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4-AcO-MET: Difference between revisions

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'''4-HO-MET''' ('''4-hydroxy-''N''-methyl-''N''-ethyltryptamine''', or '''metocin''', '''methylcybin''', '''Colour'''), is a lesser-known [[Psychedelics, dissociatives and deliriants|psychedelic drug]].  
'''4-Acetoxy-MET''' ('''4-Acetoxy-''N''-methyl-''N''-ethyltryptamine'''), also known as ''''''metacetin'''''' or '''4-AcO-MET''', is a [[psychedelic]] [[tryptamine]]. It is the acetate ester of [[4-HO-MET]], and a homologue of [[4-AcO-DMT]]. It is a novel compound with very little history of human use. It is sometimes sold as a [[research chemical]] by online retailers.


It is a structural− and functional analog of [[psilocin]] as well the 4-hydroxyl analog of [[methylethyltryptamine|MET]]. 4-HO-MET was first synthesized by [[Alexander Shulgin]]. In his book ''[[TiHKAL]]'' (''Tryptamines I Have Known and Loved''), the dosage is listed as 10-20 mg.<ref>{{CiteTiHKAL}}</ref> 4-HO-MET produces [[psilocin]]-like distortion of color, sound, and form. Very little data exists about the pharmacological properties, metabolism, and toxicity of 4-HO-MET. There have been no reports of deaths from 4-HO-MET, even though people have reported taking doses up to 150&nbsp;mg,<ref name='erowid OD experience'> {{cite web | url = http://www.erowid.org/experiences/exp.php?ID=71218 | title = Erowid Experience Vaults / Cosmic Mind Orgy | accessdate = 2014-02-25 | date = 2008-07-22 | publisher = [[Erowid]]}}</ref> more than an order of magnitude above the effective dose.<ref>http://www.erowid.org/experiences/exp.cgi?S1=436&S2=-1&C1=-1&Str=</ref>
It is expected that the compound is quickly [[hydrolysis|hydrolyzed]] into the free phenolic [[4-HO-MET]] by [[serum esterase]]s, but human studies concerning the metabolic fate of this drug are lacking.{{cn|date=May 2013}} There is  proof that this is a very active substance.{{cn|date=May 2013}}


==Chemistry==
==Chemistry==

Revision as of 22:13, 31 July 2014

4-AcO-MET
Chemical Nomenclature
Common names DMT, Dimethyltryptamine, Dmitri
Substitutive name N,N-Dimethyltryptamine
Systematic name 2-(1H-Indol-3-yl)-N,N-dimethylethanamine
Class Membership
Psychoactive class Psychedelic
Chemical class Tryptamine
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



⇣ Oral
Dosage
Bioavailability x"x" is not a number.% - y"y" is not a number.%[1]
Threshold x"x" is not a number. - mg
Light x"x" is not a number. - y"y" is not a number. mg
Common x"x" is not a number. - y"y" is not a number. mg
Strong x"x" is not a number. - y"y" is not a number. mg
Heavy x"x" is not a number. mg +
Duration
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Onset x"x" is not a number. - y"y" is not a number. minutes
Come up x"x" is not a number. - y"y" is not a number. minutes
Peak x"x" is not a number. - y"y" is not a number. hours
Offset x"x" is not a number. - y"y" is not a number. hours
After effects x"x" is not a number. - y"y" is not a number. hours


⇣ Sublingual
Dosage
Bioavailability x"x" is not a number.% - y"y" is not a number.%
Threshold x"x" is not a number. - mg
Light x"x" is not a number. - y"y" is not a number. mg
Common x"x" is not a number. - y"y" is not a number. mg
Strong x"x" is not a number. - y"y" is not a number. mg
Heavy x"x" is not a number. mg +
Duration
Total a"a" is not a number. - b"b" is not a number. hours
Onset a"a" is not a number. - b"b" is not a number. minutes
Come up a"a" is not a number. - b"b" is not a number. minutes
Peak a"a" is not a number. - b"b" is not a number. hours
Offset a"a" is not a number. - b"b" is not a number. hours
After effects a"a" is not a number. - b"b" is not a number. hours







DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

4-Acetoxy-MET (4-Acetoxy-N-methyl-N-ethyltryptamine), also known as 'metacetin' or 4-AcO-MET, is a psychedelic tryptamine. It is the acetate ester of 4-HO-MET, and a homologue of 4-AcO-DMT. It is a novel compound with very little history of human use. It is sometimes sold as a research chemical by online retailers.

It is expected that the compound is quickly hydrolyzed into the free phenolic 4-HO-MET by serum esterases, but human studies concerning the metabolic fate of this drug are lacking.Template:Cn There is proof that this is a very active substance.Template:Cn

Chemistry

Pharmacology

Subjective effects

Toxicity and Harm Potential

Lethal dosage

Tolerance and addition potential

See Also

References

  1. ↑ APA formatted citation.
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