
Motor control loss
Motor control loss can be defined as a suppression of the process by which humans and other animals organize and execute their physical actions. Fundamentally, it is the integration of sensory information (both about the world and the current state of the body) to determine the appropriate set of muscle forces and joint activations to generate some desired movement or action. This process requires cooperative interaction between the central nervous system and the musculoskeletal system, and is thus the result of a combination of information processing, coordination, mechanics, physics, and cognition. Successful motor control is crucial to interacting with the world; it not only determines action capabilities, but regulates balance and stability as well.
In terms of hallucinogenic drugs, although in certain contexts these substances can actually enhance motor control through the component known as increased bodily control, it's worth noting that more often than not they simply decrease it.
The experience of motor control loss ranges between subtle and all-encompassing in its effects as at lower levels it simply results in a general sense of difficulty when performing physical tasks involving dexterity, walking, and balance. At higher levels, however, this component moves beyond subtle in its effects and becomes capable of completely disabling one's ability to use any level of fine or gross motor control. This results in catatonic states and the inability to perform any task beyond lying or sitting down regardless of the person's current cognitive capabilities.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 1,4-Butanediol
- 2-Fluorodeschloroketamine
- 2M2B
- 3-MeO-PCE
- 3-MeO-PCMo
- 4-MeO-PCP
- 5-MeO-DMT
- 5F-AKB48
- 5F-PB-22
- AB-FUBINACA
- APICA
- Alcohol
- Alprazolam
- Ayahuasca
- Baclofen
- Barbiturates
- Benzodiazepines
- Benzydamine
- Bromazepam
- Bufotenin
- Cannabis
- Carisoprodol
- Clonazepam
- Clonazolam
- DPT
- Datura
- Deschloroketamine
- Dextromethorphan
- DiPT
- Diazepam
- Diclazepam
- Diphenhydramine
- Diphenidine
- EPT
- Ephenidine
- Eszopiclone
- Etizolam
- Experience:3-MeO-PCP, LSD, Clonazolam, and Amphetamine - Excessive Amounts and Excessive Confusion
- F-Phenibut
- Flualprazolam
- Flubromazepam
- Flubromazolam
- Flunitrazepam
- Flunitrazolam
- GBL
- GHB
- Gabapentin
- HXE
- JWH-018
- JWH-073
Experience reports
Anecdotal reports which describe this effect within our experience index include:
- Experience: 1.5g Psilocybe Cubensis - Analysis of body and mind
- Experience: 105mg Ephenidine - An Intense Emotional Experience
- Experience: 550mg DPH - My First Time on DPH
- Experience: 80mg EPT - Slight improvement
- Experience:1000 Morning Glory seeds - Rediscovering the Self
- Experience:2 tabs DOB - My DOB Nightmare
- Experience:20mg Etizolam - Smoking Etizolam
- Experience:225mg Pregabalin +Cannabis -Bliss and Serenity; a hedonistic evening
- Experience:250mg MDA / 250mg MDMA - unnecessarily large dosage
- Experience:260 mg Ketamine (insufflated) - Lost in Paisley
- Experience:2g Syrian rue + 1g Mimosa Hostilis - These voices are the building blocks of consciousness
- Experience:2mg Etizolam & N2O - "Hippy Crack" Indeed
- Experience:3 bowls of cannabis indica - I wrote down unintelligible gibberish
- Experience:3-MEO-PCMo (420mg) - Trip Report
- Experience:3-MeO-PCP, LSD, Clonazolam, and Amphetamine - Excessive Amounts and Excessive Confusion
- Experience:300µg ETH-LAD - Turned Inside Out
- Experience:3g Syrian Rue + 5g Acacia Confusa - Life Changing Madness
- Experience:3mg Etizolam - A Comedown Drug
- Experience:400mg DXM + 300mg DPH – Bacterial friends
- Experience:50mg - Diphenidine ride
- Experience:50mg - How's the short-term memory?
- Experience:700mg - Joining the 700 club
- Experience:750mg - Experiencing Void; Dissociation Of Reality And Self
- Experience:800-900mg Ephenidine + unknown quantity flubroalzolam - Multiday Insanity
- Experience:Alprazolam (24 mg) - Into the Void
- Experience:BK-2C-B - Various experiences
- Experience:Ephenidine:185mg - A Weird and Rewarding Trip
- Experience:LSA (20 HWBR seeds) – A pleasant adventure with a harsh body load
- Experience:LSD (150µg) + Cannabis - 150µg lsd and a shitload of weed
- Experience:Nitrous oxide (approx. 50 puffs) - ~50 puffs nitrous oxide
- Experience:Nutmeg (8 teaspoons) - My Mom Introduces Me To Genesis and Other Things
- Experience:Unknown Dose DOC (Insufflated) - Overdosing and Terifying Ego Death
- Experience:~150mg MDA(oral) - a case of mistaken identity