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{{SubstanceBox/3MMA}}
{{SubstanceBox/3-MMA}}
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'''3-MMA''' (also known as ''''3,N-Dimethylamphetamine''', '''Emma''', '''3-Me-Ma''' or '''3-Methyl-Methamphetamine''') is a [[stimulant]] substance of the [[amphetamines|amphetamine class]]. It was first synthesized 2020 by a research chemical vendor called "Juklis Lab"<ref>[https://juklislab.com/3mma]</ref>{{citation needed}}
3MMA also known as 3-Me-Ma or 3-Methyl-Methamphetamine (not to be confused with 3-Methoxy-methamphetamine) is a very new compound of the family of the [[Methamphetamine]]. Other names are 3,N-Dimethylamphetamine and Emma. It was first synthesized very recently, circa 2020, by the Juklis Lab (or so they say)<ref>[https://juklislab.com/3mma]</ref>
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
People refer to this substance as a little [[Methamphetamine]] as its effects are not so intense and its duration is shorter. It is mentioned as well that the comedown effects are mild.
==Chemistry==
3-MMA is the β-deketo analogue of 3MMC.
It is a triple releaser as it produces its effects by increasing levels of the neurotransmitters dopamine, norepinephrine and serotonin, but the release of serotonin is not as prominent as with the other two.
==History and culture==
{{historyStub}}
==Chemistry==
{{chemistry}}
==Pharmacology==
==Pharmacology==
{{pharmacology}}
3-MMA exerts its effects by increasing the signaling activity of [[neurotransmitters]] [[norepinephrine]], [[dopamine]] and to a lesser degree [[serotonin]].
==Subjective effects==
==Subjective effects==
{{EffectStub}}
{{Preamble/SubjectiveEffects}}
{{Preamble/SubjectiveEffects}}
{{effects/base
{{effects/base
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You may select physical effects to add below [[Subjective effect index#Physical effects|here]].
You may select physical effects to add below [[Subjective effect index#Physical effects|here]].
*'''[[Effect::Physical effect]]'''
*'''[[Effect::Stimulation]]''' - sort of a warm stimulation due to the release of some serotonin
*'''[[Effect::Physical effect2]]'''
*'''[[Effect::Physical euphoria]]'''
*'''[[Effect::Physical effect3]]'''
*'''[[Effect::Vibrating vision]]''' - Especially during the come up or after high doses.
*'''[[Effect::Bodily control enhancement]]'''
}}
*'''[[Effect::Teeth grinding]]''' - Mild, during the come-up or after high doses.
{{effects/visual|
*'''[[Effect::Increased heart rate]]'''
If applicable, a brief paragraph summary of the substance's visual effects may be included here.
*'''[[Effect::Stamina intensification]]'''
*'''[[Effect::Increased libido]]'''
You may select visual effects to add below [[Subjective effect index#Visual effects|here]].
*'''[[Effect::Increased blood pressure]]'''
*'''[[Effect::Dehydration]]'''
====Enhancements====
*'''[[Effect::Visual acuity effect1]]'''
====Distortions====
*'''[[Effect::Visual distortion effect1]]'''
====[[Effect::Geometry]]====
If applicable, a brief paragraph summary describing the visual geometry produced by the substance may be included here.
====Hallucinatory states====
If applicable, a brief summary of the substance's visual effects profile may be written here.
*'''[[Effect::Hallucinatory states1]]'''
}}
}}
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You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
*'''[[Effect::Cognitive effect1]]'''
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Cognitive effect2]]'''
*'''[[Effect::Cognitive euphoria]]'''
*'''[[Effect::Cognitive effect3]]'''
*'''[[Effect::Anxiety suppression]]'''
*'''[[Effect::Empathy, affection, and sociability enhancement]]'''
}}
*'''[[Effect::Time distortion]]''' - Time is heavily compressed.
{{effects/auditory|
*'''[[Effect::Motivation enhancement]]'''
If applicable, a brief paragraph summary of the substance's auditory effects may be included here.
*'''[[Effect::Focus suppression]]''' - The euphoria and the nystagmus overpower the ability to focus.
*'''[[Effect::Wakefulness]]'''
You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].
*'''[[Effect::Personal meaning intensification]]''' - Confidence and feeling good about yourself are common
*'''[[Effect::Ego inflation]]'''
*'''[[Effect::Auditory effect1]]'''
*'''[[Effect::Disinhibition]]'''
*'''[[Effect::Auditory effect2]]'''
*'''[[Effect::Thought organization]]'''
}}
}}
{{effects/multisensory|
If applicable, a brief paragraph summary of the substance's multisensory effects may be included here.
You may select from a list of multisensory effects to add below [[Subjective effect index#Multisensory effects|here]].
*'''[[Effect::Multisensory effect1]]'''
*'''[[Effect::Multisensory effect2]]'''
}}
}}
{{effects/transpersonal|
If applicable, a brief paragraph summary of the substance's transpersonal effects may be included here.
You may select from a list of transpersonal effects to add below [[Subjective effect index#Transpersonal effects|here]].
==Dangerous interactions==
*'''[[Effect::Transpersonal effect1]]'''
*'''[[Effect::Transpersonal effect2]]'''
}}
}}
===Experience reports===
There are currently {{#ask:[[Category:SUBSTANCE]][[Category:Experience]] | format=count}} experience reports which describe the effects of this substance in our [[experience index]].
