Template:SubstanceBox/Pregabalin: Revision history

13 October 2022

• curprev 07:2607:26, 13 October 2022 >Isaak 5,943 bytes 0 Adjust the total such that it is the sum of onset, comeup, peak and offset for the min and max respectively.
• curprev 07:2207:22, 13 October 2022 >Isaak 5,943 bytes +111 According to the paper that is already linked peak plasma concentration after 300mg orally on an empty stomach occurs at 1h (+-21%) which means the onset + comeup must be at least 45-75min together. A breakfast in the study delayed it 2.8 hours. On an average full stomach we would add about 1.5 hours so the peak is reached at about 2.5 hours. Onset is not documented in the paper but for other substances oral onset is 30-45min. So that leaves 1-2 hours for the comeup.
• curprev 06:3806:38, 13 October 2022 >Isaak 5,832 bytes 0 Close gap between threshold and light dose
• curprev 06:3406:34, 13 October 2022 >Isaak 5,832 bytes +61 Annotate bioavailability correctly

27 July 2022

• curprev 17:5017:50, 27 July 2022 >Graham m 5,771 bytes +470 wiki ref formatting

12 May 2022

• curprev 20:2520:25, 12 May 2022 >Isaak 5,301 bytes +51 No edit summary

9 December 2021

• curprev 15:4115:41, 9 December 2021 >Nutmeg enjoyer 11 5,250 bytes +1,804 he dissociative effects of pregabalin that are described in the pregabalin article almost always appear in only higher doses as the old page was recommending, there are some hypersensitive people, fs, but 600 mg is a medical dosage and rarely will cause intense hallucinations. The dosage was perfect and had stayed the same for 3 years. I added dosage for rectal administration , i calculated them by % in oral vs rectal based off other substances on psychonautwiki
• curprev 15:4015:40, 9 December 2021 >Wanterwhite 3,446 bytes −1,805 Nvm i got accses to my old account ill edit there, sorry for making history if this page a mess
• curprev 15:3115:31, 9 December 2021 >Wanterwhite 5,251 bytes −67 i forgot to add the timeline for rectal ROA
• curprev 15:2915:29, 9 December 2021 >Wanterwhite 5,318 bytes +1,872 The dissociative effects of pregabalin that are described in the pregabalin article almost always appear in only higher doses as the old page was recommending, there are some hypersensitive people, fs, but 600 mg is a medical dosage and rarely will cause intense hallucinations. The dosage was perfect and had stayed the same for 3 years. I added dosage for rectal administration , i calculated them by % in oral vs rectal based off other substances on psychonautwiki

28 October 2021

• curprev 20:0920:09, 28 October 2021 >Reddit-Drug-Advice 3,446 bytes 0 The previous dosage ranges for pregabalin were extremely high considering it's variability in effect, and is especially cavalier compared to dosage recommendations for gabapentin. Studies on dose equivalency generally center around a 5:1 gabapentin to pregabalin ratio. Many non-tolerant individuals are quite sensitive and can be extremely inebriated at even a 300mg dose. I personally know two people who had difficult and disorienting experiences on 300mg. I can provide citations in discussion

25 December 2019

• curprev 15:0115:01, 25 December 2019 >Tracer 3,446 bytes −5 Grammatics

1 June 2019

• curprev 21:4521:45, 1 June 2019 >LockPicker m 3,451 bytes +63 Added citaion

31 July 2018

• curprev 07:5307:53, 31 July 2018 >BronzeManul 3,388 bytes +277 Increased oral minimum total duration from 6 to 8 hours and added oral peak, offset, and after effects duration ranges.
• curprev 07:5007:50, 31 July 2018 >BronzeManul 3,111 bytes −2 Reduced oral minimum common dose and oral max light dose from 300mg to 225mg and reduced oral minimum light dose from 150mg to 75mg.

13 May 2018

• curprev 00:2800:28, 13 May 2018 >BronzeManul 3,113 bytes +1 Adjusted onset times based on personal experience and on multiple experience reports for the substance.

12 December 2017

• curprev 20:2720:27, 12 December 2017 >BronzeManul 3,112 bytes −89 Undo revision 117929 by Aleksandar8239 (talk) TripSit is not at all a reliable source and these values are inaccurate.
• curprev 12:1412:14, 12 December 2017 >Aleksandar8239 3,201 bytes +89 source: https://drugs.tripsit.me/pregabalin

17 November 2017

• curprev 17:3617:36, 17 November 2017 >Unity 3,112 bytes +55 Add class membership markup. Citation flag for Oral BA value.
• curprev 17:2817:28, 17 November 2017 >BronzeManul 3,057 bytes 0 Undo revision 114569 by Aleksandar8239 (talk) Unless sufficient evidence is provided supporting the threshold dosage reduction. Research into the substance supports the 50mg threshold.
• curprev 13:5513:55, 17 November 2017 >Aleksandar8239 3,057 bytes 0 reduced threshold dose

30 August 2017

• curprev 03:5003:50, 30 August 2017 >BronzeManul m 3,057 bytes −1 Replaced skeletal structure image with standardised svg image.

27 August 2017

• curprev 12:5512:55, 27 August 2017 >Corticosteroid m 3,058 bytes 0 Corticosteroid moved page Template:SubstanceBox/Lyrica to Template:SubstanceBox/Pregabalin: use common name

25 June 2017

• curprev 02:5302:53, 25 June 2017 >Unity 3,058 bytes −46 Capitalize chemical names. Remove 3D image.

