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Substituted piperazines: Difference between revisions

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{{stub}}
{{stub}}
[[File:Piperazine.svg|thumb|right|100px||The structure of the piperazine molecule]]
[[File:Piperazine.svg|thumb|right|100px||The structure of the piperazine molecule]]
'''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects.
'''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects. They can be divided into two classes, the benzylpiperazines such as [[BZP]] itself, and its methylenedioxy analogue [[MDBZP]], and the phenylpiperazines [[mCPP]], [[TFMPP]], and [[MeOPP]]. Some deaths have rarely occurred when consuming BZP, it can increase chances of having seizures.


==Chemistry==
==Chemistry==
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Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring.
Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring.


==Examples==
<div class="flex-panel">
*[[BZP]]
    <div class="flex-column">
*[[mCPP]]
<div class="panel radius">
*[[TFMPP]]
<h3 class="panel-header">Recreational Piperazines</h3>
 
<ul class="featured-table">
<li class="featured list-item">
*[[2C-B-BZP]]
*[[3C-PEP]]
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'')
*[[BZP]] (''Benzylpiperazine'')
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'')
*[[DBZP]] (''1,4-Dibenzylpiperazine'')
*[[MBZP]] (''4-Methyl-1-benzylpiperazine'')
*[[MDBZP]] (''Methylenedioxybenzylpiperazine'')
*[[mCPP]] (''3-Chlorophenylpiperazine'')
*[[MDBZP]] (''3,4-Methylenedioxy-1-benzylpiperazine'')
*[[MeOP]] (''Methoxypiperamide'')
*[[MeOPP]] (''para-methoxyphenylpiperazine'')
*[[MT-45]] (''1-cyclohexyl-4-(1,2-diphenylethyl)piperazine'')
*[[mTFMPP]]
*[[oCPP]] (''2-Chlorophenylpiperazine'')
*[[oMPP]] (''2-Methylphenylpiperazine'')
*[[oMeOPP]] (''2-Methoxyphenylpiperazine'')
*[[oTFMPP]]
*[[pCPP]] (''4-Chlorophenylpiperazine'')
*[[pFPP]] (''4-Fluorophenylpiperazine'')
*[[pTFMPP]]
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'')
</li>
</ul>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Benzylpiperazines</h3>
 
<ul class="featured-table">
<li class="featured list-item">
*[[2C-B-BZP]]
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'')
*[[Befuraline]]
*[[Bifeprunox]]
*[[Buclizine]]
*[[BZP]] (''Benzylpiperazine'')
*[[Chlorbenzoxamine]]
*[[DBZP]]
*[[DF-MDBP]] (''Difluoromethylenedioxybenzylpiperazine'')
*[[Fipexide]]
*[[Imatinib]]
*[[MBZP]]
*[[MDBZP]]
*[[Meclozine]]
*[[MeOP]] (''Methoxypiperamide'')
*[[Piberaline]]
*[[Piribedil]]
*[[RN-1747]]
*[[Sunifiram]]
*[[Trimetazidine]]
*[[TFMCPP]] (''3-Trifluoromethyl-4-chlorophenylpiperazine'')
*[[Vesnarinone]]
</li>
</ul>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Phenylpiperazines</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[2C-B-PP]] (''2,5-dimethoxy-4-bromophenylpiperazine'')
*[[3,4-CFP]] (''3-Chloro-4-fluorophenylpiperazine'')
*[[3C-PEP]]
*[[Acaprazine]]
*[[Aripiprazole]] (''Abilify'')
*[[Bifeprunox]]
*[[Brexpiprazole]]
*[[Cariprazine]]
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'')
*[[Elopiprazole]]
*[[Enciprazine]]
*[[Enpiprazole]]
*[[Ensaculin]]
*[[Etoperidone]]
*[[Flesinoxan]]
*[[Lorpiprazole]]
*[[Mepiprazole]]
*[[mCPP]] (''3-Chlorophenylpiperazine'')
*[[mMeOPP]] (''3-Methoxyphenylpiperazine'')
*[[Naluzotan]]
*[[Naphthylpiperazine]]
*[[Nefazodone]]
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'')
*[[Tolpiprazole]]
*[[Trazodone]]
*[[Vilazodone]]
*[[Vortioxetine]]
</li>
</ul>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Pyrimidinylpiperazine</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[Buspirone]]
*[[Dasatinib]]
*[[Eptapirone]]
*[[Gepirone]]
*[[Ipsapirone]]
*[[Piribedil]]
*[[Quipazine]]
*[[Revospirone]]
*[[Tandospirone]]
*[[Tirilazad]]
*[[Umespirone]]
*[[Zalospirone]]
</li>
</ul>
</div>
</div>
</div>
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Pyridinylpiperazine</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[Azaperone]]
*[[Atevirdine]]
*[[Delavirdine]]
*[[Mirtazapine]]
*[[ORG-12962]]
*[[ORG-37684]]
</li>
</ul>
</div>
</div>
</div>
 
