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Compulsive redosing: Difference between revisions

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<onlyinclude>'''Compulsive redosing''' is the experience of a powerful and difficult to resist urge to continuously redose a [[psychoactive substance]] in an effort to increase or maintain the [[Subjective effects index|subjective effects]] which it induces.<ref>Everitt, B. J., & Robbins, T. W. (2005). Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nature neuroscience, 8(11), 1481. https://doi.org/10.1038/nn1579</ref><ref name=":0">Volkow, N. D., & Fowler, J. S. (2000). Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cerebral cortex, 10(3), 318-325. https://doi.org/10.1093/cercor/10.3.318</ref><ref name=":1">Hyman, S. E., & Malenka, R. C. (2001). Addiction and the brain: the neurobiology of compulsion and its persistence. Nature reviews neuroscience, 2(10), 695. https://doi.org/10.1038/35094560</ref>
<onlyinclude>'''Compulsive redosing''' is the experience of a powerful and difficult to resist urge to continuously redose a [[psychoactive substance]] in an effort to increase or maintain the [[Subjective effects index|subjective effects]] which it induces.<ref>Everitt, B. J., & Robbins, T. W. (2005). Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nature neuroscience, 8(11), 1481. https://doi.org/10.1038/nn1579</ref><ref name=":0">Volkow, N. D., & Fowler, J. S. (2000). Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cerebral cortex, 10(3), 318-325. https://doi.org/10.1093/cercor/10.3.318</ref><ref name=":1">Hyman, S. E., & Malenka, R. C. (2001). Addiction and the brain: the neurobiology of compulsion and its persistence. Nature reviews neuroscience, 2(10), 695. https://doi.org/10.1038/35094560</ref><ref name=":2" />


This effect is considerably more likely to manifest itself when the user has a large supply of the given substance within their possession. It can be partially avoided by pre-weighing dosages, not keeping the remaining material within sight, exerting self-control, and giving the compound to a trusted individual to keep until they deem it safe to return.
This effect is considerably more likely to manifest itself when the user has a large supply of the given substance within their possession. It can be partially avoided by pre-weighing dosages, not keeping the remaining material within sight, exerting self-control, and giving the compound to a trusted individual to keep until they deem it safe to return.


Compulsive redosing is often accompanied by other coinciding effects such as [[cognitive euphoria]], [[physical euphoria]], or [[anxiety suppression]] alongside of other effects which inhibit the clarity of one's decision-making processes such as [[disinhibition]], [[motivation enhancement]], and [[ego inflation]]. It is most commonly induced under the influence of [[dosage#common|moderate]] [[dosage|dosages]] of a wide variety of compounds, such as [[opioid|opioids]], [[stimulant|stimulants]],<ref name=":0" /><ref>Soussan, C., & Kjellgren, A. (2015). “Chasing the High”–Experiences of Ethylphenidate as Described on International Internet Forums. Substance abuse: research and treatment, 9, SART-S22495. https://doi.org/10.4137/SART.S22495</ref> [[GABAergic|GABAergics]],<ref name=":0" /> and [[GABAergic|entactogens]].<ref name=":1" /> However, it can also occur to a lesser extent under the influence of [[dissociative|dissociatives]] and [[cannabinoid|cannabinoids]].<ref name=":1" /></onlyinclude>
Compulsive redosing is often accompanied by other coinciding effects such as [[cognitive euphoria]], [[physical euphoria]], or [[anxiety suppression]] alongside of other effects which inhibit the clarity of one's decision-making processes such as [[disinhibition]], [[motivation enhancement]], and [[ego inflation]]. It is most commonly induced under the influence of [[dosage#common|moderate]] [[dosage|dosages]] of a wide variety of compounds, such as [[opioid|opioids]], [[stimulant|stimulants]],<ref name=":0" /><ref name=":2">Soussan, C., & Kjellgren, A. (2015). “Chasing the High”–Experiences of Ethylphenidate as Described on International Internet Forums. Substance abuse: research and treatment, 9, SART-S22495. https://doi.org/10.4137/SART.S22495</ref><ref>Olives, T. D., Orozco, B. S., & Stellpflug, S. J. (2012). Bath salts: the ivory wave of trouble. ''Western Journal of Emergency Medicine'', ''13''(1), 58. https://doi.org/10.5811/westjem.2011.6.6782</ref> [[GABAergic|GABAergics]],<ref name=":0" /> and [[GABAergic|entactogens]].<ref name=":1" /> However, it can also occur to a lesser extent under the influence of [[dissociative|dissociatives]] and [[cannabinoid|cannabinoids]].<ref name=":1" /></onlyinclude>
===Psychoactive substances===
===Psychoactive substances===
Substances which may cause this effect include:
Substances which may cause this effect include:

Revision as of 22:27, 19 December 2018

Compulsive redosing is the experience of a powerful and difficult to resist urge to continuously redose a psychoactive substance in an effort to increase or maintain the subjective effects which it induces.[1][2][3][4]

This effect is considerably more likely to manifest itself when the user has a large supply of the given substance within their possession. It can be partially avoided by pre-weighing dosages, not keeping the remaining material within sight, exerting self-control, and giving the compound to a trusted individual to keep until they deem it safe to return.

Compulsive redosing is often accompanied by other coinciding effects such as cognitive euphoria, physical euphoria, or anxiety suppression alongside of other effects which inhibit the clarity of one's decision-making processes such as disinhibition, motivation enhancement, and ego inflation. It is most commonly induced under the influence of moderate dosages of a wide variety of compounds, such as opioids, stimulants,[2][4][5] GABAergics,[2] and entactogens.[3] However, it can also occur to a lesser extent under the influence of dissociatives and cannabinoids.[3]

Psychoactive substances

Substances which may cause this effect include:

Experience reports

Anecdotal reports which describe this effect within our experience index include:

See also

References

  1. ↑ Everitt, B. J., & Robbins, T. W. (2005). Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nature neuroscience, 8(11), 1481. https://doi.org/10.1038/nn1579
  2. ↑ 2.0 2.1 2.2 Volkow, N. D., & Fowler, J. S. (2000). Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cerebral cortex, 10(3), 318-325. https://doi.org/10.1093/cercor/10.3.318
  3. ↑ 3.0 3.1 3.2 Hyman, S. E., & Malenka, R. C. (2001). Addiction and the brain: the neurobiology of compulsion and its persistence. Nature reviews neuroscience, 2(10), 695. https://doi.org/10.1038/35094560
  4. ↑ 4.0 4.1 Soussan, C., & Kjellgren, A. (2015). “Chasing the High”–Experiences of Ethylphenidate as Described on International Internet Forums. Substance abuse: research and treatment, 9, SART-S22495. https://doi.org/10.4137/SART.S22495
  5. ↑ Olives, T. D., Orozco, B. S., & Stellpflug, S. J. (2012). Bath salts: the ivory wave of trouble. Western Journal of Emergency Medicine, 13(1), 58. https://doi.org/10.5811/westjem.2011.6.6782
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