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Risperidone: Difference between revisions

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{{Experience reports|erowid_experience_substance_label=Pharms - Risperidone}}
 
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{{effects/base
{{effects/base
|{{effects/physical|
|{{effects/physical|
*'''[[Effect::Sedation]]'''
*'''[[Effect::Appetite enhancement]]'''
*'''[[Effect::Sedation]]''' - Risperidone produces strong sedation and can result in an overwhelmingly lethargic state. At higher levels, risperidone can cause users to suddenly feel as if they are extremely sleep deprived and have not slept for days, forcing them to sit down and generally feel as if they are constantly on the verge of passing out instead of engaging in physical activities. This sense of sleep deprivation increases proportional to dosage and eventually becomes powerful enough to force a person into complete unconsciousness.
*'''[[Effect::Dizziness]]'''
*'''[[Effect::Dizziness]]'''
*'''[[Effect::Decreased libido]]'''
*'''[[Effect::Increased heart rate]]'''
*'''[[Effect::Motor control loss]]'''
*'''[[Effect::Motor control loss]]'''
 
*'''[[Effect::Nausea suppression]]'''
}}
}}


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The general head space of risperidone is often described as one of sleepiness, emptiness, apathy, stupor and catatonia. The specific cognitive effects can be broken down into several components which progressively intensify proportional to dosage. These are described below and generally include:
The general head space of risperidone is often described as one of sleepiness, emptiness, apathy, stupor and catatonia. The specific cognitive effects can be broken down into several components which progressively intensify proportional to dosage. These are described below and generally include:
*'''[[Effect::Amnesia]]'''
*'''[[Effect::Amnesia]]'''
*'''[[Effect::Anxiety suppression]]'''
*'''[[Effect::Analysis suppression]]'''
*'''[[Effect::Apathy]]'''
*'''[[Effect::Creativity suppression]]'''
*'''[[Effect::Language suppression]]'''
*'''[[Effect::Emotion suppression]]'''
*'''[[Effect::Focus suppression]]'''
*'''[[Effect::Focus suppression]]'''
*'''[[Effect::Sleepiness]]'''
*'''[[Effect::Sleepiness]]'''
*'''[[Effect::Thought deceleration]]'''
*'''[[Effect::Thought deceleration]]'''
*'''[[Effect::Motivation suppression]]'''
*'''[[Effect::Appetite enhancement]]'''
}}
}}


}}
}}
===Experience reports===
===Experience reports===
There are currently no anecdotal reports which describe the effects of this compound within our [[experience index]]. Additional experience reports can be found here:
{{Experience reports|erowid_experience_substance_label=Pharms - Risperidone}}
* [https://www.erowid.org/experiences/subs/exp_Pharms_Risperidone.shtml Erowid Experience Vaults: Risperidone]


==Toxicity and harm potential==
==Toxicity and harm potential==
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==Legal status==
==Legal status==
*'''United Kingdom:''' Risperidone is available only through prescription.
 
*'''United States:''' Risperidone is available only through prescription.
*'''Australia:''' Risperidone is available only through prescription.{{citation needed}}
*'''Australia:''' Risperidone is available only through prescription.
*'''Germany:''' Risperidone is a prescription medicine, according to Anlage 1 AMVV.<ref>{{Citation | title=Anlage 1 AMVV - Einzelnorm | url=https://www.gesetze-im-internet.de/amvv/anlage_1.html}}</ref>
*'''Switzerland:''' Risperidone is listed as a "Abgabekategorie B" pharmaceutical, which requires a prescription.<ref>https://compendium.ch/product/81388-risperdal-filmtabl-0-5-mg</ref>
*'''United Kingdom:''' Risperidone is available only through prescription.{{citation needed}}
*'''United States:''' Risperidone is available only through prescription.{{citation needed}}


