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Template:SubstanceBox/Melatonin: Difference between revisions
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>Unity Corrected bioavailability to 15% with a reference. Adjusted dose and duration values. Removed sedative classification. |
>Isaak Time to peak concentration is 60+-30 minutes and half life is 60+-10minutes according to linked study |
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<!-- Nomenclature --> | <!-- Nomenclature --> | ||
|NameCommon=Melatonin | |NameCommon=[[common name::Melatonin]] | ||
|NameSubstitution=N-Acetyl-5-methoxytryptamine | |NameSubstitution=N-Acetyl-5-methoxytryptamine | ||
|NameSystematic=N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide | |NameSystematic=N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide | ||
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|OralROA_Collapsed=false | |OralROA_Collapsed=false | ||
|OralROA_Caption= | |OralROA_Caption= | ||
|OralROA_Bioavailability=[[Oral min bioavailability::15]]% | |OralROA_Bioavailability=[[Oral min bioavailability::15]]%%<ref>{{cite journal | vauthors=((DeMuro, R. L.)), ((Nafziger, A. N.)), ((Blask, D. E.)), ((Menhinick, A. M.)), ((Bertino, J. S.)) | journal=The Journal of Clinical Pharmacology | title=The Absolute Bioavailability of Oral Melatonin | volume=40 | issue=7 | pages=781–784 | date= July 2000 | url=http://doi.wiley.com/10.1177/00912700022009422 | issn=00912700 | doi=10.1177/00912700022009422}}</ref> | ||
|OralROA_Threshold=[[Oral threshold dose::0.25]] [[Oral dose units::mg]] | |OralROA_Threshold=[[Oral threshold dose::0.25]] [[Oral dose units::mg]] | ||
|OralROA_Light=[[Oral min light dose::0.5]] - [[Oral max light dose::1]] mg | |OralROA_Light=[[Oral min light dose::0.5]] - [[Oral max light dose::1]] mg | ||
| Line 61: | Line 61: | ||
|OralROA_TimelineFile= | |OralROA_TimelineFile= | ||
|OralROA_TimelineWidth= | |OralROA_TimelineWidth= | ||
|OralROA_Duration=[[Oral min total time:: | |OralROA_Duration=[[Oral min total time::3]] - [[Oral max total time::6]] [[Oral total time units::hours]] | ||
|OralROA_Onset=[[Oral min onset time::5]] - [[Oral max onset time::20]] [[Oral onset time units::minutes]] | |OralROA_Onset=[[Oral min onset time::5]] - [[Oral max onset time::20]] [[Oral onset time units::minutes]] | ||
|OralROA_Peak= | |OralROA_Comeup=[[Oral min comeup time::20]] - [[Oral max comeup time::70]] [[Oral comeup time units::minutes]] | ||
|OralROA_Offset= | |OralROA_Peak=[[Oral min peak time::1]] - [[Oral max peak time::2]] [[Oral peak time units::hours]] | ||
|OralROA_Offset=[[Oral min offset time::2]] - [[Oral max offset time::3]] [[Oral offset time units::hours]] | |||
|OralROA_Aftereffects= | |OralROA_Aftereffects= | ||
}} | }} | ||
Latest revision as of 06:19, 15 January 2025
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| Chemical Nomenclature | |||||||||||||||||||||||||||||||||
| Common names | Melatonin | ||||||||||||||||||||||||||||||||
| Substitutive name | N-Acetyl-5-methoxytryptamine | ||||||||||||||||||||||||||||||||
| Systematic name | N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide | ||||||||||||||||||||||||||||||||
| Class Membership | |||||||||||||||||||||||||||||||||
| Psychoactive class | Oneirogen | ||||||||||||||||||||||||||||||||
| Chemical class | Tryptamine | ||||||||||||||||||||||||||||||||
| Routes of Administration | |||||||||||||||||||||||||||||||||
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- ↑ DeMuro, R. L., Nafziger, A. N., Blask, D. E., Menhinick, A. M., Bertino, J. S. (July 2000). "The Absolute Bioavailability of Oral Melatonin". The Journal of Clinical Pharmacology. 40 (7): 781–784. doi:10.1177/00912700022009422. ISSN 0091-2700.