2C-B-FLY

2C-B-FLY
Chemical Nomenclature
Common names	2C-B-FLY
Substitutive name	8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine
Systematic name	[[systematic name::2-(4-bromo-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-8-yl)ethanamine]]
Class Membership
Psychoactive class	Psychedelic
Chemical class	Phenethylamine / Benzodihydrodifuran
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Threshold 2 mg Light 5 - 10 mg Common 10 - 18 mg Strong 18 - 25 mg Heavy 25 mg + Duration Total 7 - 12 hours Onset 30 - 60 minutes Come up 1 - 2 hours Peak 3 - 5 hours Offset 2 - 3 hours After effects 6 - 24 hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Interactions

Summary sheet: 2C-B-FLY

2C-B-FLY is a psychedelic phenethylamine of the 2C-x family which was first synthesized by Aaron P. Monte in 1996. It produces psychedelic effects which typically last 6–8 hours, or up to 12 hours in larger doses. It presents effects which are similar to 2C-B, mescaline and 2C-D.

Very little is known about this substance, but it gained popularity around 2005 before becoming significantly less common after two deaths occurred in October 2009 after the ingestion of a substance that was mislabeled and sold as 2C-B-FLY but was actually bromo-DragonFLY.

It has recently become easily accessible again through online research chemical vendors where it is being sold as a designer drug.

Chemistry

2C-B-FLY is a substituted molecule of the phenethylamine and dihydrobenzofuran classes of drugs. 2C-B-FLY features a phenyl ring bound to an amino (NH₂) group through an ethyl chain and contains a bromine atom attached to carbon R₄ of the phenyl ring. 2C-B-FLY is an atypical psychedelic phenethylamine which is closely analogous to 2C-B; it is the dihydrofuran analog to 2C-B, where it incorporates the methoxy groups bound to R₂ and R₅ of 2C-B into five member dihydrofuran rings fused to the central benzene ring.

2C-B-FLY belongs to a group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” tetrahydrofuran rings fused on the opposite sides of the central benzene ring.

Pharmacology

Main article: Serotonergic psychedelic

2C-B-FLY's psychedelic effects are believed to come from its efficacy at the 5-HT_2A receptor as a partial agonist. It also has a high binding affinity for the 5-HT_1D, 5-HT_1E, 5-HT_1A, 5-HT_2B and 5-HT_2C receptors.

However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.

In comparison to 2C-B, this compound presents a significantly more pronounced body high, stronger visual effects, more complex geometry and more in-depth hallucinations which are comparable to mescaline, 2C-E or other phenethylamine psyhedelics.

Physical effects

The physical effects of 2C-B-FLY are comparable to that of traditional phenethylamines such as 2C-B, mescaline and 2C-D.

Many people have reported general gastrointestinal disturbances using compound which include diarrhoea, nausea, moderate to severe stomach bloating and general gassiness at moderate to heavy dosages. However, it is still considerably less physically taxing and far more comfortable than other drugs in the 2C-x family such as 2C-E and 2C-P. These effects are comparable to that of 5-MeO-MiPT, 2-C-T-7 and other compounds with highly suspected MAOI-altering properties, suggesting that 2C-B-FLY may potentially have such MAO-altering properties of its own, though this has yet to be confirmed.

• Spontaneous tactile sensations - The "body high" of 2C-B-FLY can be described as a pleasurable, warm, soft, all-encompassing and mild tingling sensation. This maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached. It is comparable to that of a milder mescaline, 2C-B or 2C-E experience.
• Stimulation and Sedation - At light dosages, this compound is generally stimulating but in a gentle, non-forceful manner similar to that of 2C-B or mescaline. However, at heavier dosages one may find the amount of stimulation to increase to uncomfortable degrees if not feeling significantly sedated in a manner similar to that of 2C-C or one of the many compounds in the 2C-T series, most prominently 2C-T-7.
• Nausea
• Bodily control enhancement
• Diarrhoea
• Pupil dilation
• Tactile enhancement
• Stomach bloating

Cognitive effects

It is worth noting that despite the potential cognitive effects of 2C-B-FLY, it tends to maintain a level of relatively normal and sober thought structure regardless of the subjective visual, physical and cognitive accompanying effects intensity. This leaves the user in control in a manner which would not be possible on many compounds such as 4-AcO-DMT, psilocin or LSD due to their accompanying confusion and delusions.

