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2C-T-x: Difference between revisions

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>David Hedlund
===Dangerous interactions=== {{DangerousInteractions/Intro}} {{DangerousInteractions/2C-T-x}}
>Snowcyclone
m Changed from R5 to RS for substitution. R5 would be a ring-substitute, RS is a substitution on the sulphur-atom of the molecule.
 
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[[File:2C-T.png|250px|thumbnail|The general structure for a 2C-T-x compound]]
[[File:Substituted 2C-T-x.svg|250px|thumbnail|The general structure for a 2C-T-x compound]]


'''2C-T-x''' is a subset of the [[2C-x]] series. [[Alexander Shulgin]] has discovered over 25 2C-T-x compounds and more are currently being made by individual scientists such as Daniel Trachsel<ref>https://onlinelibrary.wiley.com/doi/abs/10.1002/hlca.200390210</ref>.<ref>http://countyourculture.com/2011/01/15/shulgins-sulfur-symphony-part-i/</ref>
'''2C-T-x''' is a subset of the [[2C-x]] series. [[Alexander Shulgin]] has discovered over 25 2C-T-x compounds and more are currently being made by individual scientists such as Daniel Trachsel<ref>{{cite journal | vauthors=((Trachsel, D.)) | journal=Helvetica Chimica Acta | title=Synthese von neuen (Phenylalkyl)aminen zur Untersuchung von Struktur–Aktivitätsbeziehungen. Mitteilung 2: 4-Thio-substituierte[2-(2,5-Dimethoxyphenyl)ethyl]amine (=2,5-Dimethoxybenzolethanamine) | volume=86 | issue=7 | pages=2610–2619 | date= July 2003 | url=https://onlinelibrary.wiley.com/doi/10.1002/hlca.200390210 | issn=0018-019X | doi=10.1002/hlca.200390210}}</ref>.<ref>http://countyourculture.com/2011/01/15/shulgins-sulfur-symphony-part-i/</ref>


The 2C-T-x series contains a very broad spectrum of compounds from barely active to fully psychedelic phenethylamines. It is theorized that all of the members are [[MAOI]]s, as it is seen within the [[ALEPH]] series{{citation needed}}. Many have not been synthesized yet.
The 2C-T-x series contains a very broad spectrum of compounds from barely active to fully psychedelic phenethylamines. It is theorized that all of the members are [[MAOI]]s, as it is seen within the [[ALEPH]] series{{citation needed}}. Many have not been synthesized yet.


Among the members, the most popular ones are [[2C-T-2]] and [[2C-T-7]], which are part of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine compounds, all of which -- with the exception of [[mescaline]] -- he designed, synthesized and tested on himself. They can be found within the first book of PiHKAL, and are as follows: [[Mescaline]], [[DOM]], [[2C-B]], [[2C-E]], [[2C-T-2]] and [[2C-T-7]].<ref>https://erowid.org/library/books_online/pihkal/pihkal.shtml | [[PiHKAL]] </ref>
Among the members, the most popular ones are [[2C-T-2]] and [[2C-T-7]], which are part of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine compounds, all of which -- with the exception of [[mescaline]] -- he designed, synthesized and tested on himself. They can be found within the first book of PiHKAL, and are as follows: [[Mescaline]], [[DOM]], [[2C-B]], [[2C-E]], [[2C-T-2]] and [[2C-T-7]].<ref>{{Citation | title=Erowid Online Books : “PIHKAL” - The Chemical Story | url=https://erowid.org/library/books_online/pihkal/pihkal.shtml}}</ref>


