Ephenidine

Ephenidine
Chemical Nomenclature
Common names	DMT, Dimethyltryptamine, Dmitri
Substitutive name	N,N-Dimethyltryptamine
Systematic name	2-(1H-Indol-3-yl)-N,N-dimethylethanamine
Class Membership
Psychoactive class	Psychedelic
Chemical class	Tryptamine
Routes of Administration
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Interactions
Stimulants
Depressants

Chemistry

This chemistry section is incomplete. You can help by adding to it.

Pharmacology

Main article: NMDA receptor antagonist

Diphenidine acts as an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. NMDA receptor antagonists close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually the famous “hole”.

Toxicity and harm potential

Lethal dosage

The toxicity and long term health effects of recreational ephenidine use does not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because ephenidine is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried ephenidine within the psychonaut community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

Tolerance and addiction potential

There is a very strong tolerance build up with ephenidine which results in the need to consume increasingly large doses in order to achieve the same level of effects. This should reset to baseline after 1 - 2 weeks. There may well be some addictive potential but this is still unknown.

Legal issues

Ephenidine is currently a legal grey area drug worldwide and is freely available through the use of online research chemical vendors. However, this does not guarantee anyone to be immune from legal prosecution should they be found in possession of this substance as the legality is likely to vary from country to country.

See also

• Dissociative
• Diphenidine
• Methoxphenidine
• Methoxetamine