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Substituted tropanes: Difference between revisions

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==Chemistry==
==Chemistry==
{{chemistry}}
{{chemistry}}
Tropane alkaloids are molecules that contain a tropane ring in their structure.
Tropane alkaloids are molecules which contain a substituted tropane ring in their structure. Tropane is a nitrogen-containing bicyclic organic molecule, which consists of a piperidine and pyrrolidine ring fused at carbons R<sub>1</sub> and R<sub>5</sub>. It has additional methyl substitution at R<sub>N</sub>.
 
A tropane ring is a nitrogen-containing bicyclic organic molecule, which consists of a piperidine and pyrrolidine ring fused at carbons R<sub>1</sub> and R<sub>5</sub>. It has additional methyl substitution at R<sub>N</sub>.


==Pharmacology==
==Pharmacology==

Revision as of 08:12, 11 October 2016

General tropane molecule

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Tropane alkaloids are a class of chemicals that include compounds with psychoactive effects.

Chemistry

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Tropane alkaloids are molecules which contain a substituted tropane ring in their structure. Tropane is a nitrogen-containing bicyclic organic molecule, which consists of a piperidine and pyrrolidine ring fused at carbons R1 and R5. It has additional methyl substitution at RN.

Pharmacology

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Tropane alkaloids are mostly anti-cholinergics (antagonistic action on acetylcholine receptors) or stimulants (prevention of dopamine reuptake).

Examples

Tropane alkaloids are seen throughout organic chemistry and include psychoactive and anaesthetic compounds.

Anticholinergic drugs:

Stimulant drugs:

See also

References

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