• Analysis enhancement
• Conceptual thinking
• Creativity enhancement
• Emotion enhancement
• Empathy, love, and sociability enhancement - This compound presents entactogenia on a level which is less intense than that of 2C-B or MDMA but similar in quality to that or mescaline or 2C-E.
• Increased libido
• Increased music appreciation
• Memory suppression
  • Ego death
• Mindfulness
• Novelty enhancement
• Personal bias suppression
• Spirituality enhancement
• Thought acceleration
• Time distortion
• Unity and interconnectedness
• Wakefulness

Visual effects

Enhancements

• Colour enhancement
• Pattern recognition enhancement
• Visual acuity enhancement

Distortions

• Drifting (melting, breathing, morphing and flowing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, intricate in appearance and unrealistic/cartoon-like in style. It is very comparable to that of 2C-B or mescaline.
• Colour shifting
• Depth perception distortions
• Perspective distortions
• Symmetrical texture repetition
• Tracers

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of mescaline, 2C-B and 2C-D than psilocin or ayahuasca. It can be comprehensively described through its style variations as intricate in complexity, abstract in form, synthetic in style, structured in organization, brightly lit and multicoloured in scheme, glossy in shading, flat in edges, large in size, fast in speed, smooth in motion, angular in corners, non-immersive in depth and consistent in intensity. They have a a contradictory combination of a very "natural" but also "neon digital" feel to them and at higher dosages are significantly more likely to result in states of level 8B visual geometry over level 8A.

Hallucinatory states

2C-B-FLY produces a full range of high level hallucinatory states in a fashion that is comparable to mescaline or 2C-E. This is more consistent and reproducible than that of many other commonly used psychedelics such as 2C-B or LSD. It tends to occur at heavier dosages and integrates seamlessly with the accompanying geometry. These effects generally include:

• Transformations
• Internal hallucinations (autonomous entities; settings, sceneries, and landscapes; alterations in perspective and scenarios and plots)

Auditory effects

• Enhancements
• Distortions
• Hallucinations

After effects

The effects which occur during the offset of a this compound are comparable to that of a mild stimulant. The experience generally feels negative and uncomfortable in comparison to the effects which occurred during its peak. This is often referred to as a "comedown" and may occur because of neurotransmitter depletion. Its effects commonly include:

• Headaches
• Diarrhoea
• Cognitive fatigue
• Motivation suppression
• Thought deceleration

Toxicity and harm potential

Main articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational 2C-B-FLY do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 2C-B-FLY is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 2C-B-FLY suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

2C-B-FLY is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of 2C-B-FLY are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 2C-B-FLY presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 2C-B-FLY all psychedelics will have a reduced effect.

Dangerous interactions

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

If 2C-B-FLY does indeed have its suspected MAOI effects, this could indicate that 2C-B-FLY is more likely to induce serotonin syndrome or general neurotransmitter overload (especially at high dosages) than other serotonergic psychedelics. This may make it dangerous to combine it with other MAOIs, stimulants and certain substances which releases neurotransmitters such as serotonin or dopamine. These substances include but are not limited to:

5-MeO-MiPT 2-C-T-7 AMT Ayahuasca Harmala alkaloids 2-AI 2-FMA 3-FPM 4-FA A-PVP Amphetamine Cocaine Ethylphenidate

Dehydroxyfluorafinil Isopropylphenidate MDAI MDMA Mephedrone Methamphetamine Methiopropamine Methylone Methylphenidate Modafinil Nicotine NM-2-AI Noopept

Legal issues

This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it.

• United States - 2C-B-FLY is unscheduled and uncontrolled in the United States. However, it may fall under the scope of the Federal Analog Act if it is intended for human consumption given its similarity to 2C-B.
• United Kingdom - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.

See also

• Responsible use
• Psychedelics
• Phenethylamines
• 2C-x
• 2C-B

External links

• 2C-B-FLY (Wikipedia)
• 2C-B-FLY (Erowid)
• 2C-B-FLY (TripSit)
• 2C-B-FLY (Bluelight)
• 2C-B-FLY (Isomer Design)