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'''Physical fatigue''' (or '''muscle fatigue''') is the temporary physical inability of the muscles to perform optimally. It is a side effect characterized by feelings of tiredness and weakness. It can occur after prolonged physical exertion and extended periods of wakefulness. People who are fatigued may find it difficult to complete physical actions and may not be capable of getting out of bed or performing everyday household tasks. It can generally be treated with a period of rest or sleep.
'''Physical fatigue''' can be described as a general feeling of bodily exhaustion. The intensity and duration of this effect typically depends on the substance consumed and its dosage. It can also be further exacerbated by various factors such as a lack of sleep or food. These feelings of exhaustion involve a wide variety of symptoms which generally include some or all of the following effects:


[[Cognitive fatigue]], the mental equivalent of this component, frequently occurs simultaneously alongside of physical fatigue.
*'''[[Sedation]]'''
*'''[[Perception of bodily heaviness]]'''
*'''[[Decreased libido]]'''
*'''[[Motor control loss]]'''
*'''[[Sleepiness]]'''
 
People who are fatigued may find it difficult to complete physical actions and may not be capable of getting out of bed or performing everyday household tasks. It can generally be treated with a period of rest or sleep.
 
Physical fatigue is often accompanied by other coinciding effects such as [[cognitive fatigue]]. It is most commonly induced under the influence of [[dosage#common|moderate]] [[dosage|dosages]] of [[antipsychotic]] compounds, such as [[quetiapine]], [[haloperidol]], and [[risperidone]]. However, it can also occur during the [[withdrawal]] symptoms of many [[depressant|depressants]], and during the [[duration#offset|offset]] of many [[stimulant|stimulants]].
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===Psychoactive substances===
===Psychoactive substances===
Physical fatigue can occur as a withdrawal symptom of certain substances including [[opioids]], [[stimulant]]s, and [[alcohol]].
Compounds within our [[psychoactive substance index]] which may cause this effect include:
Compounds within our [[psychoactive substance index]] which may cause this effect include:
{{#ask:[[Category:Psychoactive substance]][[Effect::Physical fatigue]]|format=ul|Columns=1}}
{{#ask:[[Category:Psychoactive substance]][[Effect::Physical fatigue]]|format=ul|Columns=1}}
===Experience reports===
Annectdotal reports which describe this effect with our [[experience index]] include:
{{#ask:[[Category:Experience]][[Effect::Physical fatigue]]|format=ul|Columns=2}}
===See also===
===See also===
*[[Responsible use]]
*[[Responsible use]]
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*[[Dissociatives#Subjective_effects|Dissociatives - Subjective effects]]
*[[Dissociatives#Subjective_effects|Dissociatives - Subjective effects]]
*[[Deliriants#Subjective_effects|Deliriants - Subjective effects]]
*[[Deliriants#Subjective_effects|Deliriants - Subjective effects]]
[[Category:Physical]] [[Category:Uncomfortable]] [[Category:Effect]]
===External links===
* [https://en.wikipedia.org/wiki/Muscle_fatigue Muscle fatigue (Wikipedia)]
[[Category:Physical]][[Category:Uncomfortable]][[Category:Bodily]][[Category:Effect]]

Latest revision as of 13:33, 6 February 2020

Physical fatigue can be described as a general feeling of bodily exhaustion. The intensity and duration of this effect typically depends on the substance consumed and its dosage. It can also be further exacerbated by various factors such as a lack of sleep or food. These feelings of exhaustion involve a wide variety of symptoms which generally include some or all of the following effects:

People who are fatigued may find it difficult to complete physical actions and may not be capable of getting out of bed or performing everyday household tasks. It can generally be treated with a period of rest or sleep.

Physical fatigue is often accompanied by other coinciding effects such as cognitive fatigue. It is most commonly induced under the influence of moderate dosages of antipsychotic compounds, such as quetiapine, haloperidol, and risperidone. However, it can also occur during the withdrawal symptoms of many depressants, and during the offset of many stimulants.

Psychoactive substances

Compounds within our psychoactive substance index which may cause this effect include:

Experience reports

Annectdotal reports which describe this effect with our experience index include:

See also