Salvinorin B methoxymethyl ether

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Summary sheet: Salvinorin B methoxymethyl ether

Salvinorin B methoxymethyl ether
Chemical Nomenclature
Substitutive name	Salvinorin B
Systematic name	methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-(methoxymethoxy)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
Class Membership
Psychoactive class	Hallucinogen
Chemical class	Salvinorin
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Smoked Dosage Threshold 100 µg Light ?"?" is not a number. - ?"?" is not a number. µg Common ?"?" is not a number. - ?"?" is not a number. µg Strong 275 - 425 µg Heavy ?"?" is not a number.+ mg Duration Total 3 - 3 hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Interactions

Salvinorin B methoxymethyl ether (2-O-methoxymethylsalvinorin B, or 2-MMSB) is a semi-synthetic analogue of the natural product Salvinorin A which is used in scientific research. It has a longer duration of action of around 2–3 hours, compared to less than 30 minutes for salvinorin A, and has increased affinity and potency at the κ-opioid receptor. Like the related compound herkinorin, salvinorin B methoxymethyl ether is made from salvinorin B, which is most conveniently made from salvinorin A by deacetylation, as while both salvinorin A and salvinorin B are found in the plant Salvia divinorum, salvinorin A is present in larger quantities.

Salvinorin B methoxymethyl ether has a Ki of 0.60 nM at the κ opioid receptor, and is around five times more potent than salvinorin A in animal studies, although it is still only half as potent as its stronger homolog salvinorin B ethoxymethyl ether.

Experience reports

There are currently 0 experience reports describing the effects of this substance in our experience index. You can also submit your own experience report using the same link.

Additional experience reports can be found here:

• Erowid Experience Vaults: Salvinorin B Ethoxymethyl Ether Reports

See also

• Responsible use
• Salvinorin A
• Dissociatives
• Psychoactive substance index

External links

• Salvinorin B methoxymethyl ether (Wikipedia)
• Salvinorin B methoxymethyl ether (Erowid Vault)
• Salvinorin B methoxymethyl ether (Isomer Design)

References

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