ref>http://www.justice.gov/ola/views-letters/112/093011-ltr-re-hr1254-synthetic-drug-control-act-2011.pdf</ref>


==See also==
==See also==

Revision as of 23:39, 11 February 2019

Summary sheet: 2C-P
2C-P
Chemical Nomenclature
Common names 2C-P
Substitutive name 2,5-Dimethoxy-4-propylphenethylamine
Systematic name 2-(2,5-Dimethoxy-4-propylphenyl)ethanamine
Class Membership
Psychoactive class Psychedelic
Chemical class Phenethylamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



Oral
Dosage
Threshold 1 mg
Light 2 - 6 mg
Common 6 - 10 mg
Strong 10 - 16 mg
Heavy 16 mg +
Duration
Total 10 - 20 hours
Onset 1 - 3 hours
Come up 2 - 4 hours
Peak 4 - 8 hours
Offset 3 - 6 hours
After effects 8 - 48 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions


2,5-Dimethoxy-4-propylphenethylamine (also known as 2C-P) is a lesser-known psychedelic of the phenethylamine class. 2C-P is a relatively obscure member of the 2C-x family of psychedelic phenethylamines and is known to be one of the most potent, longest-lived, and dose-sensitive of the series.

2C-P was first synthesized and tested for human activity by Alexander Shulgin, who documented his findings in the 1991 book PiHKAL ("Phenethylamines I Have Known and Loved")[1]. The reports found in the 2C-P PiHKAL entry remark on its depth and long onset and duration of action, with the commentary section describing 16 mg as a clear overdose with physical consequences. The commentary also notes the small window separating an adequate dose from an excessive dose, suggesting it is relatively easy to overdose on.

User reports following the publication of PiHKAL tend to characterize 2C-P in terms of its unusually long duration, powerful, sometimes overwhelming visuals, and intense "body load" (such as persisting nausea, muscle tension and general bodily discomfort). 2C-P's head space and visuals have been described as possessing more similarities to alkylated 2C's like 2C-E than halogenated members like 2C-B or 2C-I. Some reports suggest it may be easier to experience agitation and delirium on 2C-P than other 2C's, perhaps owing to the ease in which it can be mishandled. As a result, it is considered to have a questionable safety profile.

Due its powerful effects and unusually long duration, 2C-P may be overly intense and difficult to use safely for those who are not already experienced with hallucinogens. It is strongly advised to use harm reduction practices if using this substance. Dosing practices like "eye-balling" (i.e. not using a reliable milligram scale) or non-oral routes of administration should especially be avoided.

Chemistry

2C-P or 2,5-dimethoxy-4-propylphenethylamine is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. 2C-P contains methoxy functional groups CH3O- attached to carbons R2 and R5 and a propyl chain attached to carbon R4 of the phenyl ring. 2C-P belongs to the 2C family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring.[2]

Pharmacology

Further information: Serotonergic psychedelic

2C-P's psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. However, the role of these interactions and how it results in the psychedelic experience continues to remain elusive.

Subjective effects

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Visual effects

Experience reports

Anecdotal reports which describe the effects of this compound within our experience index include:

Additional experience reports can be found here:

Toxicity and harm potential

This toxicity and harm potential section is a stub.

As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it.
Note: Always conduct independent research and use harm reduction practices if using this substance.

The toxicity and long-term health effects of recreational 2C-P use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 2C-P is a research chemical with very little history of human usage.

Anecdotal reports suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this substance.

Tolerance and addiction potential

As a serotonergic psychedelic, 2C-P is considered to have a low potential for abuse and dependence.

Tolerance to the effects of 2C-P are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 2C-P produces cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 2C-P all psychedelics will have a reduced effect.

Dangerous interactions

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

  • Tramadol - Tramadol lowers the seizure threshold[3] and psychedelics may act as triggers for seizures among those who are susceptible to them.[citation needed]
  • Stimulants - Stimulants affect many parts of the brain. Combined with psychedelics, stimulation can turn into uncontrollable anxiety, panic, thought loops and paranoia. This interaction may result in an elevated risk of psychosis.[citation needed]
  • Lithium - Lithium is often used as treatment for bipolar disorder. There is a large body of reports that indicate combining it with psychedelics results in a highly elevated risk of seizures and psychosis, possibly owing to its glutaminergic and GABAergic effects.[citation needed]

2C-P is currently unscheduled in most countries. This means it exists in a legal grey area in that it is not specifically illegal in most countries but individuals may still be charged for its possession under certain circumstances such as under analogue laws and with the intent to sell or consume.

  • Austria: 2C-P is illegal to possess, produce and sell under the NPSG. (Neue-Psychoaktive-Substanzen-Gesetz Österreich)[citation needed]
  • Canada: 2C-P would be considered Schedule III as it is a derivative of 2,5-dimethoxyphenethylamine.[4]
  • China: As of October 2015, 2C-P is a controlled substance in China.[5]
  • Denmark: 2C-P is added to the list of Schedule B controlled substances.[6]
  • Germany: On December 13, 2014 2C-P was added to the controlled substance act ("BtMG"), making it illegal to produce, sell or possess.[7]
  • Latvia: 2C-P is a Schedule I controlled substance.[8]
  • Switzerland: Possession, production and sale is illegal.[9]
  • United Kingdom: 2C-P is a Class A drug in the United Kingdom as a result of the phenethylamine catch-all clause.[10]
  • United States: 2C-P is a Schedule I drug.[11]

See also

Discussion

References

  1. https://erowid.org/library/books_online/pihkal/pihkal.shtml | PiHKAL
  2. http://isomerdesign.com/PiHKAL/read.php?id=36
  3. Talaie, H., Panahandeh, R., Fayaznouri, M. R., Asadi, Z., & Abdollahi, M. (2009). Dose-independent occurrence of seizure with tramadol. Journal of medical toxicology, 5(2), 63-67. doi:10.1007/BF03161089
  4. Controlled Drugs and Substances Act (S.C. 1996, c. 19) |http://laws-lois.justice.gc.ca/eng/acts/C-38.8/page-12.html#h-28
  5. "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015. 
  6. https://www.retsinformation.dk/Forms/R0710.aspx?id=137169
  7. Achtundzwanzigste Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften (28. BtMÄndV)| http://www.buzer.de/gesetz/11392/a189949.htm
  8. Noteikumi par Latvijā kontrolējamajām narkotiskajām vielām, psihotropajām vielām un prekursoriem (2,5-Dimetoksifeniletānamīni) | http://likumi.lv/doc.php?id=121086
  9. http://web.archive.org/web/20170329020935/https://www.admin.ch/opc/de/classified-compilation/20101220/index.html
  10. United Kingdom. (1977). Misuse of Drugs Act 1971 (S.I. 1977/1243). London: The Stationery Office Limited. Retrieved July 5, 2017, from http://www.legislation.gov.uk/uksi/1977/1243/made
  11. http://www.justice.gov/ola/views-letters/112/093011-ltr-re-hr1254-synthetic-drug-control-act-2011.pdf