==List of 2C-T-x compunds==
==List of 2C-T-x compunds==
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|-
|-
! scope="col" |'''Compound'''
! scope="col" |'''Compound'''
! scope="col" style="width: 50px;" |'''R<sub>4</sub>'''
! scope="col" style="width: 50px;" |'''R<sub>S</sub>'''
! scope="col" |'''Structure'''
! scope="col" |'''Structure'''
|-
|-
|2C-T<!-- general structure for a 2C-T-x compound -->||SCH<sub>3</sub>||[[File:2C-T.svg|140px]]
|[[2C-T]]||CH<sub>3</sub>||[[File:2C-T.svg|140px]]
|-
|-
|[[2C-T-2]]||SCH<sub>2</sub>CH<sub>3</sub>||[[File:2C-T-2.svg|140px]]
|[[2C-T-2]]||CH<sub>2</sub>CH<sub>3</sub>||[[File:2C-T-2.svg|140px]]
|-
|-
|2C-T-3 (2C-T-20)||SCH<sub>2</sub>||[[File:2C-T-3 or 2C-T-20.svg|140px]]
|2C-T-3 (2C-T-20)||CH<sub>2</sub>C(CH<sub>2</sub>)CH<sub>3</sub>||[[File:2C-T-3.svg|140px]]
|-
|-
|2C-T-4||SCH(CH<sub>3</sub>)<sub>2</sub>||[[File:2C-T-4.svg|140px]]
|2C-T-4||CH(CH<sub>3</sub>)<sub>2</sub>||[[File:2C-T-4.svg|140px]]
|-
|-
|2C-T-5||SCH<sub>2</sub>||[[File:2C-T-5.svg|140px]]
|2C-T-5||C<sub>6</sub>H<sub>11</sub>||[[File:2C-T-5.svg|140px]]
|-
|-
|2C-T-6||SCH<sub>2</sub>||[[File:2C-T-6.svg|140px]]
|2C-T-6||C<sub>6</sub>H<sub>5</sub>||[[File:2C-T-6.svg|140px]]
|-
|-
|[[2C-T-7]]||SCH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub>||[[File:2C-T-7.svg|140px]]
|[[2C-T-7]]||CH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub>||[[File:2C-T-7.svg|140px]]
|-
|-
|2C-T-8||SCH<sub>2</sub>||[[File:2C-T-8.svg|140px]]
|2C-T-8||CH<sub>2</sub>C<sub>3</sub>H<sub>5</sub>||[[File:2C-T-8.svg|140px]]
|-
|-
|2C-T-9||SCH<sub>2</sub>||[[File:2C-T-9.svg|140px]]
|2C-T-9||C(CH<sub>3</sub>)<sub>3</sub>||[[File:2C-T-9.svg|140px]]
|-
|-
|2C-T-10||SCH<sub>2</sub>||[[File:2C-T-10.svg|140px]]
|2C-T-10||C<sub>5</sub>H<sub>4</sub>N||[[File:2C-T-10.svg|140px]]
|-
|-
|2C-T-11||SCH<sub>2</sub>||[[File:2C-T-11.svg|140px]]
|2C-T-11||C<sub>6</sub>H<sub>4</sub>Br||[[File:2C-T-11.svg|140px]]
|-
|-
|2C-T-12||SCH<sub>2</sub>||[[File:2C-T-12.svg|140px]]
|2C-T-12||NC<sub>4</sub>H<sub>8</sub>O||[[File:2C-T-12.svg|140px]]
|-
|-
|2C-T-13||SCH<sub>2</sub>||[[File:2C-T-13.svg|140px]]
|2C-T-13||CH<sub>2</sub>CH<sub>2</sub>OCH<sub>3</sub>||[[File:2C-T-13.svg|140px]]
|-
|-
|2C-T-14||SCH<sub>2</sub>||[[File:2C-T-14.svg|140px]]
|2C-T-14||CH<sub>2</sub>CH<sub>2</sub>SCH<sub>3</sub>||[[File:2C-T-14.svg|140px]]
|-
|-
|2C-T-15||SCH<sub>2</sub>||[[File:2C-T-15 or SESQUI.svg|140px]]
|2C-T-15||C<sub>3</sub>H<sub>5</sub>||[[File:2C-T-15.svg|140px]]
|-
|-
|2C-T-16||SCH<sub>2</sub>||[[File:2C-T-16.svg|140px]]
|2C-T-16||CH<sub>2</sub>CH=CH<sub>2</sub>||[[File:2C-T-16.svg|140px]]
|-
|-
|2C-T-17||SCH<sub>2</sub>||[[File:2C-T-17 or NIMITZ.svg|140px]]
|2C-T-17||CH(CH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub>||[[File:2C-T-17.svg|140px]]
|-
|-
|2C-T-18||SCH<sub>2</sub>||[[File:2C-T-18.svg|140px]]
|2C-T-18||C<sub>4</sub>H<sub>7</sub>||[[File:2C-T-18.svg|140px]]