==See also==
==See also==
*[[Responsible use]]
*[[Responsible use]]
*[[Antipsychotic]]
*[[Antipsychotic]]
*[[Quetiapine]]
*[[Quetiapine]]
*[[Depressant]]
*[[Depressant]]
==External links==
==External links==
*[https://en.wikipedia.org/wiki/Risperidone Risperidone (Wikipedia)]
*[https://en.wikipedia.org/wiki/Risperidone Risperidone (Wikipedia)]
*[https://www.erowid.org/pharms/risperidone/ Risperidone (Erowid Vault)]
*[https://www.erowid.org/pharms/risperidone/ Risperidone (Erowid Vault)]
*[https://isomerdesign.com/PiHKAL/explore.php?id=9522 Risperidone (TiHKAL / Isomer Design)]
*[https://isomerdesign.com/PiHKAL/explore.php?id=9522 Risperidone (TiHKAL / Isomer Design)]
*[https://go.drugbank.com/drugs/DB00734 Risperidone (DrugBank)]


==References==
==References==
{{references}}<references/>
{{references}}<references />
[[Category:Psychoactive substance]]
[[Category:Psychoactive substance]]
[[Category:Substance]]
[[Category:Benzisoxazole]]
[[Category:Piperidine]]
[[Category:Antihistamine]]
[[Category:Antipsychotic]]
[[Category:Antipsychotic]]

Latest revision as of 14:24, 2 July 2025

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

Summary sheet: Risperidone
Risperidone
Chemical Nomenclature
Common names Risperdal
Substitutive name Risperidone
Systematic name 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Class Membership
Psychoactive class Antipsychotic
Chemical class Benzisoxazole
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



Oral
Dosage
Threshold 0.25 mg
Light 0.5 - 1 mg
Common 1 - 3 mg
Strong 3 - 6 mg
Heavy 6 mg +
Duration
Total 12 - 20 hours
Onset 20 - 60 minutes
Peak 2 - 8 hours
Offset 2 - 4 hours
After effects 12 - 24 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions


Risperidone (also known as Risperdal) is an atypical antipsychotic medication of the benzisoxazole chemical class. Risperidone is prescribed for bipolar disorder, autism, and psychotic disorders, such as in schizophrenia. It is sometimes used as a sedative to reduce the effects of psychedelics like LSD and to induce sleepiness. Benzodiazepines are also used for this purpose.

Chemistry

This chemistry section is incomplete.

You can help by adding to it.

Pharmacology

This pharmacology section is incomplete.

You can help by adding to it.

Risperidone has a complex pharmacology, but its main mechanism of action is as a D2 dopaminergic receptor antagonist. This means that it blocks dopamine from binding to the receptor, meanwhile not activating it. [citation needed] It also blocks most of the serotonin receptors, being an inverse agonist at the 5-HT2A, 5-HT2B, and 5-HT2C serotonin receptors.[citation needed] Risperidone has the strongest affinity to the 5-HT2A receptor.[citation needed] On top of that, it acts as an irreversible antagonist at the 5-HT7 serotonin receptor. Its hypnotic effects come from the blockade of dopamine D2 receptors.

Subjective effects

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

Cognitive effects

Experience reports

There are currently 0 experience reports describing the effects of this substance in our experience index. You can also submit your own experience report using the same link.

Additional experience reports can be found here:

Toxicity and harm potential

This toxicity and harm potential section is a stub.

As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it.
Note: Always conduct independent research and use harm reduction practices if using this substance.

  • Australia: Risperidone is available only through prescription.[citation needed]
  • Germany: Risperidone is a prescription medicine, according to Anlage 1 AMVV.[1]
  • Switzerland: Risperidone is listed as a "Abgabekategorie B" pharmaceutical, which requires a prescription.[2]
  • United Kingdom: Risperidone is available only through prescription.[citation needed]
  • United States: Risperidone is available only through prescription.[citation needed]

See also

References

This article does not cite enough references.

You can help by adding some.