This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Talk:ΒOH-2C-B
From PsychonautWiki Archive
Revision as of 13:24, 17 February 2024 by >Mydriasis(Added some info on dosage and duration.)
βOH-2C-B is perhaps three times less potent than 2C-B by weight, with normal recreational dosages reportedly ranging between 20-60mg. a It is thought to have a similarly steep dose-response curve to 2C-B. Theduration of action fo βOH-2C-B appears to be between 12-15 hours, with some users experience effects lasting well beyond the 16-hour mark.
βOH-2C-B is relatively uncommon and has little to no history of human usage prior to 2020 when it began to appear and be distributed by online vendors as a research chemical.
Very little data exists about the pharmacological properties, metabolism, and toxicity of βOH-2C-B. As a result, users are advised to approach this novel and poorly understood hallucinogenic substance with the proper amount of precaution and harm reduction practices if choosing to use it.
Experience reports of βOH-2C-B began to appear on the internet circa 2020, following its appearance online by gray-market research chemical vendors.
βOH-2C-B is considered a relatively obscure substance, even among research chemicals. An analysis of the Google search history between 2004-2024 shows that βOH-2C-B was inconsistently searched for during this time (about 32 times less often than 2C-B).[1]
Chemistry
βOH-2C-B, or beta-hydroxy 2C-B, is a substituted phenethylamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. βOH-2C-B contains the structure of 2C-B substituted with a hydroxy group at the beta carbon of the structure (R1). βOH-2C-B contains methoxy functional groups CH3O- attached to carbons R2 and R5 as well as a bromine atom attached to carbon R4 of the phenyl ring. βOH-2C-B belongs to the 2C family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring.[2]
βOH-2C-B likely acts as a 5-HT2Apartial agonist. The psychedelic effects are believed to come from its efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
The toxicity and long-term health effects of recreational βOH-2C-B use do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because βOH-2C-B is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried βOH-2C-B suggests that there are no negative health effects attributed to simply trying the substance by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.
Some users have reported headaches and migraines towards the end of their βOH-2C-B experience, which may indicate a potential toxicity.
As with psychedelics in general, βOH-2C-B is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.
Tolerance to the effects of βOH-2C-B are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). βOH-2C-B presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of βOH-2C-B, all psychedelics will have a reduced effect.
As such, it may contain incomplete or wrong information. You can help by expanding it.
Germany: βOH-2C-B is controlled under the NpSG (New Psychoactive Substances Act) as of November 26, 2016.[3][4] Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized.[5]
Netherlands: βOH-2C-B is a 2-phenethylamine ring-substituted derivative and thus falls under the 2024 analogue update to the Dutch Opium Act.
United Kingdom: It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.[6]