16 May 2017

• curprev 22:3622:36, 16 May 2017 >BronzeManul m 3,104 bytes 0 Grammatics
• curprev 22:1022:10, 16 May 2017 >BronzeManul m 3,104 bytes +31 Grammatics
• curprev 22:0922:09, 16 May 2017 >BronzeManul m 3,073 bytes +116 Added psychoactive and chemical class listings and made minor edits to naming section.

19 February 2017

• curprev 02:5802:58, 19 February 2017 >Kenan m 2,957 bytes +44 Text replacement - "{{SubstanceBox <!-- Table Properties -->" to "{{SubstanceBox <!-- Special Parameters --> |displayClasses={{{displayClasses|}}}"

30 January 2017

• curprev 23:0623:06, 30 January 2017 >Sir Kibs m 2,913 bytes 0 Changed threshold dose to 50-150 from 75-150
• curprev 02:0202:02, 30 January 2017 >BronzeManul m 2,913 bytes 0 Changed image widths to 245px and 200px.

25 January 2017

• curprev 04:3004:30, 25 January 2017 >Kenan m 2,913 bytes −433 Text replacement - "'''WARNING:''' Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. <u>See responsible use section.</u><br> '''DISCLAIMER:''' PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy." to ""

15 January 2017

• curprev 20:3620:36, 15 January 2017 >Alfie 3,346 bytes −1 No edit summary

13 January 2017

• curprev 04:5704:57, 13 January 2017 >Unity m 3,347 bytes −1 Text replacement - "MolecularStructureCaption=The skeletal formula" to "MolecularStructureCaption=Molecular structure"

22 May 2016

• curprev 15:3915:39, 22 May 2016 >Kaylee m 3,348 bytes +6 Text replacement - "_Afterglow=" to "_Aftereffects="
• curprev 15:3515:35, 22 May 2016 >Kaylee m 3,342 bytes −6 Text replacement - "Aftereffects" to "Afterglow"
• curprev 15:3115:31, 22 May 2016 >Kaylee m 3,348 bytes +6 Text replacement - "Afterglow" to "Aftereffects"

4 May 2016

• curprev 18:3718:37, 4 May 2016 >Josikins 3,342 bytes 0 No edit summary

3 May 2016

• curprev 01:4801:48, 3 May 2016 >Josikins 3,342 bytes +62 No edit summary

11 April 2016

• curprev 18:3718:37, 11 April 2016 >Josikins m 3,280 bytes +10 Text replacement - "See responsible use section" to "See responsible use section"

6 April 2016

• curprev 15:3315:33, 6 April 2016 >Kaylee 3,270 bytes −6 No edit summary
• curprev 15:3315:33, 6 April 2016 >Kaylee 3,276 bytes −3 No edit summary

1 April 2016

• curprev 07:3507:35, 1 April 2016 >Oskykins m 3,279 bytes +56 Text replacement - "PW's dosage information is a summary of data gathered from users and resources. It is not a recommendation and should be verified with other sources for accuracy." to "PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy."

25 February 2016

• curprev 04:2704:27, 25 February 2016 >Josikins m 3,223 bytes 0 Text replacement - "'''WARNING:''' Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. <u>See responsible use section.</u><br> '''DISCLAIMER:''' PW's dosage information is a summary of data gathered from users and resources. It is NOT a recommendation and should be verified with other sources for accuracy." to "'''WARNING:''' Always start with lower doses due to differences between...

24 February 2016

• curprev 23:5623:56, 24 February 2016 >Josikins m 3,223 bytes 0 Text replacement - "'''WARNING:''' Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. <u>See responsible use section.</u><br> '''DISCLAIMER:''' PW's dosage information is a summary of data gathered from users and resources. It is not a recommendation and should be verified with other sources for accuracy." to "'''WARNING:''' Always start with lower doses due to differences between...

20 February 2016

• curprev 06:0606:06, 20 February 2016 >Oskykins m 3,223 bytes +512 Text replacement - "'''WARNING:''' Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity." to "'''WARNING:''' Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. <u>See responsible use section.</u><br> '''DISCLAIMER:''' PW's dosage information is a summary of data gathered from users and resources. It is not...

2 February 2016

• curprev 00:2200:22, 2 February 2016 >Rhz m 2,711 bytes −3 Text replacement - "(\|)([A-Za-z]+)ROA_Duration=(.*)onset" to "$1$2ROA_Onset=$3onset"

1 February 2016

• curprev 23:5523:55, 1 February 2016 >Rhz m 2,714 bytes +82 Text replacement - "(\|)([A-Za-z]+)ROA_Onset=([ ]*)([0-9.]+)([ -]+)([0-9.]+)([ ]*)([^ 0-9]+) " to "$1$2ROA_Duration=$2 min onset time::$4 - $2 max onset time::$6 $2 onset time units::$8 "
• curprev 23:4323:43, 1 February 2016 >Rhz m 2,632 bytes +77 Text replacement - "(\|)([A-Za-z]+)ROA_Duration=([ ]*)([0-9.]+)([ -]+)([0-9.]+)([ ]*)([^ 0-9]+) " to "$1$2ROA_Duration=Oral min total time::$4 - Oral max total time::$6 Oral total time units::$8 "

25 November 2015

• curprev 02:4202:42, 25 November 2015 >Rhz m 2,555 bytes +21 Text replacement - "OralROA_Heavy=([> ]*)([0-9.]+)[ ]*([muµ]?g)" to "OralROA_Heavy=$1Oral heavy dose::$2 $3"
• curprev 02:2802:28, 25 November 2015 >Rhz m 2,534 bytes +52 Text replacement - "OralROA_Strong=[ ]*([0-9.]+)[ -]+([0-9.]+)[ ]*([muµ]?g)" to "OralROA_Strong=Oral min strong dose::$1 - Oral max strong dose::$2 $3"