* [https://www.erowid.org/experiences/subs/exp_SUBSTANCE.shtml Erowid Experience Vaults: SUBSTANCE] <!-- Check the link to see if it exists -->
==Toxicity and harm potential==
{{toxicity}}
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
===Lethal dosage===
===Tolerance and addiction potential===
===Dangerous interactions===
{{DangerousInteractions}}
{{DangerousInteractions}}
{{DangerousInteractions/Intro}}
{{DangerousInteractions/Intro}}
{{DangerousInteractions/Amphetamines}}
==Legal status==
==Legal status==
{{LegalStub}}
*'''France''': As of december 2024, 3-MMA is not explicitly scheduled. It is thus legal to possess, although in a grey area.<ref>{{Citation | title=Arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants | url=https://www.legifrance.gouv.fr/loda/id/JORFTEXT000000533085/2020-11-20/}}</ref>
3-Methylmethamphetamine (3-MMA) or Metaphedrine is an amphetamine derivative which has been sold as a designer drug, first being reported in Sweden in 2021.
3-MMA is the β-deketo analogue of 3MMC.
3-MMA exerts its effects by increasing the signaling activity of neurotransmitters norepinephrine, dopamine and to a lesser degree serotonin. [[User:AufderheideblühteinkleinesBlümelein|AufderheideblühteinkleinesBlümelein]] ([[User talk:AufderheideblühteinkleinesBlümelein|talk]]) 17:31, 19 December 2024 (UTC)
It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.
DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
3-MMA (also known as '3,N-Dimethylamphetamine, Emma, 3-Me-Ma or 3-Methyl-Methamphetamine) is a stimulant substance of the amphetamine class. It was first synthesized 2020 by a research chemical vendor called "Juklis Lab"[1][citation needed]
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
Physical effects
If applicable, a brief paragraph summary of the substance's physical effects may be included here.
You may select physical effects to add below here.
Stimulation - sort of a warm stimulation due to the release of some serotonin
If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.
You may select from a list of cognitive effects to add below here.
Warning:Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).
Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.
Alcohol - Drinking alcohol on stimulants is considered risky because it reduces the sedative effects of the alcohol that the body uses to gauge drunkenness. This often leads to excessive drinking with greatly reduced inhibitions, increasing the risk of liver damage and increased dehydration. The effects of stimulants will also allow one to drink past a point where they might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol and the stimulant less.
GHB/GBL - Stimulants increase respiration rate allowing a higher dose of sedatives. If the stimulant wears off first then the depressant effects of the GHB/GBL may overcome the user and cause respiratory arrest.
Opioids - Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.
Cocaine - The rewarding effects of cocaine are mediated by DAT inhibition, and an increase of exocytosis of dopamine through the cell membrane. Amphetamine reverses the direction of DAT and the direction vesicular transports within the cell by a pH mediated mechanism of displacement, thus excludes the regular mechanism of dopamine release through means of exocytosis because the effects Na+/K+ ATPase are inhibited. You will find cardiac effects with the combination of cocaine and amphetamine due to a SERT mediated mechanism from the subsequent activation of 5-HT2B, which is an effect of serotonin-related valvulopathy. Amphetamines generally cause hypertension in models of abuse, and this combination can increase the chances of syncope due to turbulent blood flow during valve operation. The rewarding mechanisms of cocaine are reversed by administration of amphetamine.[2][3]
Cannabis - Stimulants increase anxiety levels and the risk of thought loops and paranoia which can lead to negative experiences.
Caffeine - This combination of stimulants is generally considered unnecessary and may increase strain on the heart, as well as potentially causing anxiety and physical discomfort.
Tramadol - Tramadol and stimulants both increase the risk of seizures.
DXM - Both substances raise heart rate, in extreme cases, panic attacks caused by these substances have led to more serious heart issues.
Ketamine - Combining amphetamine and ketamine may result in psychoses that resemble schizophrenia, but not worse than the psychoses produced by either substance alone, but this is debatable. This is due to amphetamines ability to attenuated the disruption of working memory caused by ketamine. Amphetamine alone may result in grandiosity, paranoia, or somatic delusions with little to no effect on negative symptoms. Ketamine, however, will result in thought disorders, disruption of executive functioning, and delusions due to a modification of conception. These mechanisms are due to an increase of dopaminergic activity in the mesolimbic pathway caused by amphetamine due to its pharmacology effecting dopamine, and due to a disruption of dopaminergic functioning in the mesocortical pathways via NMDA antagonism effects of ketamine. Combining the two, you may expect mainly thought disorder along with positive symptoms.[4]
PCP - Increases risk of tachycardia, hypertension, and manic states.
Methoxetamine - Increases risk of tachycardia, hypertension, and manic states.
25x-NBOMe - Amphetamines and NBOMes both provide considerable stimulation that when combined they can result in tachycardia, hypertension, vasoconstriction and, in extreme cases, heart failure. The anxiogenic and focusing effects of stimulants are also not good in combination with psychedelics as they can lead to unpleasant thought loops. NBOMes are known to cause seizures and stimulants can increase this risk.
2C-T-x - Suspected of mild MAOI properties. May increase the risk of hypertensive crisis.
5-MeO-xxT - Suspected of mild MAOI properties. May increase the risk of hypertensive crisis.
DOx
aMT - aMT has MAOI properties which may interact unfavorably with amphetamines.
MAOIs - MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably. MAO-A inhibitors with amphetamine can lead to hypertensive crises.
Legal status
France: As of december 2024, 3-MMA is not explicitly scheduled. It is thus legal to possess, although in a grey area.[5]
3-Methylmethamphetamine (3-MMA) or Metaphedrine is an amphetamine derivative which has been sold as a designer drug, first being reported in Sweden in 2021.
3-MMA is the β-deketo analogue of 3MMC.
3-MMA exerts its effects by increasing the signaling activity of neurotransmitters norepinephrine, dopamine and to a lesser degree serotonin. AufderheideblühteinkleinesBlümelein (talk) 17:31, 19 December 2024 (UTC)
