Talk:Yohimbine

This article is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it.

Summary sheet: Yohimbine

Yohimbine (also known as quebrachine) is a naturally-occurring stimulant substance derived from the bark of the African tree Pausinystalia johimbe. Yohimbine is the major active constituent of the bark, with the active ingredient being yohimbine hydrochloride. It is a supplement known for its ability to treat erectile dysfunction and help with weight loss.

Yohimbine is a drug used in veterinary medicine to reverse the effects of xylazine in dogs and deer. It is used as a research reagent. In the US it is prescribed, but now rarely, for erectile dysfunction in men.

Subjective effects

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

• • Stimulation
  • Appetite suppression
  • Dizziness
  • Headaches
  • Increased blood pressure
  • Decreased blood pressure
  • Increased heart rate
  • Increased perspiration
  • Stamina enhancement
  • Vasoconstriction
  • Pain relief

Cognitive effects

• • Anxiety suppression
  • Analysis enhancement
  • Anxiety
  • Increased libido
  • Irritability
  • Memory enhancement
  • Motivation enhancement
  • Thought acceleration
  • Wakefulness
  • Cognitive dysphoria

Experience reports

There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:

• Erowid Experience Vaults: Yohimbine

Toxicity and harm potential

Dangerous interactions

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

See also

• Responsible use
• Stimulants
• MAOI

External links

• Yohimbine (Wikipedia)
• Yohimbine (TiHKAL / Isomer Design)