This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
*'''[[Effect::Cognitive euphoria]]''' - Saffron is known to have powerful mood-enhancing effects and is often used as an antidepressant for this effect
*'''[[Effect::Cognitive euphoria]]''' - Saffron is known to have powerful mood-enhancing effects and is often used as an antidepressant for this effect <ref>https://jpnim.com/index.php/jpnim/article/view/e110222</ref>
*'''[[Effect::Focus enhancement]]'''
*'''[[Effect::Focus enhancement]]''' - Saffron is shown to have similar efficacy to [[methylphenidate]] in treating ADHD <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9573091/</ref>
*'''[[Effect::Emotion enhancement]]''' - Saffron is often used to treat anhedonia
*'''[[Effect::Emotion enhancement]]''' - Saffron is often used to treat anhedonia <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397008/</ref>
*'''[[Effect::Emotion suppression]]''' - This effect is similar to but milder than the emotion suppression produced by stimulants like [[methylphenidate]]
*'''[[Effect::Emotion suppression]]''' - This effect is similar to but milder than the emotion suppression produced by stimulants like [[methylphenidate]]
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Addiction suppression]]'''
*'''[[Effect::Addiction suppression]]''' - Saffron is found to suppress symptoms of opioid withdrawal and reduce tolerance to opioids <ref>https://www.tandfonline.com/doi/abs/10.1080/00952990.2020.1865995</ref>
*'''[[Effect::Empathy, affection, and sociability enhancement]]'''
*'''[[Effect::Empathy, affection, and sociability enhancement]]'''<ref>https://www.frontiersin.org/articles/10.3389/fnut.2020.606124/full</ref>
*'''[[Effect::Thought acceleration]]'''
*'''[[Effect::Thought acceleration]]'''
*'''[[Effect::Ego inflation]]'''
*'''[[Effect::Ego inflation]]'''
*'''[[Effect::Irritability]]''' - This effect is uncommon but can occur at higher doses
*'''[[Effect::Irritability]]''' - This effect is uncommon but can occur at higher doses
*'''[[Effect::Wakefulness]]''' or '''[[Effect::Sleepiness]]'''
*'''[[Effect::Wakefulness]]''' or '''[[Effect::Sleepiness]]'''
Revision as of 18:27, 12 September 2023
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WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.
DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Saffron has a complex mechanism of action, and is shown to be a serotonin-dopamine-norepinephrine reuptake inhibitor, a monoamine oxidase A & B inhibitor, an acetylcholinesterase inhibitor, an NMDA antagonist, and a GABAa agonist. [2]
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
Physical effects
If applicable, a brief paragraph summary of the substance's physical effects may be included here.
You may select physical effects to add below here.
Stimulation - Saffron typically is stimulating in a similar but weaker manner to substances such as methylphenidate, and encourages physical activity
If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.
You may select from a list of cognitive effects to add below here.
Cognitive euphoria - Saffron is known to have powerful mood-enhancing effects and is often used as an antidepressant for this effect [5]
Time distortion - Saffron can sometimes cause time compression in a similar manner to stimulants like methylphenidate but milder
Auditory effects
If applicable, a brief paragraph summary of the substance's auditory effects may be included here.
You may select from a list of auditory effects to add below here.
If applicable, a brief paragraph summary of the substance's multisensory effects may be included here.
You may select from a list of multisensory effects to add below here.
If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.
You may select from a list of transpersonal effects to add below here.
This toxicity and harm potential section is a stub.
As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.
Warning:Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).
Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.
