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5-MeO-DiBF: Difference between revisions

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==Subjective effects==
==Subjective effects==
{{Preamble/SubjectiveEffects}}
{{Preamble/SubjectiveEffects}}
===Physical effects===
{{effects/base
|{{effects/physical|
*'''[[Effect::Stimulation]]'''
*'''[[Effect::Spontaneous physical sensations]]''' -  The "body high" of 5-MeO-DiBF can be described as a motionless, constant, sharp and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the come up and hits its limit once the peak has been reached.
*'''[[Effect::Spontaneous physical sensations]]''' -  The "body high" of 5-MeO-DiBF can be described as a motionless, constant, sharp and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the come up and hits its limit once the peak has been reached.
*'''[[Effect::Increased heart rate]]'''
*'''[[Effect::Increased heart rate]]'''
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*'''[[Effect::Perception of decreased weight]]'''
*'''[[Effect::Perception of decreased weight]]'''
*'''[[Effect::Pupil dilation]]'''
*'''[[Effect::Pupil dilation]]'''
*'''[[Effect::Stimulation]]'''
*'''[[Effect::Tactile enhancement]]'''
*'''[[Effect::Tactile enhancement]]'''
*'''[[Effect::Temperature regulation suppression]]'''
*'''[[Effect::Temperature regulation suppression]]'''


===Cognitive effects===
}}
{{effects/visual|
====Enhancements====
*'''[[Effect::Colour enhancement]]'''
*'''[[Effect::Pattern recognition enhancement]]'''
*'''[[Effect::Visual acuity enhancement]]'''
 
====Distortions====
*'''[[Effect::Drifting]]''' ''([[Drifting#Melting|melting]], [[Drifting#Flowing|flowing]], [[Drifting#Breathing|breathing]] and [[Drifting#morphing|morphing]])'' - In comparison to other psychedelics, this effect can be described as simplistic, slow and smooth in motion, static in appearance and unrealistic in style.
*'''[[Effect::Colour shifting]]'''
*'''[[Effect::Tracers]]'''
 
<!-- ====[[effect::Geometry]]====
The visual geometry of this substance can be described as more similar in appearance to that of [[5-MeO-DALT]] or [[AMT]] than that of [[LSD]], [[2C-B]] or [[2C-I]]. It can be comprehensively described as unstructured in its organization, synthetic in geometric style, intricate in complexity, small in size, slow and smooth in motion, colourful in scheme, glossy in colour, equally blurred and sharp in its edges and equally rounded and angular in its corners. It gives off a synthetic feel that is less impressive than most of the "classical" psychedelics at any level. It has yet to be confirmed whether this compound results in either [[level 8A]] or [[level 8B]] geometry at heavy doses.-->
}}
|{{effects/cognitive|
The head space of 5-MeO-DiBF is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high doses.
The head space of 5-MeO-DiBF is described by many as one which is both insightful and relatively normal in its thought processes even at moderate to high doses.


Line 54: Line 70:
*'''[[Effect::Wakefulness]]'''
*'''[[Effect::Wakefulness]]'''


===Visual effects===
}}
====Enhancements====
{{effects/auditory|
*'''[[Effect::Colour enhancement]]'''
*'''[[Effect::Auditory enhancement]]'''
*'''[[Effect::Pattern recognition enhancement]]'''
*'''[[Effect::Auditory distortion]]'''
*'''[[Effect::Visual acuity enhancement]]'''
*'''[[Effect::Auditory hallucinations]]'''
 
}}
====Distortions====
}}
*'''[[Effect::Drifting]]''' ''([[Drifting#Melting|melting]], [[Drifting#Flowing|flowing]], [[Drifting#Breathing|breathing]] and [[Drifting#morphing|morphing]])'' - In comparison to other psychedelics, this effect can be described as simplistic, slow and smooth in motion, static in appearance and unrealistic in style.
*'''[[Effect::Colour shifting]]'''
*'''[[Effect::Symmetrical texture repetition]]'''
*'''[[Effect::Tracers]]'''
 
====[[effect::Geometry]]====
The visual geometry that is present throughout the experience can be described as more similar in appearance to that of [[5-MeO-DALT]] or [[AMT]] than that of [[LSD]], [[2C-B]] or [[2C-I]]. It can be comprehensively described as unstructured in its organization, synthetic in geometric style, intricate in complexity, small in size, slow and smooth in motion, colourful in scheme, glossy in colour, equally blurred and sharp in its edges and equally rounded and angular in its corners. It gives off a synthetic feel that is less impressive than most of the "classical" psychedelics at any level. It has yet to be confirmed whether this compound results in either [[level 8A]] or [[level 8B]] geometry at heavy doses.
 
