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Substituted piperazines: Difference between revisions
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[[File:Piperazine.svg|thumb|right|100px||The structure of the piperazine molecule]] | [[File:Piperazine.svg|thumb|right|100px||The structure of the piperazine molecule]] | ||
'''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects. They can be divided into two classes, the benzylpiperazines such as [[BZP]] itself, and its methylenedioxy analogue [[MDBZP]], and the phenylpiperazines [[mCPP]], [[TFMPP]], and [[MeOPP]]. | '''Substituted piperazines''' refers to a class of chemicals that typically have [[stimulant]] effects. They can be divided into two classes, the benzylpiperazines such as [[BZP]] itself, and its methylenedioxy analogue [[MDBZP]], and the phenylpiperazines [[mCPP]], [[TFMPP]], and [[MeOPP]]. Some deaths have rarely occurred when consuming BZP, it can increase chances of having seizures. | ||
==Chemistry== | ==Chemistry== | ||
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Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring. | Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R<sub>1</sub> and R<sub>4</sub> of the ring. | ||
==Recreational Piperazines== | <div class="flex-panel"> | ||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Recreational Piperazines</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[2C-B-BZP]] | *[[2C-B-BZP]] | ||
*[[3C-PEP]] | |||
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'') | |||
*[[BZP]] (''Benzylpiperazine'') | *[[BZP]] (''Benzylpiperazine'') | ||
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'') | *[[DCPP]] (''2,3-Dichlorophenylpiperazine'') | ||
*[[DBZP]] (''1,4-Dibenzylpiperazine'') | *[[DBZP]] (''1,4-Dibenzylpiperazine'') | ||
*[[MBZP]] (''4-Methyl-1-benzylpiperazine'') | *[[MBZP]] (''4-Methyl-1-benzylpiperazine'') | ||
*[[MDBZP]] (''Methylenedioxybenzylpiperazine'') | |||
*[[mCPP]] (''3-Chlorophenylpiperazine'') | *[[mCPP]] (''3-Chlorophenylpiperazine'') | ||
*[[MDBZP]] (''3,4-Methylenedioxy-1-benzylpiperazine'') | *[[MDBZP]] (''3,4-Methylenedioxy-1-benzylpiperazine'') | ||
*[[MeOP]] (''Methoxypiperamide'') | |||
*[[MeOPP]] (''para-methoxyphenylpiperazine'') | *[[MeOPP]] (''para-methoxyphenylpiperazine'') | ||
*[[MT-45]] (''1-cyclohexyl-4-(1,2-diphenylethyl)piperazine'') | *[[MT-45]] (''1-cyclohexyl-4-(1,2-diphenylethyl)piperazine'') | ||
*[[mTFMPP]] | *[[mTFMPP]] | ||
*[[oCPP]] (''2-Chlorophenylpiperazine'') | |||
*[[oMPP]] (''2-Methylphenylpiperazine'') | |||
*[[oMeOPP]] (''2-Methoxyphenylpiperazine'') | |||
*[[oTFMPP]] | *[[oTFMPP]] | ||
*[[pCPP]] (''4-Chlorophenylpiperazine'') | *[[pCPP]] (''4-Chlorophenylpiperazine'') | ||
| Line 23: | Line 36: | ||
*[[pTFMPP]] | *[[pTFMPP]] | ||
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'') | *[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'') | ||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Benzylpiperazines</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[2C-B-BZP]] | |||
*[[3-Me-BZP]] (''3-Methylbenzylpiperazine'') | |||
*[[Befuraline]] | |||
*[[Bifeprunox]] | |||
*[[Buclizine]] | |||
*[[BZP]] (''Benzylpiperazine'') | |||
*[[Chlorbenzoxamine]] | |||
*[[DBZP]] | |||
*[[DF-MDBP]] (''Difluoromethylenedioxybenzylpiperazine'') | |||
*[[Fipexide]] | |||
*[[Imatinib]] | |||
*[[MBZP]] | |||
*[[MDBZP]] | |||
*[[Meclozine]] | |||
*[[MeOP]] (''Methoxypiperamide'') | |||
*[[Piberaline]] | |||
*[[Piribedil]] | |||
*[[RN-1747]] | |||
*[[Sunifiram]] | |||
*[[Trimetazidine]] | |||
*[[TFMCPP]] (''3-Trifluoromethyl-4-chlorophenylpiperazine'') | |||
*[[Vesnarinone]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Phenylpiperazines</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[2C-B-PP]] (''2,5-dimethoxy-4-bromophenylpiperazine'') | |||
*[[3,4-CFP]] (''3-Chloro-4-fluorophenylpiperazine'') | |||
*[[3C-PEP]] | |||
*[[Acaprazine]] | |||
*[[Aripiprazole]] (''Abilify'') | |||
*[[Bifeprunox]] | |||
*[[Brexpiprazole]] | |||
*[[Cariprazine]] | |||
*[[DCPP]] (''2,3-Dichlorophenylpiperazine'') | |||
*[[Elopiprazole]] | |||
*[[Enciprazine]] | |||
*[[Enpiprazole]] | |||
*[[Ensaculin]] | |||
*[[Etoperidone]] | |||
*[[Flesinoxan]] | |||
*[[Lorpiprazole]] | |||
*[[Mepiprazole]] | |||
*[[mCPP]] (''3-Chlorophenylpiperazine'') | |||
*[[mMeOPP]] (''3-Methoxyphenylpiperazine'') | |||
*[[Naluzotan]] | |||
*[[Naphthylpiperazine]] | |||
*[[Nefazodone]] | |||
*[[TFMPP]] (''3-Trifluoromethylphenylpiperazine'') | |||
*[[Tolpiprazole]] | |||
*[[Trazodone]] | |||
*[[Vilazodone]] | |||
*[[Vortioxetine]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Pyrimidinylpiperazine</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[Buspirone]] | |||
*[[Dasatinib]] | |||
*[[Eptapirone]] | |||
*[[Gepirone]] | |||
*[[Ipsapirone]] | |||
*[[Piribedil]] | |||
*[[Quipazine]] | |||
*[[Revospirone]] | |||
*[[Tandospirone]] | |||
*[[Tirilazad]] | |||
*[[Umespirone]] | |||
*[[Zalospirone]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Pyridinylpiperazine</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[Azaperone]] | |||
*[[Atevirdine]] | |||
*[[Delavirdine]] | |||
*[[Mirtazapine]] | |||
*[[ORG-12962]] | |||
*[[ORG-37684]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
</div> | |||
<div class="flex-column"> | |||
<div class="panel radius"> | |||
<h3 class="panel-header">Other</h3> | |||
<ul class="featured-table"> | |||
<li class="featured list-item"> | |||
*[[AD-1211]] | |||
*[[AP-238]] | |||
*[[Azaprocin]] | |||
*[[Buclizine]] | |||
*[[Bucinnazine]] (''AP-237'') | |||
*[[Cetirizine]] (''Zyrtec'') | |||
*[[Chlorcyclizine]] | |||
*[[Cinnarizine]] | |||
*[[Cyclizine]] | |||
*[[Diphenpipenol]] | |||
*[[Etodroxizine]] | |||
*[[Flunarizine]] | |||
*[[Homochlorcyclizine]] | |||
*[[Hydroxyzine]] | |||
*[[Meclizine]] | |||
*[[MT-45]] (''IC-6'') | |||
*[[NSI-189]] | |||
*[[Oxatomide]] | |||
*[[Perospirone]] | |||
*[[Pipoxizine]] | |||
*[[Tiospirone]] | |||
*[[Unifiram]] | |||
</li> | |||
</ul> | |||
</div> | |||
</div> | |||
</div> | |||
==Pharmacology== | ==Pharmacology== | ||
Latest revision as of 10:10, 24 May 2022
 |
This article is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it. |
Substituted piperazines refers to a class of chemicals that typically have stimulant effects. They can be divided into two classes, the benzylpiperazines such as BZP itself, and its methylenedioxy analogue MDBZP, and the phenylpiperazines mCPP, TFMPP, and MeOPP. Some deaths have rarely occurred when consuming BZP, it can increase chances of having seizures.
Chemistry
 |
This chemistry section is incomplete. You can help by adding to it. |
Piperazine is a cyclohexane-based structure that contains two nitrogen atoms at R1 and R4 of the ring.
Recreational Piperazines
-
- 2C-B-BZP
- 3C-PEP
- 3-Me-BZP (3-Methylbenzylpiperazine)
- BZP (Benzylpiperazine)
- DCPP (2,3-Dichlorophenylpiperazine)
- DBZP (1,4-Dibenzylpiperazine)
- MBZP (4-Methyl-1-benzylpiperazine)
- MDBZP (Methylenedioxybenzylpiperazine)
- mCPP (3-Chlorophenylpiperazine)
- MDBZP (3,4-Methylenedioxy-1-benzylpiperazine)
- MeOP (Methoxypiperamide)
- MeOPP (para-methoxyphenylpiperazine)
- MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine)
- mTFMPP
- oCPP (2-Chlorophenylpiperazine)
- oMPP (2-Methylphenylpiperazine)
- oMeOPP (2-Methoxyphenylpiperazine)
- oTFMPP
- pCPP (4-Chlorophenylpiperazine)
- pFPP (4-Fluorophenylpiperazine)
- pTFMPP
- TFMPP (3-Trifluoromethylphenylpiperazine)
Benzylpiperazines
-
- 2C-B-BZP
- 3-Me-BZP (3-Methylbenzylpiperazine)
- Befuraline
- Bifeprunox
- Buclizine
- BZP (Benzylpiperazine)
- Chlorbenzoxamine
- DBZP
- DF-MDBP (Difluoromethylenedioxybenzylpiperazine)
- Fipexide
- Imatinib
- MBZP
- MDBZP
- Meclozine
- MeOP (Methoxypiperamide)
- Piberaline
- Piribedil
- RN-1747
- Sunifiram
- Trimetazidine
- TFMCPP (3-Trifluoromethyl-4-chlorophenylpiperazine)
- Vesnarinone
Phenylpiperazines
-
- 2C-B-PP (2,5-dimethoxy-4-bromophenylpiperazine)
- 3,4-CFP (3-Chloro-4-fluorophenylpiperazine)
- 3C-PEP
- Acaprazine
- Aripiprazole (Abilify)
- Bifeprunox
- Brexpiprazole
- Cariprazine
- DCPP (2,3-Dichlorophenylpiperazine)
- Elopiprazole
- Enciprazine
- Enpiprazole
- Ensaculin
- Etoperidone
- Flesinoxan
- Lorpiprazole
- Mepiprazole
- mCPP (3-Chlorophenylpiperazine)
- mMeOPP (3-Methoxyphenylpiperazine)
- Naluzotan
- Naphthylpiperazine
- Nefazodone
- TFMPP (3-Trifluoromethylphenylpiperazine)
- Tolpiprazole
- Trazodone
- Vilazodone
- Vortioxetine
Pyrimidinylpiperazine
Pyridinylpiperazine
Pharmacology
 |
This pharmacology section is incomplete. You can help by adding to it. |
Piperazines typically have stimulant effects.
See also
External links
- [Piperazine (Wikipedia)https://en.wikipedia.org/wiki/Piperazine]
- Substituted piperazine (Wikipedia)
- Piperazines (Erowid Vault)
References
 |
This article does not cite enough references. You can help by adding some. |