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Salvinorin B methoxymethyl ether: Difference between revisions

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{{Experience reports|erowid_experience_substance_label=Salvinorin B Ethoxymethyl Ether}}
 
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===Experience reports===
===Experience reports===
There are currently no anecdotal reports which describe the effects of this compound within our [[experience index]]. Additional experience reports can be found here:
{{Experience reports|erowid_experience_substance_label=Salvinorin B Ethoxymethyl Ether}}
 
*[https://www.erowid.org/experiences/subs/exp_Salvinorin_B_Ethoxymethyl_Ether.shtml Erowid Experience Vaults: Salvinorin B methoxymethyl ether]


==See also==
==See also==
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*[https://en.wikipedia.org/wiki/Salvinorin_B_methoxymethyl_ether Salvinorin B methoxymethyl ether (Wikipedia)]
*[https://en.wikipedia.org/wiki/Salvinorin_B_methoxymethyl_ether Salvinorin B methoxymethyl ether (Wikipedia)]
*[https://www.erowid.org/chemicals/salvinorin_b_ethoxymethyl_ether/ Salvinorin B methoxymethyl ether (Erowid Vault)]
*[https://www.erowid.org/chemicals/salvinorin_b_ethoxymethyl_ether/ Salvinorin B methoxymethyl ether (Erowid Vault)]
*[https://isomerdesign.com/PiHKAL/explore.php?id=2842 Salvinorin B methoxymethyl ether (TiHKAL / Isomer Design)]
*[https://isomerdesign.com/PiHKAL/explore.php?id=2842 Salvinorin B methoxymethyl ether (Isomer Design)]


==References==
==References==

Latest revision as of 14:22, 2 July 2025

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Summary sheet: Salvinorin B methoxymethyl ether
Salvinorin B methoxymethyl ether
Chemical Nomenclature
Substitutive name Salvinorin B
Systematic name methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
Class Membership
Psychoactive class Hallucinogen
Chemical class Salvinorin
Interactions


Salvinorin B methoxymethyl ether (2-O-methoxymethylsalvinorin B, or 2-MMSB) is a semi-synthetic analogue of the natural product Salvinorin A which is used in scientific research. It has a longer duration of action of around 2–3 hours, compared to less than 30 minutes for salvinorin A, and has increased affinity and potency at the κ-opioid receptor. Like the related compound herkinorin, salvinorin B methoxymethyl ether is made from salvinorin B, which is most conveniently made from salvinorin A by deacetylation, as while both salvinorin A and salvinorin B are found in the plant Salvia divinorum, salvinorin A is present in larger quantities.

Salvinorin B methoxymethyl ether has a Ki of 0.60 nM at the κ opioid receptor, and is around five times more potent than salvinorin A in animal studies, although it is still only half as potent as its stronger homolog salvinorin B ethoxymethyl ether.

Experience reports

There are currently 0 experience reports describing the effects of this substance in our experience index. You can also submit your own experience report using the same link.

Additional experience reports can be found here:

See also

References

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