 
<div class="flex-column">
<div class="panel radius">
<h3 class="panel-header">Other</h3>
<ul class="featured-table">
<li class="featured list-item">
*[[AD-1211]]
*[[AP-238]]
*[[Azaprocin]]
*[[Buclizine]]
*[[Bucinnazine]] (''AP-237'')
*[[Cetirizine]] (''Zyrtec'')
*[[Chlorcyclizine]]
*[[Cinnarizine]]
*[[Cyclizine]]
*[[Diphenpipenol]]
*[[Etodroxizine]]
*[[Flunarizine]]
*[[Homochlorcyclizine]]
*[[Hydroxyzine]]
*[[Meclizine]]
*[[MT-45]] (''IC-6'')
*[[NSI-189]]
*[[Oxatomide]]
*[[Perospirone]]
*[[Pipoxizine]]
*[[Tiospirone]]
*[[Unifiram]]
 
</li>
</ul>
</div>
</div>
</div>


==Pharmacology==
==Pharmacology==
Line 22: Line 196:


==External links==
==External links==
*[Piperazine (Wikipedia)https://en.wikipedia.org/wiki/Piperazine]
*[https://en.wikipedia.org/wiki/Substituted_piperazine Substituted piperazine (Wikipedia)]
*[https://en.wikipedia.org/wiki/Substituted_piperazine Substituted piperazine (Wikipedia)]
*[https://erowid.org/chemicals/piperazines/piperazines.shtml Piperazines (Erowid Vault)]


==References==
==References==
{{references}}
{{references}}
[[Category:Chemical class]]
[[Category:Piperazine|*]]

Latest revision as of 10:10, 24 May 2022

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

The structure of the piperazine molecule

Substituted piperazines refers to a class of chemicals that typically have stimulant effects. They can be divided into two classes, the benzylpiperazines such as BZP itself, and its methylenedioxy analogue MDBZP, and the phenylpiperazines mCPP, TFMPP, and MeOPP. Some deaths have rarely occurred when consuming BZP, it can increase chances of having seizures.

Chemistry

This chemistry section is incomplete.

You can help by adding to it.

Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R1 and R4 of the ring.

Recreational Piperazines

    • 2C-B-BZP
    • 3C-PEP
    • 3-Me-BZP (3-Methylbenzylpiperazine)
    • BZP (Benzylpiperazine)
    • DCPP (2,3-Dichlorophenylpiperazine)
    • DBZP (1,4-Dibenzylpiperazine)
    • MBZP (4-Methyl-1-benzylpiperazine)
    • MDBZP (Methylenedioxybenzylpiperazine)
    • mCPP (3-Chlorophenylpiperazine)
    • MDBZP (3,4-Methylenedioxy-1-benzylpiperazine)
    • MeOP (Methoxypiperamide)
    • MeOPP (para-methoxyphenylpiperazine)
    • MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine)
    • mTFMPP
    • oCPP (2-Chlorophenylpiperazine)
    • oMPP (2-Methylphenylpiperazine)
    • oMeOPP (2-Methoxyphenylpiperazine)
    • oTFMPP
    • pCPP (4-Chlorophenylpiperazine)
    • pFPP (4-Fluorophenylpiperazine)
    • pTFMPP
    • TFMPP (3-Trifluoromethylphenylpiperazine)

Benzylpiperazines

Phenylpiperazines

Pyrimidinylpiperazine

Pyridinylpiperazine


Other

Pharmacology

This pharmacology section is incomplete.

You can help by adding to it.

Piperazines typically have stimulant effects.

See also

References

This article does not cite enough references.

You can help by adding some.

Retrieved from "http://psy.st/w/index.php?title=Substituted_piperazines&oldid=129126"