|-
|-
|}
|}
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|-
|-
! scope="col" |'''Compound'''
! scope="col" |'''Compound'''
! scope="col" style="width: 50px;" |'''R<sub>4</sub>'''
! scope="col" style="width: 50px;" |'''R<sub>S</sub>'''
! scope="col" |'''Structure'''
! scope="col" |'''Structure'''
|-
|-
|2C-T-19||SCH<sub>2</sub>||[[File:2C-T-19.svg|140px]]
|2C-T-19||CH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub>||[[File:2C-T-19.svg|140px]]
|-
|-
|2C-T-20 (2C-T-3)||SCH<sub>2</sub>||[[File:2C-T-3 or 2C-T-20.svg|140px]]
|[[2C-T-21]]||CH<sub>2</sub>CH<sub>2</sub>F||[[File:2C-T-21.svg|140px]]
|-
|-
|[[2C-T-21]]||SCH<sub>2</sub>CH<sub>2</sub>||[[File:2C-T-21.svg|140px]]
|2C-T-21.5||CH<sub>2</sub>CHF<sub>2</sub>||[[File:2C-T-21.5.svg|140px]]
|-
|-
|2C-T-21.5||SCH<sub>2</sub>CH<sub>2</sub>||[[File:2C-T-21.5.svg|140px]]
|2C-T-22||CH<sub>2</sub>CF<sub>3</sub>||[[File:2C-T-22.svg|140px]]
|-
|-
|2C-T-22||SCH<sub>2</sub>||[[File:2C-T-22.svg|140px]]
|2C-T-23||C<sub>5</sub>H<sub>9</sub>||[[File:2C-T-23.svg|140px]]
|-
|-
|2C-T-23||SCH<sub>2</sub>||[[File:2C-T-23.svg|140px]]
|2C-T-24||N(CH<sub>2</sub>CH<sub>3</sub>)<sub>2</sub>||[[File:2C-T-24.svg|140px]]
|-
|-
|2C-T-24||SCH<sub>2</sub>||[[File:2C-T-24.svg|140px]]
|2C-T-25||CH<sub>2</sub>CH(CH<sub>3</sub>)<sub>2</sub>||[[File:2C-T-25.svg|140px]]
|-
|-
|2C-T-25||SCH<sub>2</sub>||[[File:2C-T-25.svg|140px]]
|2C-T-26||CH(CH<sub>2</sub>F)<sub>2</sub>||[[File:2C-T-26.svg|140px]]
|-
|-
|2C-T-26||SCH<sub>2</sub>||[[File:2C-T-26.svg|140px]]
|2C-T-27||CH<sub>2</sub>C<sub>6</sub>H<sub>5</sub>||[[File:2C-T-27.svg|140px]]
|-
|-
|2C-T-27||SCH<sub>2</sub>||[[File:2C-T-27.svg|140px]]
|2C-T-28||CH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>F||[[File:2C-T-28.svg|140px]]
|-
|-
|2C-T-28||SCH<sub>2</sub>||[[File:2C-T-28.svg|140px]]
|2C-T-29||CH<sub>2</sub>C≡CH||[[File:2C-T-29.svg|140px]]
|-
|-
|2C-T-29||SCH<sub>2</sub>||[[File:2C-T-29.svg|140px]]
|2C-T-30||CH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>F||[[File:2C-T-30.svg|140px]]
|-
|-
|2C-T-30||SCH<sub>2</sub>||[[File:2C-T-30.svg|140px]]
|2C-T-31||CH<sub>2</sub>C<sub>6</sub>H<sub>4</sub>CF<sub>3</sub>||[[File:2C-T-31.svg|140px]]
|-
|-
|2C-T-31||SCH<sub>2</sub>||[[File:2C-T-31.svg|140px]]
|2C-T-32||CH<sub>2</sub>C<sub>6</sub>F<sub>5</sub>||[[File:2C-T-32.svg|140px]]
|-
|-
|2C-T-32||SCH<sub>2</sub>||[[File:2C-T-32.svg|140px]]
|2C-T-33||CH<sub>2</sub>C<sub>6</sub>H<sub>4</sub>OCH<sub>3</sub>||[[File:2C-T-33.svg|140px]]
|-
|-
|2C-T-33||SCH<sub>2</sub>||[[File:2C-T-33.svg|140px]]
|2C-T-34||CH<sub>2</sub>F||[[File:2C-T-34.svg|140px]]
|-
|-
|2C-T-34||SCH<sub>2</sub>||[[File:2C-T-34.svg|140px]]
|2C-T-35||CHF<sub>2</sub>||[[File:2C-T-35.svg|140px]]
|-
|-
|2C-T-35||SCH<sub>2</sub>||[[File:2C-T-35.svg|140px]]
|2C-T-36||CF<sub>3</sub>||[[File:2C-T-36.svg|140px]]
|-
|2C-T-36||SCH<sub>2</sub>||[[File:2C-T-36.svg|140px]]
|-
|-
|}
|}
|}
|}