===Auditory effects===
*'''[[Effect::Auditory enhancement|Enhancements]]'''
*'''[[Effect::Auditory distortion|Distortions]]'''
*'''[[Effect::Auditory hallucinations|Hallucinations]]'''


==Toxicity and harm potential==
==Toxicity and harm potential==

Revision as of 22:34, 10 February 2018

This page has not been fully approved by the PsychonautWiki administrators.

It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.

5-MeO-DiBF
Chemical Nomenclature
Common names 5-MeO-DiBF
Systematic name 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-diisopropyllethanamine
Class Membership
Psychoactive class Psychedelic
Chemical class Benzofuran
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



Oral
Dosage
Threshold 20 mg
Light 50 - 80 mg
Common 80 - 110 mg
Strong 110 - 140 mg
Heavy 140 mg +
Duration
Total 4 - 6 hours
Peak 30 - 60 minutes









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions
Summary sheet: 5-MeO-DiBF

5-Methoxy-N,N-diisopropylbenzofuranethylamine (also known as 5-MeO-DiBF) is a novel psychedelic substance of the benzofuran class that produces psychedelic and stimulating effects when administered.[1] It is a structural analog of 5-MeO-DiPT.

This compound has little to no history of human usage prior to its September 2015 release on the online research chemical market.

Very little is known about the pharmacological properties, metabolism, and toxicity of 5-MeO-DiBF. Due to its extreme novelty and unknown toxicity profile, it is highly advised that one use harm reduction practices if using this substance.

Chemistry

5-MeO-DiBF, or 5-methoxy-N,N-diisopropylbenzofuranethylamine, is a synthetic heterocyclic alkaloid molecule of the benzofuran class. Benzofuran is a bicyclic structure formed by the fusion of a benzene ring and a furan ring, a five member aromatic ring containing an oxygen substituent.

5-MeO-DiBF is composed of a benzofuran group attached at R3 to an amino group via an ethyl side chain. It is substituted at R5 of the benzofuran heterocycle with a methoxy (MeO) functional group CH3O−; it also contains two isopropyl chains bound to the terminal amine RN of its tryptamine backbone (DiBF).

The benzofuran group of 5-MeO-DiBF is closely related in structure to the indole found in tryptamines; benzofuran contains an oxygen group at the same location that indole contains a nitrogen. As such, 5-MeO-DiBF is closely related in structure to the psychedelic tryptamine 5-MeO-DiPT. 5-MeO-DiBF is the benzofuran analogue of 5-MeO-DiPT.

Pharmacology

Further information: Serotonergic psychedelic

5-MeO-DiBF likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from its efficacy at the 5-HT1A and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

This compound is several times less potent as a serotonin agonist than 5-MeO-DiPT. It has relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.[2][3]

Subjective effects

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Visual effects

Cognitive effects


Toxicity and harm potential

The toxicity and long-term health effects of recreational 5-MeO-DiBF use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 5-MeO-DiBF is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 5-MeO-DiBF suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

5-MeO-DiBF is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of 5-MeO-DiBF are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 5-MeO-DiBF presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 5-MeO-DiBF all psychedelics will have a reduced effect.

This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

5-MeO-DiBF is currently thought to be a legal grey area drug in many parts of the world. However, although it is easily accessible through the use of online research chemical vendors, this does not guarantee anyone to be immune from legal prosecution should they be found in possession of this substance as the legality is likely to vary from country to country.

  • United Kingdom - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.[4]

See also

References

  1. The Characterization of 2-(5-Methoxy-1-benzofuran-3-yl)-N,N-dimethylethanamine (5-MeO-BFE) and Differentiation from its N-Ethyl Analog | http://www.dea.gov/pr/microgram-journals/2012/mj9-1_39-45.pdf
  2. Benzofuran bioisosteres of hallucinogenic tryptamines (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/1534585
  3. Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/2139186
  4. Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted