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'''Microdosing''' (a shortened form of '''psychedelic microdosing''') is the novel practice of using subthreshold doses of a psychedelic substance in order to enhance productivity, treat symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, and to boost one's creativity, abstract thought & problem-solving abilities in everyday life, as well as potentially increase spiritual awareness. However, it should be noted that at this time there is no scientific evidence to support these claims.
'''Microdosing''' (also known as '''psychedelic microdosing''') is the practice of using sub-threshold doses of a psychedelic substance in an attempt to produce a therapeutic or [[nootropic]] effect. Microdosing has been claimed by some to have a wide range of benefits including enhancing productivity, treating symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, boosting creativity and problem-solving abilities, as well as increase spiritual awareness. There is currently no clinical evidence to support these claims, however a number of small scale studies have shown positive outcomes. In 2020 a study by the Beckley Foundation found that a 20 microgram dose of LSD significantly reduced pain perception when compared to a placebo, with results comparable to those observed after administration of opioids.<ref>{{Cite web|url=https://www.leafie.co.uk/psychedelics/5-things-you-need-to-know-about-microdosing/|title=5 things you need to know about microdosing|website=leafie|access-date=16 September 2021}}</ref>
While it is possible to microdose with any [[psychedelic]] substance, the practice has its origins with [[LSD]]. Additionally, there is a growing body of reports of those who microdose with substances like [[psilocybin mushrooms]], or psychedelic [[research chemicals]], particularly with analogs of [[LSD]] such as [[ALD-52]], [[1P-LSD]], [[AL-LAD]] and [[ETH-LAD]].
While the practice has its origins with [[LSD]], it is in theory possible to microdose with any [[psychedelic]] substance. There are a growing body of reports of microdosing [[psilocybin mushrooms]], or psychedelic [[research chemicals]], particularly [[LSD]] analogs such as [[ALD-52]], [[1P-LSD]], [[AL-LAD]] and [[ETH-LAD]].
Generally, a microdose of LSD is considered to be between 5-20 micrograms (typically 10ug, +/-2ug) which can be measured very accurately using [[volumetric dosing]] techniques. A microdose of psilocybin mushrooms is a bit harder to determine due to the variations in potency between species and batches; so it is generally advised to start with no more than .25g.
Microdoses range from about one tenth of an active dose. A microdose of LSD is generally considered to be between 5-15 micrograms. This can be measured accurately using [[volumetric dosing]] techniques. A microdose of psilocybin mushrooms is harder to determine due to the variations in potency between species and batches; it is generally advised to start with no more than .25g.
==History and culture==
==Subjective effects==
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The panels below list the effects generally occur at a [[Dosage#Microdose|microdose]] dose for psychedelic substances according to reports by PsychonautWiki contributors.
*Horsley, R.R., Páleníček, T., Kolin, J., & Valeš, K. (2018). Psilocin and ketamine microdosing: effects of subchronic intermittent microdoses in the elevated plus-maze in male Wistar rats. Behavioural Pharmacology. https://doi.org/10.1097/FBP.0000000000000394
==References==
==References==
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[[Category:Approval]]
Latest revision as of 12:38, 25 September 2021
Microdosing (also known as psychedelic microdosing) is the practice of using sub-threshold doses of a psychedelic substance in an attempt to produce a therapeutic or nootropic effect. Microdosing has been claimed by some to have a wide range of benefits including enhancing productivity, treating symptoms of psychological disorders such as clinical depression and adult ADD/ADHD, boosting creativity and problem-solving abilities, as well as increase spiritual awareness. There is currently no clinical evidence to support these claims, however a number of small scale studies have shown positive outcomes. In 2020 a study by the Beckley Foundation found that a 20 microgram dose of LSD significantly reduced pain perception when compared to a placebo, with results comparable to those observed after administration of opioids.[1]
Microdoses range from about one tenth of an active dose. A microdose of LSD is generally considered to be between 5-15 micrograms. This can be measured accurately using volumetric dosing techniques. A microdose of psilocybin mushrooms is harder to determine due to the variations in potency between species and batches; it is generally advised to start with no more than .25g.
Horsley, R.R., Páleníček, T., Kolin, J., & Valeš, K. (2018). Psilocin and ketamine microdosing: effects of subchronic intermittent microdoses in the elevated plus-maze in male Wistar rats. Behavioural Pharmacology. https://doi.org/10.1097/FBP.0000000000000394