==Health effects, potential addiction and tolerance==
==Toxicity and harm potential==
The 2C-x chemicals, as with many other serotonergic psychedelics, should not be taken in combination with SSRIs (selective [[serotonin]] [[reuptake Inhibitor]]) or [[tricyclic antidepressants]] in general to avoid [[Serotonin Syndrome]], a potentially life-threatening condition in which an abundance of serotonin is built up the body, causing many physical and cognitive health problems.
The 2C-T-x chemicals, as with many other serotonergic psychedelics, should not be taken in combination with SSRIs (selective [[serotonin]] [[reuptake Inhibitor]]) or [[tricyclic antidepressants]] in general to avoid [[serotonin syndrome]], a potentially life-threatening condition in which an abundance of serotonin is built up the body, causing many physical and cognitive health problems.
 
===Dangerous interactions===
{{DangerousInteractions/Intro}}
{{DangerousInteractions/2C-T-x}}


==See also==
==See also==
Line 125: Line 119:
==References==
==References==
<references />
<references />
[[Category:Chemical class]]
[[Category:2C-T-x|*]]

Latest revision as of 10:16, 3 March 2024

This article is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

The general structure for a 2C-T-x compound

2C-T-x is a subset of the 2C-x series. Alexander Shulgin has discovered over 25 2C-T-x compounds and more are currently being made by individual scientists such as Daniel Trachsel[1].[2]

The 2C-T-x series contains a very broad spectrum of compounds from barely active to fully psychedelic phenethylamines. It is theorized that all of the members are MAOIs, as it is seen within the ALEPH series[citation needed]. Many have not been synthesized yet.

Among the members, the most popular ones are 2C-T-2 and 2C-T-7, which are part of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine compounds, all of which -- with the exception of mescaline -- he designed, synthesized and tested on himself. They can be found within the first book of PiHKAL, and are as follows: Mescaline, DOM, 2C-B, 2C-E, 2C-T-2 and 2C-T-7.[3]

List of 2C-T-x compunds

Compound RS Structure
2C-T CH3
2C-T-2 CH2CH3
2C-T-3 (2C-T-20) CH2C(CH2)CH3
2C-T-4 CH(CH3)2
2C-T-5 C6H11
2C-T-6 C6H5
2C-T-7 CH2CH2CH3
2C-T-8 CH2C3H5
2C-T-9 C(CH3)3
2C-T-10 C5H4N
2C-T-11 C6H4Br
2C-T-12 NC4H8O
2C-T-13 CH2CH2OCH3
2C-T-14 CH2CH2SCH3
2C-T-15 C3H5
2C-T-16 CH2CH=CH2
2C-T-17 CH(CH3)CH2CH3
2C-T-18 C4H7
Compound RS Structure
2C-T-19 CH2CH2CH2CH3
2C-T-21 CH2CH2F
2C-T-21.5 CH2CHF2
2C-T-22 CH2CF3
2C-T-23 C5H9
2C-T-24 N(CH2CH3)2
2C-T-25 CH2CH(CH3)2
2C-T-26 CH(CH2F)2
2C-T-27 CH2C6H5
2C-T-28 CH2CH2CH2F
2C-T-29 CH2C≡CH
2C-T-30 CH2CH2CH2CH2F
2C-T-31 CH2C6H4CF3
2C-T-32 CH2C6F5
2C-T-33 CH2C6H4OCH3
2C-T-34 CH2F
2C-T-35 CHF2
2C-T-36 CF3

Toxicity and harm potential

The 2C-T-x chemicals, as with many other serotonergic psychedelics, should not be taken in combination with SSRIs (selective serotonin reuptake Inhibitor) or tricyclic antidepressants in general to avoid serotonin syndrome, a potentially life-threatening condition in which an abundance of serotonin is built up the body, causing many physical and cognitive health problems.

See also

References

  1. ↑ Trachsel, D. (July 2003). "Synthese von neuen (Phenylalkyl)aminen zur Untersuchung von Struktur–Aktivitätsbeziehungen. Mitteilung 2: 4-Thio-substituierte[2-(2,5-Dimethoxyphenyl)ethyl]amine (=2,5-Dimethoxybenzolethanamine)". Helvetica Chimica Acta. 86 (7): 2610–2619. doi:10.1002/hlca.200390210. ISSN 0018-019X. 
  2. ↑ http://countyourculture.com/2011/01/15/shulgins-sulfur-symphony-part-i/
  3. ↑ Erowid Online Books : “PIHKAL” - The Chemical Story 
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