Fentanyl/Summary

This substance is extraordinarily potent (i.e. active in the microgram range). For this reason, it should be handled with extreme care and never be eyeballed. Fentanyl can also be fatal when combined with depressants such as opiates, benzodiazepines, barbiturates, gabapentinoids, thienodiazepines or other GABAergic substances. It is strongly encouraged to wear gloves while handling, use volumetric dosing combined with a milligram scale, and to not consume either moderate or heavy dosages of other depressants in combination with this drug.

Main article: Fentanyl

Psychoactive class: Opioids

Chemical class: Substituted piperidines, Anilidopiperidine

Sublingual

• Thresh				Common				Heavy
  5	-	10	-	25	-	50	-	75	μg
  		Light				Strong

• • Total: 1 - 4 hours
  • Onset: 15 - 30 minutes

Insufflated

• Thresh				Common				Heavy
  5	-	10	-	25	-	50	-	75	μg
  		Light				Strong

• • Total: 1 - 4 hours
  • Onset: 15 - 30 minutes

Transdermal

• Thresh				Common				Heavy
  5	-	12	-	25	-	50	-	100	μg
  		Light				Strong

• • Total: 48 - 72 hours
  • Onset: 2 - 4 hours

Harm potential

• • Extremely addictive with a high potential for abuse
  • Potentially fatal at heavy dosages, unintentionally transporting the substance from the skin by touching the mouth, nose or eyes is dangerous

Tolerance

• • Full tolerance is reached develops with prolonged and repeated use
  • Decreases to half after 3 - 7 days
  • Returns to baseline after 1 - 2 weeks

Physical effects

• • Appetite suppression
  • Cough suppression
  • Pain relief
  • Respiratory depression
  • Sedation
• • Constipation
  • Decreased blood pressure
  • Difficulty urinating
  • Increased perspiration
  • Itchiness
  • Respiratory depression

Visual effects

Cognitive effects

• • Cognitive euphoria
  • Compulsive redosing
• • Anxiety suppression

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index